An assay measuring the expression of lacZ shows the tissue where the gene is expressed.
| Anatomy |
Images |
Zygosity |
Mutant Expr |
| Bone |
Section images
|
heterozygote |
100% (1 of 1)
|
| Esophagus |
Section images
|
heterozygote |
100% (2 of 2)
|
| Heart |
Section images
|
heterozygote |
50% (1 of 2)
|
| Lung |
Section images
|
heterozygote |
100% (2 of 2)
|
| Pituitary gland |
Section images
|
heterozygote |
50% (1 of 2)
|
| Stomach |
Section images
|
heterozygote |
100% (2 of 2)
|
| Trachea |
Section images
|
heterozygote |
100% (2 of 2)
|
| Vascular system |
Section images
|
heterozygote |
100% (2 of 2)
|
| Adrenal gland |
N/A
|
heterozygote |
0.0% (0 of 2)
|
| Aorta |
N/A
|
heterozygote |
0.0% (0 of 2)
|
| Brain |
N/A
|
heterozygote |
50% (1 of 2)
|
| Brainstem |
N/A
|
heterozygote |
0.0% (0 of 2)
|
| Cartilage tissue |
N/A
|
heterozygote |
0.0% (0 of 2)
|
| Cerebellum |
N/A
|
heterozygote |
0.0% (0 of 2)
|
| Cerebral cortex |
N/A
|
heterozygote |
0.0% (0 of 2)
|
| Eye |
N/A
|
heterozygote |
0.0% (0 of 2)
|
| Hippocampus |
N/A
|
heterozygote |
0.0% (0 of 2)
|
| Hypothalamus |
N/A
|
heterozygote |
0.0% (0 of 2)
|
| Kidney |
N/A
|
heterozygote |
100% (2 of 2)
|
| Large intestine |
N/A
|
heterozygote |
100% (2 of 2)
|
| Liver |
N/A
|
heterozygote |
0.0% (0 of 2)
|
| Lower urinary tract |
N/A
|
heterozygote |
0.0% (0 of 2)
|
| Lymph node |
N/A
|
heterozygote |
0.0% (0 of 2)
|
| Mammary gland |
N/A
|
heterozygote |
0.0% (0 of 2)
|
| Olfactory lobe |
N/A
|
heterozygote |
0.0% (0 of 2)
|
| Ovary |
N/A
|
heterozygote |
50% (1 of 2)
|
| Oviduct |
N/A
|
heterozygote |
50% (1 of 2)
|
| Pancreas |
N/A
|
heterozygote |
0.0% (0 of 2)
|
| Peripheral nervous system |
N/A
|
heterozygote |
0.0% (0 of 2)
|
| Peyer's patch |
N/A
|
heterozygote |
0.0% (0 of 2)
|
| Prostate gland |
N/A
|
heterozygote |
50% (1 of 2)
|
| Skeletal muscle |
N/A
|
heterozygote |
0.0% (0 of 2)
|
| Skin |
N/A
|
heterozygote |
50% (1 of 2)
|
| Small intestine |
N/A
|
heterozygote |
100% (2 of 2)
|
| Spinal cord |
N/A
|
heterozygote |
0.0% (0 of 2)
|
| Spleen |
N/A
|
heterozygote |
0.0% (0 of 2)
|
| Striatum |
N/A
|
heterozygote |
0.0% (0 of 2)
|
| Testis |
N/A
|
heterozygote |
0.0% (0 of 2)
|
| Thymus |
N/A
|
heterozygote |
0.0% (0 of 2)
|
| Thyroid gland |
N/A
|
heterozygote |
50% (1 of 2)
|
| Tongue |
N/A
|
heterozygote |
100% (1 of 1)
|
| Uterus |
N/A
|
heterozygote |
50% (1 of 2)
|
| White adipose tissue |
N/A
|
heterozygote |
0.0% (0 of 2)
|
An assay measuring the expression of lacZ shows the tissue where the gene is expressed.
| Anatomy |
Images |
Zygosity |
Mutant Expr |
| Axial skeleton |
N/A
|
homozygote |
0.0% (0 of 1)
|
| Brain |
N/A
|
homozygote |
0.0% (0 of 1)
|
| Central nervous system ganglion |
N/A
|
homozygote |
100% (1 of 1)
|
| Ear |
N/A
|
homozygote |
0.0% (0 of 1)
|
| Embryo |
N/A
|
homozygote |
100% (1 of 1)
|
| Eye |
N/A
|
homozygote |
100% (1 of 1)
|
| Footplate |
N/A
|
homozygote |
100% (1 of 1)
|
| Forebrain |
N/A
|
homozygote |
0.0% (0 of 1)
|
| Forelimb |
N/A
|
homozygote |
100% (1 of 1)
|
| Gut |
N/A
|
homozygote |
100% (1 of 1)
|
| Handplate |
N/A
|
homozygote |
0.0% (0 of 1)
|
| Head |
N/A
|
homozygote |
0.0% (0 of 1)
|
| Heart |
N/A
|
homozygote |
0.0% (0 of 1)
|
| Hindbrain |
N/A
|
homozygote |
0.0% (0 of 1)
|
| Hindlimb |
N/A
|
homozygote |
100% (1 of 1)
|
| Liver |
N/A
|
homozygote |
100% (1 of 1)
|
| Lung |
N/A
|
homozygote |
0.0% (0 of 1)
|
| Mandibular process |
N/A
|
homozygote |
0.0% (0 of 1)
|
| Maxillary process |
N/A
|
homozygote |
0.0% (0 of 1)
|
| Midbrain |
N/A
|
homozygote |
0.0% (0 of 1)
|
| Nose |
N/A
|
homozygote |
100% (1 of 1)
|
| Oral cavity |
N/A
|
homozygote |
0.0% (0 of 1)
|
| Skeleton |
N/A
|
homozygote |
0.0% (0 of 1)
|
| Skin |
N/A
|
homozygote |
0.0% (0 of 1)
|
| Spinal cord |
N/A
|
homozygote |
0.0% (0 of 1)
|
| Tail somite |
N/A
|
homozygote |
100% (1 of 1)
|
| Tail |
N/A
|
homozygote |
0.0% (0 of 1)
|
| Trachea |
N/A
|
homozygote |
100% (1 of 1)
|
| Urinary system |
N/A
|
homozygote |
100% (1 of 1)
|
Background staining occurs in wild type mice and embryos at an incidental rate.
| Anatomy |
Background staining in controls (WT) |
| adrenal gland |
0.67% (4 of 598)
|
| aorta |
0.17% (1 of 598)
|
| bone |
0.0%
|
| brain |
0.84% (5 of 598)
|
| brainstem |
0.33% (2 of 598)
|
| cartilage tissue |
0.17% (1 of 598)
|
| cerebellum |
0.5% (3 of 598)
|
| cerebral cortex |
0.33% (2 of 598)
|
| esophagus |
1.66% (7 of 422)
|
| eye |
0.0%
|
| heart |
0.33% (2 of 598)
|
| hippocampus |
0.5% (3 of 598)
|
| hypothalamus |
0.33% (2 of 598)
|
| kidney |
4.52% (27 of 598)
|
| large intestine |
5.35% (32 of 598)
|
| liver |
0.0%
|
| lower urinary tract |
0.17% (1 of 598)
|
| lung |
0.33% (2 of 598)
|
| lymph node |
0.17% (1 of 598)
|
| mammary gland |
0.0%
|
| olfactory lobe |
0.33% (2 of 598)
|
| ovary |
0.17% (1 of 598)
|
| oviduct |
0.0%
|
| pancreas |
0.84% (5 of 598)
|
| peripheral nervous system |
0.33% (2 of 598)
|
| peyers patch |
0.0%
|
| pituitary gland |
0.17% (1 of 598)
|
| prostate gland |
2.17% (13 of 598)
|
| skeletal muscle |
0.0%
|
| skin |
0.17% (1 of 598)
|
| small intestine |
5.35% (32 of 598)
|
| spinal cord |
0.5% (3 of 598)
|
| spleen |
0.5% (3 of 598)
|
| stomach |
3.68% (22 of 598)
|
| striatum |
0.5% (3 of 598)
|
| testis |
1% (6 of 598)
|
| thymus |
0.17% (1 of 598)
|
| thyroid gland |
3.01% (18 of 598)
|
| tongue |
3.57% (5 of 140)
|
| trachea |
0.5% (3 of 598)
|
| uterus |
0.33% (2 of 598)
|
| vascular system |
0.0%
|
| white adipose tissue |
0.0%
|
Background staining occurs in wild type mice and embryos at an incidental rate.
Background staining occurs in wild type embryos at a measurable rate.
| Anatomy |
Background staining in controls(WT) |
| axial skeleton |
1.56% (1 of 64)
|
| brain |
1.17% (6 of 511)
|
| central nervous system ganglion |
1.37% (1 of 73)
|
| ear |
0.2% (1 of 511)
|
| embryo |
0.39% (2 of 512)
|
| eye |
0.2% (1 of 511)
|
| footplate |
0.2% (1 of 511)
|
| forebrain |
0.2% (1 of 511)
|
| forelimb |
0.2% (1 of 511)
|
| gut |
1.69% (1 of 59)
|
| handplate |
0.2% (1 of 511)
|
| head |
0.98% (5 of 511)
|
| heart |
0.2% (1 of 511)
|
| hindbrain |
1.17% (6 of 511)
|
| hindlimb |
0.2% (1 of 511)
|
| liver |
0.2% (1 of 506)
|
| lung |
0.2% (1 of 506)
|
| mandibular process |
0.2% (1 of 511)
|
| maxillary process |
0.2% (1 of 511)
|
| midbrain |
0.2% (1 of 511)
|
| nose |
1.28% (1 of 78)
|
| oral cavity |
0.2% (1 of 506)
|
| skeleton |
1.28% (1 of 78)
|
| skin |
0.2% (1 of 511)
|
| spinal cord |
1.39% (1 of 72)
|
| tail |
0.2% (1 of 511)
|
| tail somite group |
0.2% (1 of 511)
|
| trachea |
1.69% (1 of 59)
|
| urinary system |
1.69% (1 of 59)
|
