Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data preweaning lethality, complete penetrance Lef1 homozygote not_considered Early adult Viability Primary Screen Homozygous animals viability UC Davis IMPC 0.0 //beta.mousephenotype.org/data/charts?accession=MGI:96770&allele_accession_id=MGI:5708280&zygosity=homozygote¶meter_stable_id=IMPC_VIA_067_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_067_001&phenotyping_center=UC Davis preweaning lethality, complete penetrance Lef1 homozygote male Early adult Viability Primary Screen Homozygous males viability UC Davis IMPC 0.0 //beta.mousephenotype.org/data/charts?accession=MGI:96770&allele_accession_id=MGI:5708280&zygosity=homozygote¶meter_stable_id=IMPC_VIA_063_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_063_001&phenotyping_center=UC Davis abnormal craniofacial morphology Lef1 homozygote female E15.5 Gross Morphology Embryo E14.5-E15.5 Craniofacial morphology TCP IMPC 0.0 //beta.mousephenotype.org/data/charts?accession=MGI:96770&allele_accession_id=MGI:5708280&zygosity=homozygote¶meter_stable_id=IMPC_GEO_063_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_GEO_003¶meter_stable_id=IMPC_GEO_063_001&phenotyping_center=TCP abnormal craniofacial morphology Lef1 homozygote male E15.5 Gross Morphology Embryo E14.5-E15.5 Craniofacial morphology TCP IMPC 0.0 //beta.mousephenotype.org/data/charts?accession=MGI:96770&allele_accession_id=MGI:5708280&zygosity=homozygote¶meter_stable_id=IMPC_GEO_063_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_GEO_003¶meter_stable_id=IMPC_GEO_063_001&phenotyping_center=TCP abnormal heart morphology Lef1 heterozygote female Early adult Gross Pathology and Tissue Collection Heart UC Davis IMPC 0.0 //beta.mousephenotype.org/data/grosspath/MGI:96770/IMPC_PAT_006_002 preweaning lethality, complete penetrance Lef1 homozygote female Early adult Viability Primary Screen Homozygous females viability UC Davis IMPC 0.0 //beta.mousephenotype.org/data/charts?accession=MGI:96770&allele_accession_id=MGI:5708280&zygosity=homozygote¶meter_stable_id=IMPC_VIA_064_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_064_001&phenotyping_center=UC Davis abnormal craniofacial morphology Lef1 homozygote male E15.5 Gross Morphology Embryo E14.5-E15.5 Craniofacial morphology TCP IMPC 0.0 //beta.mousephenotype.org/data/charts?accession=MGI:96770&allele_accession_id=MGI:5708280&zygosity=homozygote¶meter_stable_id=IMPC_GEO_063_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_GEO_003¶meter_stable_id=IMPC_GEO_063_001&phenotyping_center=TCP enlarged heart Lef1 heterozygote female Early adult Gross Pathology and Tissue Collection Heart UC Davis IMPC 0.0 //beta.mousephenotype.org/data/grosspath/MGI:96770/IMPC_PAT_006_002 abnormal craniofacial morphology Lef1 homozygote female E15.5 Gross Morphology Embryo E14.5-E15.5 Craniofacial morphology TCP IMPC 0.0 //beta.mousephenotype.org/data/charts?accession=MGI:96770&allele_accession_id=MGI:5708280&zygosity=homozygote¶meter_stable_id=IMPC_GEO_063_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_GEO_003¶meter_stable_id=IMPC_GEO_063_001&phenotyping_center=TCP decreased prepulse inhibition Lef1 heterozygote not_considered Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI2 UC Davis IMPC 2.43E-6 //beta.mousephenotype.org/data/charts?accession=MGI:96770&allele_accession_id=MGI:5708280&zygosity=heterozygote¶meter_stable_id=IMPC_ACS_034_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_034_001&phenotyping_center=UC Davis decreased prepulse inhibition Lef1 heterozygote not_considered Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI3 UC Davis IMPC 5.06E-5 //beta.mousephenotype.org/data/charts?accession=MGI:96770&allele_accession_id=MGI:5708280&zygosity=heterozygote¶meter_stable_id=IMPC_ACS_035_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_035_001&phenotyping_center=UC Davis increased monocyte cell number Lef1 heterozygote male Early adult Hematology Monocyte differential count UC Davis IMPC 5.7E-5 //beta.mousephenotype.org/data/charts?accession=MGI:96770&allele_accession_id=MGI:5708280&zygosity=heterozygote¶meter_stable_id=IMPC_HEM_033_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_HEM_002¶meter_stable_id=IMPC_HEM_033_001&phenotyping_center=UC Davis