Significant MP calls for MARC Strains (IMPC_001)  

 

Total number of results: 1318

Gene / Allele Procedure Parameter Zygosity Sex Phenotype P-value Graph
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Thymus homozygote Male small thymus 0.0
Fbxo15
Fbxo15em1(IMPC)Marc
Gross Pathology and Tissue Collection Spleen homozygote Female enlarged spleen 0.0
Jade1
Jade1tm1b(KOMP)Wtsi
Fertility of Homozygous Knock-out Mice Gross Findings Male homozygote Male male infertility 0.0
Kdm1a
Kdm1atm1(NCOM)Mfgc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Emc7
Emc7tm1b(KOMP)Mbp
Viability Primary Screen Viability Outcome homozygote preweaning lethality, incomplete penetrance 0.0
Lhcgr
Lhcgrtm1(KOMP)Vlcg
Gross Pathology and Tissue Collection Stomach homozygote Male small stomach 0.0
Usp15
Usp15em1(IMPC)Marc
Fertility of Homozygous Knock-out Mice Gross Findings Female homozygote Female female infertility 0.0
Ctu2
Ctu2tm1(KOMP)Wtsi
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Hnrnpm
Hnrnpmem1(IMPC)Marc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Lung homozygote Female small lung 0.0
Snx25
Snx25tm1b(KOMP)Wtsi
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Dagla
Daglatm1a(EUCOMM)Wtsi
Gross Pathology and Tissue Collection Brain homozygote Male decreased brain size 0.0
Lhcgr
Lhcgrtm1(KOMP)Vlcg
Gross Pathology and Tissue Collection Heart homozygote Male small heart 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Stomach homozygote Male small stomach 0.0
Kdm1a
Kdm1atm1(NCOM)Mfgc
Gross Pathology and Tissue Collection Liver heterozygote Female small liver 0.0
Kmt2a
Kmt2aem1(IMPC)Marc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Kdm1a
Kdm1atm1(NCOM)Mfgc
Gross Pathology and Tissue Collection Spleen heterozygote Female small spleen 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Spleen homozygote Female small spleen 0.0
Dusp7
Dusp7tm1(KOMP)Wtsi
Fertility of Homozygous Knock-out Mice Gross Findings Female homozygote Female female infertility 0.0
Ccdc124
Ccdc124tm1b(KOMP)Wtsi
Gross Pathology and Tissue Collection Lung homozygote Male small lung 0.0
Fbxw8
Fbxw8tm1b(EUCOMM)Hmgu
Viability Primary Screen Viability Outcome homozygote preweaning lethality, incomplete penetrance 0.0
Kmt2c
Kmt2cem2(IMPC)Marc
Gross Pathology and Tissue Collection Spleen heterozygote Female enlarged spleen 0.0
Kdm1a
Kdm1atm1(NCOM)Mfgc
Gross Pathology and Tissue Collection Kidney heterozygote Female small kidney 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Thymus homozygote Male small thymus 0.0
Bnip1
Bnip1tm2b(KOMP)Wtsi
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Ccdc124
Ccdc124tm1b(KOMP)Wtsi
Gross Pathology and Tissue Collection Liver homozygote Male small liver 0.0
Kdm1a
Kdm1atm1(NCOM)Mfgc
Gross Pathology and Tissue Collection Heart heterozygote Female small heart 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Liver homozygote Female small liver 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Heart homozygote Male small heart 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Stomach homozygote Female small stomach 0.0
Fbxo43
Fbxo43em1(IMPC)Marc
Fertility of Homozygous Knock-out Mice Gross Findings Female homozygote Female female infertility 0.0
Kdm1a
Kdm1atm1(NCOM)Mfgc
Gross Pathology and Tissue Collection Lung heterozygote Female small lung 0.0
Usp32
Usp32em1(IMPC)Mhzh
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Dagla
Daglatm1a(EUCOMM)Wtsi
Gross Pathology and Tissue Collection Stomach homozygote Male small stomach 0.0
Ccdc124
Ccdc124tm1b(KOMP)Wtsi
Gross Pathology and Tissue Collection Lung homozygote Female small lung 0.0
Tsg101
Tsg101tm1b(EUCOMM)Hmgu
Gross Pathology and Tissue Collection Kidney heterozygote Female abnormal kidney morphology 0.0
Ccdc124
Ccdc124tm1b(KOMP)Wtsi
Gross Pathology and Tissue Collection Heart homozygote Male small heart 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Brain homozygote Female decreased brain size 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Thymus homozygote Female small thymus 0.0
Fbxo22
Fbxo22tm1b(EUCOMM)Wtsi
Fertility of Homozygous Knock-out Mice Gross Findings Female homozygote Female female infertility 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Spleen homozygote Male small spleen 0.0
Kmt2c
Kmt2cem2(IMPC)Marc
Gross Pathology and Tissue Collection Spleen heterozygote Female enlarged spleen 0.0
Psmd14
Psmd14tm1b(NCOM)Cmhd
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Dusp7
Dusp7tm1(KOMP)Wtsi
Fertility of Homozygous Knock-out Mice Gross Findings Male homozygote Male male infertility 0.0
Fbxl5
Fbxl5em1(IMPC)Marc
Gross Pathology and Tissue Collection Spleen heterozygote Female enlarged spleen 0.0
Dagla
Daglatm1a(EUCOMM)Wtsi
Gross Pathology and Tissue Collection Spleen homozygote Male small spleen 0.0
Ccdc124
Ccdc124tm1b(KOMP)Wtsi
Gross Pathology and Tissue Collection Brain homozygote Male decreased brain size 0.0
Ccdc124
Ccdc124tm1b(KOMP)Wtsi
Gross Pathology and Tissue Collection Lung homozygote Male small lung 0.0
Ccdc124
Ccdc124tm1b(KOMP)Wtsi
Gross Pathology and Tissue Collection Spleen homozygote Female small spleen 0.0
Cyp3a59
Cyp3a59em1(IMPC)Marc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Dagla
Daglatm1a(EUCOMM)Wtsi
Gross Pathology and Tissue Collection Liver homozygote Male small liver 0.0
Kdm1a
Kdm1atm1(NCOM)Mfgc
Gross Pathology and Tissue Collection Lung heterozygote Female small lung 0.0
Bend3
Bend3tm1b(KOMP)Mbp
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Lhcgr
Lhcgrtm1(KOMP)Vlcg
Gross Pathology and Tissue Collection Liver homozygote Male small liver 0.0
Ccdc124
Ccdc124tm1b(KOMP)Wtsi
Gross Pathology and Tissue Collection Brain homozygote Female decreased brain size 0.0
Ccdc124
Ccdc124tm1b(KOMP)Wtsi
Gross Pathology and Tissue Collection Lung homozygote Female small lung 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Thymus homozygote Female small thymus 0.0
Hnrnph1
Hnrnph1tm1b(KOMP)Wtsi
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Ccdc124
Ccdc124tm1b(KOMP)Wtsi
Gross Pathology and Tissue Collection Liver homozygote Female small liver 0.0
Carm1
Carm1tm1b(EUCOMM)Hmgu
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Ppp2r1b
Ppp2r1btm1b(EUCOMM)Wtsi
Fertility of Homozygous Knock-out Mice Gross Findings Male homozygote Male male infertility 0.0
Prpf31
Prpf31tm1a(EUCOMM)Wtsi
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Liver homozygote Female small liver 0.0
Fbxl5
Fbxl5em1(IMPC)Marc
Gross Pathology and Tissue Collection Spleen heterozygote Female enlarged spleen 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Fertility of Homozygous Knock-out Mice Gross Findings Male homozygote Male male infertility 0.0
Fbxo15
Fbxo15em1(IMPC)Marc
Gross Pathology and Tissue Collection Spleen homozygote Female enlarged spleen 0.0
Kdm1a
Kdm1atm1(NCOM)Mfgc
Gross Pathology and Tissue Collection Spleen heterozygote Female small spleen 0.0
Spata16
Spata16em1(IMPC)Marc
Fertility of Homozygous Knock-out Mice Gross Findings Male homozygote Male male infertility 0.0
Lhcgr
Lhcgrtm1(KOMP)Vlcg
Gross Pathology and Tissue Collection Thymus homozygote Male small thymus 0.0
Kdm1a
Kdm1atm1(NCOM)Mfgc
Gross Pathology and Tissue Collection Heart heterozygote Female small heart 0.0
Dagla
Daglatm1a(EUCOMM)Wtsi
Gross Pathology and Tissue Collection Brain homozygote Male decreased brain size 0.0
Dagla
Daglatm1a(EUCOMM)Wtsi
Gross Pathology and Tissue Collection Spleen homozygote Male small spleen 0.0
Bbof1
Bbof1em1(IMPC)Marc
Fertility of Homozygous Knock-out Mice Gross Findings Male homozygote Male male infertility 0.0
Dagla
Daglatm1a(EUCOMM)Wtsi
Gross Pathology and Tissue Collection Heart homozygote Male small heart 0.0
Lhcgr
Lhcgrtm1(KOMP)Vlcg
Gross Pathology and Tissue Collection Liver homozygote Male small liver 0.0
Lhcgr
Lhcgrtm1(KOMP)Vlcg
Gross Pathology and Tissue Collection Thymus homozygote Male small thymus 0.0
Bod1
Bod1tm1b(KOMP)Wtsi
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Dagla
Daglatm1a(EUCOMM)Wtsi
Gross Pathology and Tissue Collection Lung homozygote Male small lung 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Heart homozygote Female small heart 0.0
Emc4
Emc4tm1(KOMP)Wtsi
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Ash1l
Ash1ltm2b(EUCOMM)Hmgu
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Spleen homozygote Male small spleen 0.0
Lhcgr
Lhcgrtm1(KOMP)Vlcg
Gross Pathology and Tissue Collection Lung homozygote Male small lung 0.0
Kdm1a
Kdm1atm1(NCOM)Mfgc
Gross Pathology and Tissue Collection Kidney heterozygote Female small kidney 0.0
Mir143
Mir143tm1(mirKO)Wtsi
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Ppp1cb
Ppp1cbem2(IMPC)Marc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Lhcgr
Lhcgrtm1(KOMP)Vlcg
Gross Pathology and Tissue Collection Brain homozygote Male decreased brain size 0.0
Ufm1
Ufm1em1(IMPC)Marc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Lhcgr
Lhcgrtm1(KOMP)Vlcg
Gross Pathology and Tissue Collection Brain homozygote Male decreased brain size 0.0
Prmt6
Prmt6em1(IMPC)Marc
Fertility of Homozygous Knock-out Mice Gross Findings Male homozygote Male male infertility 0.0
Ppp2r2a
Ppp2r2atm1b(KOMP)Wtsi
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Mir320
Mir320tm1(mirKO)Wtsi
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Spata16
Spata16em1(IMPC)Marc
Fertility of Homozygous Knock-out Mice Gross Findings Female homozygote Female female infertility 0.0
Mir429
Mir429tm1(mirKO)Wtsi
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Skp2
Skp2em2(IMPC)Marc
Fertility of Homozygous Knock-out Mice Gross Findings Female homozygote Female female infertility 0.0
Trim37
Trim37em1(IMPC)Marc
Fertility of Homozygous Knock-out Mice Gross Findings Male homozygote Male male infertility 0.0
Ccdc124
Ccdc124tm1b(KOMP)Wtsi
Gross Pathology and Tissue Collection Heart homozygote Female small heart 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Spleen homozygote Female small spleen 0.0
Erich2
Erich2em1(IMPC)Marc
Fertility of Homozygous Knock-out Mice Gross Findings Female homozygote Female female infertility 0.0
Usp10
Usp10tm1(NCOM)Mfgc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Liver homozygote Male small liver 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Lung homozygote Male small lung 0.0
Lhcgr
Lhcgrtm1(KOMP)Vlcg
Gross Pathology and Tissue Collection Spleen homozygote Male small spleen 0.0
Nxn
Nxntm1b(EUCOMM)Wtsi
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Bbof1
Bbof1em1(IMPC)Marc
Fertility of Homozygous Knock-out Mice Gross Findings Female homozygote Female female infertility 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Brain homozygote Male decreased brain size 0.0
Hoxc11
Hoxc11em1(IMPC)Marc
Fertility of Homozygous Knock-out Mice Gross Findings Male homozygote Male male infertility 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Brain homozygote Female decreased brain size 0.0
Lhcgr
Lhcgrtm1(KOMP)Vlcg
Gross Pathology and Tissue Collection Spleen homozygote Male small spleen 0.0
Ccdc124
Ccdc124tm1b(KOMP)Wtsi
Gross Pathology and Tissue Collection Brain homozygote Male decreased brain size 0.0
Dctd
Dctdem1(IMPC)Marc
Fertility of Homozygous Knock-out Mice Gross Findings Female homozygote Female female infertility 0.0
Mir141
Mir141tm1(mirKO)Wtsi
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Fbxo38
Fbxo38em2(IMPC)Marc
Gross Pathology and Tissue Collection Liver homozygote Female small liver 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Stomach homozygote Female small stomach 0.0
Dagla
Daglatm1a(EUCOMM)Wtsi
Gross Pathology and Tissue Collection Stomach homozygote Male small stomach 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Fertility of Homozygous Knock-out Mice Gross Findings Female homozygote Female female infertility 0.0
Tsg101
Tsg101tm1b(EUCOMM)Hmgu
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Fntb
Fntbtm1b(EUCOMM)Hmgu
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Bap1
Bap1em2(IMPC)Marc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Fbxo24
Fbxo24em2(IMPC)Marc
Fertility of Homozygous Knock-out Mice Gross Findings Male homozygote Male male infertility 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Lung homozygote Female small lung 0.0
Skp2
Skp2em2(IMPC)Marc
Fertility of Homozygous Knock-out Mice Gross Findings Male homozygote Male male infertility 0.0
Dagla
Daglatm1a(EUCOMM)Wtsi
Gross Pathology and Tissue Collection Thymus homozygote Male small thymus 0.0
Cyp3a41b
Cyp3a41btm1b(KOMP)Wtsi
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Stomach homozygote Male small stomach 0.0
Dagla
Daglatm1a(EUCOMM)Wtsi
Gross Pathology and Tissue Collection Thymus homozygote Male small thymus 0.0
Dagla
Daglatm1a(EUCOMM)Wtsi
Gross Pathology and Tissue Collection Heart homozygote Male small heart 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Lung homozygote Male small lung 0.0
Alg1
Alg1tm1b(KOMP)Wtsi
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Kmt2c
Kmt2cem2(IMPC)Marc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Usp50
Usp50tm1(KOMP)Vlcg
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Ccdc124
Ccdc124tm1b(KOMP)Wtsi
Gross Pathology and Tissue Collection Liver homozygote Male small liver 0.0
Kdm5a
Kdm5aem1(IMPC)Marc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Dagla
Daglatm1a(EUCOMM)Wtsi
Gross Pathology and Tissue Collection Lung homozygote Male small lung 0.0
Oxsm
Oxsmem2(IMPC)Marc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Ccdc124
Ccdc124tm1b(KOMP)Wtsi
Gross Pathology and Tissue Collection Brain homozygote Female decreased brain size 0.0
Trim37
Trim37em1(IMPC)Marc
Fertility of Homozygous Knock-out Mice Gross Findings Female homozygote Female female infertility 0.0
Dctd
Dctdem1(IMPC)Marc
Fertility of Homozygous Knock-out Mice Gross Findings Male homozygote Male male infertility 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Brain homozygote Male decreased brain size 0.0
Maob
Maobem1(IMPC)Marc
Fertility of Homozygous Knock-out Mice Gross Findings Male homozygote Male male infertility 0.0
Fbxo22
Fbxo22tm1b(EUCOMM)Wtsi
Fertility of Homozygous Knock-out Mice Gross Findings Male homozygote Male male infertility 0.0
Fbxo38
Fbxo38em2(IMPC)Marc
Fertility of Homozygous Knock-out Mice Gross Findings Male homozygote Male male infertility 0.0
Lhcgr
Lhcgrtm1(KOMP)Vlcg
Gross Pathology and Tissue Collection Lung homozygote Male small lung 0.0
Ccdc124
Ccdc124tm1b(KOMP)Wtsi
Gross Pathology and Tissue Collection Liver homozygote Female small liver 0.0
Fbxo38
Fbxo38em2(IMPC)Marc
Fertility of Homozygous Knock-out Mice Gross Findings Female homozygote Female female infertility 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Heart homozygote Male small heart 0.0
Uchl5
Uchl5tm1(NCOM)Mfgc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Lhcgr
Lhcgrtm1(KOMP)Vlcg
Gross Pathology and Tissue Collection Stomach homozygote Male small stomach 0.0
Ccdc124
Ccdc124tm1b(KOMP)Wtsi
Gross Pathology and Tissue Collection Heart homozygote Male small heart 0.0
Fbxo24
Fbxo24em2(IMPC)Marc
Fertility of Homozygous Knock-out Mice Gross Findings Female homozygote Female female infertility 0.0
Erich2
Erich2em1(IMPC)Marc
Fertility of Homozygous Knock-out Mice Gross Findings Male homozygote Male male infertility 0.0
Ezh1
Ezh1tm1b(EUCOMM)Wtsi
Fertility of Homozygous Knock-out Mice Gross Findings Male homozygote Male male infertility 0.0
Ccdc124
Ccdc124tm1b(KOMP)Wtsi
Gross Pathology and Tissue Collection Spleen homozygote Female small spleen 0.0
Ccdc124
Ccdc124tm1b(KOMP)Wtsi
Gross Pathology and Tissue Collection Spleen homozygote Male small spleen 0.0
Jade1
Jade1tm1b(KOMP)Wtsi
Fertility of Homozygous Knock-out Mice Gross Findings Female homozygote Female female infertility 0.0
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Fbxo43
Fbxo43em1(IMPC)Marc
Fertility of Homozygous Knock-out Mice Gross Findings Male homozygote Male male infertility 0.0
Ccdc124
Ccdc124tm1b(KOMP)Wtsi
Gross Pathology and Tissue Collection Heart homozygote Female small heart 0.0
Usp15
Usp15em1(IMPC)Marc
Fertility of Homozygous Knock-out Mice Gross Findings Male homozygote Male male infertility 0.0
Lhcgr
Lhcgrtm1(KOMP)Vlcg
Gross Pathology and Tissue Collection Heart homozygote Male small heart 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Heart homozygote Female small heart 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
Gross Pathology and Tissue Collection Liver homozygote Male small liver 0.0
Dagla
Daglatm1a(EUCOMM)Wtsi
Gross Pathology and Tissue Collection Liver homozygote Male small liver 0.0
Ccdc124
Ccdc124tm1b(KOMP)Wtsi
Gross Pathology and Tissue Collection Spleen homozygote Male small spleen 0.0
Aars2
Aars2tm1(KOMP)Wtsi
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Kdm1a
Kdm1atm1(NCOM)Mfgc
Gross Pathology and Tissue Collection Liver heterozygote Female small liver 0.0
Zswim1
Zswim1tm1b(KOMP)Mbp
Hematology Basophil cell count homozygote Female increased basophil cell number 0.0
Cdc42ep5
Cdc42ep5tm1(KOMP)Wtsi
Hematology Basophil differential count homozygote Female increased basophil cell number 0.0
Cdc42ep5
Cdc42ep5tm1(KOMP)Wtsi
Hematology Eosinophil differential count homozygote Female increased eosinophil cell number 0.0
Zswim1
Zswim1tm1b(KOMP)Mbp
Hematology Eosinophil cell count homozygote Female increased eosinophil cell number 0.0
Ces2e
Ces2eem1(IMPC)Marc
Hematology Basophil differential count homozygote Male increased basophil cell number 0.0
Hectd4
Hectd4em1(IMPC)Marc
Hematology Basophil differential count heterozygote Female increased basophil cell number 0.0
Fbxl19
Fbxl19tm1b(EUCOMM)Wtsi
Hematology Monocyte cell count heterozygote Male increased monocyte cell number 0.0
Ppp1r14a
Ppp1r14aem1(IMPC)Marc
Hematology Eosinophil differential count homozygote Male increased eosinophil cell number 0.0
Ppp1r14a
Ppp1r14aem1(IMPC)Marc
Hematology Basophil differential count homozygote Male increased basophil cell number 0.0
Erich2
Erich2em1(IMPC)Marc
Hematology Eosinophil differential count homozygote Male increased eosinophil cell number 0.0
Cdc42ep5
Cdc42ep5tm1(KOMP)Wtsi
Hematology Eosinophil cell count homozygote Female increased eosinophil cell number 0.0
Usp31
Usp31em1(IMPC)Marc
Hematology Basophil differential count homozygote Female increased basophil cell number 0.0
Ppp1r14a
Ppp1r14aem1(IMPC)Marc
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 0.0
Zswim1
Zswim1tm1b(KOMP)Mbp
Hematology Basophil differential count homozygote Female increased basophil cell number 0.0
Cdc42ep5
Cdc42ep5tm1(KOMP)Wtsi
Hematology Basophil cell count homozygote Female increased basophil cell number 0.0
Usp31
Usp31em1(IMPC)Marc
Hematology Eosinophil differential count homozygote Female increased eosinophil cell number 0.0
Zswim1
Zswim1tm1b(KOMP)Mbp
Hematology Eosinophil differential count homozygote Female increased eosinophil cell number 1.401298464324817E-45
Brix1
Brix1tm1b(KOMP)Mbp
Hematology Basophil differential count heterozygote Female increased basophil cell number 8.407790785948902E-45
Erich2
Erich2em1(IMPC)Marc
Hematology Basophil cell count homozygote Male increased basophil cell number 3.0828566215145976E-44
Usp31
Usp31em1(IMPC)Marc
Hematology Basophil cell count homozygote increased basophil cell number 8.547920632381384E-44
Usp31
Usp31em1(IMPC)Marc
Hematology Mean cell volume homozygote Female decreased mean corpuscular volume 2.328397528322116E-41
Usp31
Usp31em1(IMPC)Marc
Hematology Mean cell hemoglobin concentration homozygote Female increased mean corpuscular hemoglobin concentration 5.945008734898036E-41
Fbxo43
Fbxo43em1(IMPC)Marc
Hematology Eosinophil differential count homozygote Female increased eosinophil cell number 1.5390601163525898E-40
Usp36
Usp36tm1b(EUCOMM)Hmgu
Clinical Chemistry Glucose heterozygote Female increased circulating glucose level 1.6291495946240323E-40
Hectd1
Hectd1tm1b(EUCOMM)Hmgu
Hematology Basophil cell count heterozygote increased basophil cell number 3.2095199897049178E-40
Etaa1
Etaa1em1(IMPC)Marc
Hematology Basophil differential count homozygote Male increased basophil cell number 5.115005641493804E-40
Ces2e
Ces2eem1(IMPC)Marc
Hematology Basophil cell count homozygote Male increased basophil cell number 1.0782586707723277E-38
Fbxo43
Fbxo43em1(IMPC)Marc
Hematology Basophil differential count homozygote Female increased basophil cell number 1.4489222932841281E-38
Erich2
Erich2em1(IMPC)Marc
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 1.6694234730081133E-38
Ces2e
Ces2eem1(IMPC)Marc
Hematology Eosinophil differential count homozygote Male increased eosinophil cell number 1.705613138098461E-36
Brix1
Brix1tm1b(KOMP)Mbp
Hematology Basophil cell count heterozygote Female increased basophil cell number 2.9012707613135305E-36
Usp31
Usp31em1(IMPC)Marc
Hematology Eosinophil cell count homozygote Female increased eosinophil cell number 5.782725503204126E-36
Spata16
Spata16em1(IMPC)Marc
Hematology Eosinophil differential count homozygote Female increased eosinophil cell number 8.011550753549347E-36
Cyld
Cyldem2(IMPC)Marc
Hematology Basophil cell count homozygote Male increased basophil cell number 1.9573423045466693E-35
Ube2e1
Ube2e1em1(IMPC)Marc
Hematology Mean cell hemoglobin concentration homozygote Male decreased mean corpuscular hemoglobin concentration 4.879138980843084E-35
Ube2e1
Ube2e1em1(IMPC)Marc
Hematology Mean cell volume homozygote Male increased mean corpuscular volume 5.747235819206833E-35
Hectd1
Hectd1tm1b(EUCOMM)Hmgu
Hematology Basophil differential count heterozygote Male increased basophil cell number 1.2345666153709538E-34
Prdm2
Prdm2em1(IMPC)Marc
Hematology Mean cell hemoglobin concentration homozygote Male increased mean corpuscular hemoglobin concentration 1.3490991396100223E-34
Etaa1
Etaa1em1(IMPC)Marc
Hematology Basophil cell count homozygote Male increased basophil cell number 1.6784384250292344E-33
Ube2e1
Ube2e1em1(IMPC)Marc
Hematology Mean cell volume homozygote Female increased mean corpuscular volume 5.849843596105283E-33
Prdm2
Prdm2em1(IMPC)Marc
Hematology Mean cell hemoglobin concentration homozygote Female increased mean corpuscular hemoglobin concentration 9.318212779261384E-33
Hnrnpr
Hnrnprem1(IMPC)Marc
Hematology Mean cell hemoglobin concentration homozygote Female decreased mean corpuscular hemoglobin concentration 7.78707819619598E-32
Suv39h2
Suv39h2em1(IMPC)Marc
Hematology Basophil cell count homozygote Male increased basophil cell number 9.90249371570554E-32
Spata16
Spata16em1(IMPC)Marc
Hematology Eosinophil differential count homozygote Male increased eosinophil cell number 9.925705027156877E-32
Itprid1
Itprid1em1(IMPC)Marc
Hematology Eosinophil differential count homozygote Male increased eosinophil cell number 8.896615206345323E-31
Hnrnpr
Hnrnprem1(IMPC)Marc
Hematology Mean cell hemoglobin concentration homozygote Male decreased mean corpuscular hemoglobin concentration 1.3097382507144425E-30
Spata16
Spata16em1(IMPC)Marc
Hematology Basophil differential count homozygote Female increased basophil cell number 1.5142269658648434E-30
Ube2e1
Ube2e1em1(IMPC)Marc
Hematology Mean cell hemoglobin concentration homozygote Female decreased mean corpuscular hemoglobin concentration 2.159653204042587E-30
Etaa1
Etaa1em1(IMPC)Marc
Hematology Eosinophil differential count homozygote Male increased eosinophil cell number 8.71543259451071E-30
Suv39h2
Suv39h2em1(IMPC)Marc
Hematology Basophil differential count homozygote Male increased basophil cell number 1.8648576526077783E-29
Hectd4
Hectd4em1(IMPC)Marc
Hematology Basophil cell count heterozygote Female increased basophil cell number 1.972478768363414E-29
Brix1
Brix1tm1b(KOMP)Mbp
Hematology Eosinophil differential count heterozygote Female increased eosinophil cell number 2.7025109397269024E-29
Erich2
Erich2em1(IMPC)Marc
Hematology Basophil differential count homozygote Male increased basophil cell number 3.625697032625417E-29
Fbxo36
Fbxo36tm1b(KOMP)Wtsi
Hematology Mean cell volume homozygote Male decreased mean corpuscular volume 4.543688230425501E-29
Hectd4
Hectd4em1(IMPC)Marc
Hematology Basophil cell count heterozygote Male increased basophil cell number 5.787357492013559E-29
Suv39h2
Suv39h2em1(IMPC)Marc
Hematology Basophil differential count homozygote Female increased basophil cell number 1.2271208289115318E-28
Spata16
Spata16em1(IMPC)Marc
Hematology Basophil differential count homozygote Male increased basophil cell number 1.2490383931611446E-28
Otud1
Otud1em1(IMPC)Marc
Open Field Latency to center entry homozygote Male decreased exploration in new environment 1.2953529157225258E-28
Hnrnpr
Hnrnprem1(IMPC)Marc
Hematology Mean cell volume homozygote Male increased mean corpuscular volume 2.627799482915193E-28
Otud6a
Otud6atm1(KOMP)Vlcg
Hematology Basophil differential count homozygote Male increased basophil cell number 3.365046669332842E-28
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) BMC/Body weight homozygote Female decreased bone mineral content 4.759763486823031E-28
Suv39h2
Suv39h2em1(IMPC)Marc
Hematology Eosinophil differential count homozygote Male increased eosinophil cell number 4.85100393645589E-28
Ces2e
Ces2eem1(IMPC)Marc
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 8.902069981615625E-28
Spata16
Spata16em1(IMPC)Marc
Hematology Eosinophil cell count homozygote Female increased eosinophil cell number 3.948374016077549E-27
Usp15
Usp15em1(IMPC)Marc
Hematology Basophil cell count homozygote Female increased basophil cell number 1.1036194108549088E-26
Kdm1a
Kdm1atm1(NCOM)Mfgc
Hematology Basophil differential count heterozygote Female increased basophil cell number 1.1067052128490038E-26
Zswim1
Zswim1tm1b(KOMP)Mbp
Hematology Neutrophil cell count homozygote Male increased neutrophil cell number 1.1938553917252728E-26
Etaa1
Etaa1em1(IMPC)Marc
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 4.478187405979965E-26
Hnrnph1
Hnrnph1tm1b(KOMP)Wtsi
Hematology Mean cell volume heterozygote Male increased mean corpuscular volume 6.162071713486062E-26
Fbxo36
Fbxo36tm1b(KOMP)Wtsi
Hematology Mean cell volume homozygote Female decreased mean corpuscular volume 7.422676370409896E-26
Hnrnpr
Hnrnprem1(IMPC)Marc
Hematology Mean cell volume homozygote Female increased mean corpuscular volume 8.996458806706472E-26
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration homozygote Male increased fasting circulating glucose level 1.6258817687057664E-25
Usp46
Usp46em1(IMPC)Marc
Hematology Basophil differential count homozygote Female increased basophil cell number 5.535632215009882E-25
Usp46
Usp46em1(IMPC)Marc
Hematology Basophil cell count homozygote Female increased basophil cell number 6.639356103712414E-25
Hnrnpd
Hnrnpdtm1b(KOMP)Wtsi
Hematology Basophil differential count heterozygote Male increased basophil cell number 8.45940809562928E-25
Fbxl19
Fbxl19tm1b(EUCOMM)Wtsi
Hematology Monocyte differential count heterozygote Male increased monocyte cell number 3.2709314769018192E-24
Fbxo43
Fbxo43em1(IMPC)Marc
Hematology Eosinophil cell count homozygote Female increased eosinophil cell number 6.684929584283163E-24
Hectd4
Hectd4em1(IMPC)Marc
Hematology Eosinophil differential count heterozygote Female increased eosinophil cell number 1.681836303801817E-23
Emc4
Emc4tm1(KOMP)Wtsi
Hematology Basophil differential count heterozygote Male increased basophil cell number 4.311587750612013E-23
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Fat/Body weight homozygote Female increased total body fat amount 6.029548519618797E-23
Atg4a
Atg4aem2(IMPC)Marc
Hematology Basophil cell count homozygote Female increased basophil cell number 1.1112476574746863E-22
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Lean/Body weight homozygote Female decreased lean body mass 1.8221649400742826E-22
Hnrnph1
Hnrnph1tm1b(KOMP)Wtsi
Hematology Mean cell volume heterozygote Female increased mean corpuscular volume 2.864851497207635E-22
Fbxo43
Fbxo43em1(IMPC)Marc
Hematology Basophil cell count homozygote Female increased basophil cell number 3.3146294406704056E-22
Usp32
Usp32em1(IMPC)Mhzh
Hematology Mean cell volume heterozygote Male increased mean corpuscular volume 4.707619969513352E-22
Otud1
Otud1em1(IMPC)Marc
Open Field Latency to center entry homozygote Female decreased exploration in new environment 5.191249512140967E-22
Usp36
Usp36tm1b(EUCOMM)Hmgu
Clinical Chemistry Glucose heterozygote Male increased circulating glucose level 1.1970211221663166E-21
Itprid1
Itprid1em1(IMPC)Marc
Hematology Basophil cell count homozygote Male increased basophil cell number 1.2280153535364798E-21
Fbxw8
Fbxw8tm1b(EUCOMM)Hmgu
Hematology Eosinophil differential count heterozygote Male increased eosinophil cell number 1.3952950629152486E-21
Suv39h2
Suv39h2em1(IMPC)Marc
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 1.4499793552490506E-21
Spata16
Spata16em1(IMPC)Marc
Hematology Basophil cell count homozygote Female increased basophil cell number 2.163366491923134E-21
Fbxo15
Fbxo15em1(IMPC)Marc
Hematology Neutrophil cell count homozygote Male increased neutrophil cell number 3.2332181874580303E-21
Usp26
Usp26em1(IMPC)Marc
Hematology Eosinophil cell count hemizygote increased eosinophil cell number 4.0818818679756035E-21
Ezh1
Ezh1tm1b(EUCOMM)Wtsi
Clinical Chemistry Glucose homozygote Female increased circulating glucose level 7.185191299842502E-21
Usp26
Usp26em1(IMPC)Marc
Hematology Basophil cell count hemizygote increased basophil cell number 7.842554317577808E-21
Hectd1
Hectd1tm1b(EUCOMM)Hmgu
Hematology Eosinophil cell count heterozygote Male increased eosinophil cell number 8.377235302920275E-21
Hectd3
Hectd3tm1(NCOM)Cmhd
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) homozygote Female decreased bone mineral density 1.0851001319703933E-20
Atg4a
Atg4aem2(IMPC)Marc
Hematology Basophil differential count homozygote Female increased basophil cell number 1.31784395708031E-20
Ash1l
Ash1ltm2b(EUCOMM)Hmgu
Hematology Basophil cell count heterozygote Male increased basophil cell number 1.3411166513027468E-20
Hectd1
Hectd1tm1b(EUCOMM)Hmgu
Hematology Eosinophil differential count heterozygote Male increased eosinophil cell number 1.5345347429723727E-20
Fbxo43
Fbxo43em1(IMPC)Marc
Hematology Basophil differential count homozygote Male increased basophil cell number 3.607230930649758E-20
Usp45
Usp45em1(IMPC)Marc
Hematology Basophil cell count homozygote Male increased basophil cell number 4.1849425946273153E-20
Usp26
Usp26em1(IMPC)Marc
Hematology Eosinophil differential count hemizygote increased eosinophil cell number 4.537725432358378E-20
Suv39h2
Suv39h2em1(IMPC)Marc
Hematology Eosinophil differential count homozygote Female increased eosinophil cell number 6.559354849437978E-20
Hnrnpdl
Hnrnpdlem1(IMPC)Marc
Hematology Basophil cell count homozygote Male increased basophil cell number 7.982528786858265E-20
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) homozygote Female decreased bone mineral density 1.7368666750945378E-19
Trim37
Trim37em1(IMPC)Marc
Body Composition (DEXA lean/fat) BMC/Body weight homozygote Female decreased bone mineral content 2.001924423924938E-19
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) homozygote Female decreased bone mineral content 2.619721066516359E-19
Fbxw8
Fbxw8tm1b(EUCOMM)Hmgu
Hematology Basophil differential count heterozygote Male increased basophil cell number 2.924010828577413E-19
Adarb1
Adarb1em1(IMPC)Marc
Hematology Mean cell volume heterozygote Female increased mean corpuscular volume 5.006390199300497E-19
Hnrnpr
Hnrnprem1(IMPC)Marc
Hematology Basophil differential count homozygote Male increased basophil cell number 5.975094693818871E-19
Hnrnpd
Hnrnpdtm1b(KOMP)Wtsi
Hematology Basophil cell count heterozygote Male increased basophil cell number 7.409117751207645E-19
Bap1
Bap1em2(IMPC)Marc
Hematology Basophil cell count heterozygote increased basophil cell number 8.853487804083691E-19
Hnrnph1
Hnrnph1tm1b(KOMP)Wtsi
Hematology Mean cell hemoglobin concentration heterozygote Male decreased mean corpuscular hemoglobin concentration 1.0753696413022398E-18
Pfkfb2
Pfkfb2tm1b(KOMP)Wtsi
Hematology Basophil cell count homozygote Male increased basophil cell number 1.0856456026544095E-18
Prmt6
Prmt6em1(IMPC)Marc
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 1.3209791073112053E-18
Zswim1
Zswim1tm1b(KOMP)Mbp
Hematology Mean cell volume homozygote Female decreased mean corpuscular volume 2.763345108358189E-18
Usp15
Usp15em1(IMPC)Marc
Hematology Eosinophil cell count homozygote Female increased eosinophil cell number 3.474442295672822E-18
Atg4c
Atg4cem2(IMPC)Marc
Hematology Eosinophil cell count homozygote Female increased eosinophil cell number 3.485102172226793E-18
Fbxl2
Fbxl2em2(IMPC)Marc
Hematology Mean cell volume homozygote Male increased mean corpuscular volume 4.525833935571104E-18
Hectd4
Hectd4em1(IMPC)Marc
Hematology Basophil differential count heterozygote Male increased basophil cell number 4.6519587130604334E-18
Atg4c
Atg4cem2(IMPC)Marc
Hematology Basophil cell count homozygote Female increased basophil cell number 5.294855065665222E-18
Ash1l
Ash1ltm2b(EUCOMM)Hmgu
Hematology Eosinophil cell count heterozygote Male increased eosinophil cell number 6.4611007336164925E-18
Usp31
Usp31em1(IMPC)Marc
Clinical Chemistry Phosphorus homozygote Female increased circulating phosphate level 7.532742582090685E-18
Fbxw8
Fbxw8tm1b(EUCOMM)Hmgu
Hematology Eosinophil cell count heterozygote Male increased eosinophil cell number 8.628420231214138E-18
Fbxo38
Fbxo38em2(IMPC)Marc
Hematology Red blood cell distribution width homozygote Male increased red blood cell distribution width 8.889239377338846E-18
Ppp2r5e
Ppp2r5eem1(IMPC)Marc
Hematology Mean cell volume homozygote Male increased mean corpuscular volume 1.0829264118267639E-17
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Fat mass homozygote Female increased total body fat amount 1.329577194829357E-17
Hnrnpr
Hnrnprem1(IMPC)Marc
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 1.9516800466319104E-17
Fbxo28
Fbxo28em1(IMPC)Mhzh
Hematology Eosinophil cell count heterozygote Male increased eosinophil cell number 4.336015589170702E-17
Kdm1a
Kdm1atm1(NCOM)Mfgc
Hematology Basophil differential count heterozygote Male increased basophil cell number 4.666703207479191E-17
Fbxo43
Fbxo43em1(IMPC)Marc
Hematology Eosinophil differential count homozygote Male increased eosinophil cell number 4.929515693444029E-17
Usp15
Usp15em1(IMPC)Marc
Hematology Basophil differential count homozygote Female increased basophil cell number 5.716033761445175E-17
Kdm1a
Kdm1atm1(NCOM)Mfgc
Hematology Basophil cell count heterozygote Male increased basophil cell number 7.102931760310374E-17
Ppp2r5e
Ppp2r5eem1(IMPC)Marc
Hematology Mean cell volume homozygote Female increased mean corpuscular volume 8.475198588500736E-17
AW112010
AW112010em1(IMPC)Marc
Hematology Mean cell volume homozygote Male decreased mean corpuscular volume 9.70198353753323E-17
Itprid1
Itprid1em1(IMPC)Marc
Hematology Basophil differential count homozygote Male increased basophil cell number 9.729788717515833E-17
Ube2z
Ube2zem1(IMPC)Marc
Hematology Eosinophil differential count heterozygote Male increased eosinophil cell number 1.1363142863785492E-16
Itprid1
Itprid1em1(IMPC)Marc
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 1.166729386629879E-16
Etaa1
Etaa1em1(IMPC)Marc
Hematology Eosinophil cell count homozygote Female increased eosinophil cell number 1.327245571205917E-16
Erich2
Erich2em1(IMPC)Marc
Hematology Eosinophil differential count homozygote Female increased eosinophil cell number 1.3592479317910627E-16
Ces2e
Ces2eem1(IMPC)Marc
Hematology Mean cell volume homozygote Female decreased mean corpuscular volume 1.3751996797702293E-16
Usp26
Usp26em1(IMPC)Marc
Hematology Basophil differential count hemizygote increased basophil cell number 1.664402668346857E-16
Bbc3
Bbc3em1(IMPC)Marc
Hematology Mean cell hemoglobin concentration homozygote Female increased mean corpuscular hemoglobin concentration 1.7049396799689778E-16
Fbxo28
Fbxo28em1(IMPC)Mhzh
Hematology Eosinophil differential count heterozygote Male increased eosinophil cell number 2.0088634394243953E-16
Adarb1
Adarb1em1(IMPC)Marc
Hematology Mean cell hemoglobin concentration heterozygote Female decreased mean corpuscular hemoglobin concentration 2.3631036029246784E-16
Brix1
Brix1tm1b(KOMP)Mbp
Hematology Eosinophil cell count heterozygote Female increased eosinophil cell number 2.410440568577577E-16
Prdm2
Prdm2em1(IMPC)Marc
Hematology Basophil cell count homozygote Male increased basophil cell number 2.9503301047346074E-16
Atg4c
Atg4cem2(IMPC)Marc
Hematology Eosinophil differential count homozygote Female increased eosinophil cell number 3.4260690712357414E-16
Atp13a5
Atp13a5em1(IMPC)Marc
Hematology Eosinophil differential count homozygote Female increased eosinophil cell number 3.7099860448259103E-16
Fbxo28
Fbxo28em1(IMPC)Mhzh
Hematology Basophil cell count heterozygote Male increased basophil cell number 3.7772341080907974E-16
Usp45
Usp45em1(IMPC)Marc
Hematology Basophil differential count homozygote Male increased basophil cell number 3.895064596685547E-16
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration homozygote Female increased fasting circulating glucose level 4.06333192682235E-16
Ash1l
Ash1ltm2b(EUCOMM)Hmgu
Hematology Basophil differential count heterozygote Female increased basophil cell number 4.611636470612556E-16
Hnrnph1
Hnrnph1tm1b(KOMP)Wtsi
Hematology Mean cell hemoglobin concentration heterozygote Female decreased mean corpuscular hemoglobin concentration 5.590449745009496E-16
Prmt6
Prmt6em1(IMPC)Marc
Hematology Eosinophil differential count homozygote Male increased eosinophil cell number 7.913284078132725E-16
Hectd3
Hectd3tm1(NCOM)Cmhd
Body Composition (DEXA lean/fat) BMC/Body weight homozygote Female decreased bone mineral content 8.118601688173615E-16
Prdm2
Prdm2em1(IMPC)Marc
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 1.2893917746722408E-15
Atg4a
Atg4aem2(IMPC)Marc
Hematology Eosinophil cell count homozygote Female increased eosinophil cell number 1.9685145220561242E-15
Kdm1a
Kdm1atm1(NCOM)Mfgc
Hematology Eosinophil differential count heterozygote Male increased eosinophil cell number 2.01812714760094E-15
Hnrnpdl
Hnrnpdlem1(IMPC)Marc
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 2.0444146033607403E-15
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Lean/Body weight homozygote Male decreased lean body mass 2.3979341800509264E-15
Phf5a
Phf5aem2(IMPC)Marc
Hematology Mean cell volume heterozygote Female increased mean corpuscular volume 2.741370041262287E-15
Rbm11
Rbm11em1(IMPC)Marc
Hematology Basophil cell count homozygote Female increased basophil cell number 2.911435198829637E-15
Fbxw8
Fbxw8tm1b(EUCOMM)Hmgu
Hematology Basophil cell count heterozygote Male increased basophil cell number 3.597966414007562E-15
Rbm11
Rbm11em1(IMPC)Marc
Hematology Basophil cell count homozygote Male increased basophil cell number 4.653293233321167E-15
Phf5a
Phf5aem2(IMPC)Marc
Hematology Mean platelet volume heterozygote Female increased mean platelet volume 4.999748343473016E-15
Emc4
Emc4tm1(KOMP)Wtsi
Hematology Eosinophil differential count heterozygote Male increased eosinophil cell number 5.658150865022046E-15
Spata16
Spata16em1(IMPC)Marc
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 6.305617344189076E-15
Atg4c
Atg4cem2(IMPC)Marc
Hematology Basophil differential count homozygote Female increased basophil cell number 9.508193013583067E-15
Fbxo38
Fbxo38em2(IMPC)Marc
Hematology Red blood cell distribution width homozygote Female increased red blood cell distribution width 1.3174936808841783E-14
Suv39h2
Suv39h2em1(IMPC)Marc
Hematology Basophil cell count homozygote Female increased basophil cell number 1.339974104710897E-14
Brcc3
Brcc3em1(IMPC)Marc
Hematology Basophil differential count homozygote Male increased basophil cell number 1.4196690630258017E-14
Spata16
Spata16em1(IMPC)Marc
Hematology Basophil cell count homozygote Male increased basophil cell number 1.4497726139712196E-14
Phf5a
Phf5aem2(IMPC)Marc
Body Composition (DEXA lean/fat) BMC/Body weight heterozygote Male increased bone mineral content 1.4585199232175147E-14
Ctsm
Ctsmtm1(KOMP)Wtsi
Hematology Mean cell volume homozygote Male decreased mean corpuscular volume 1.5481910661785912E-14
Ube2e1
Ube2e1em1(IMPC)Marc
Hematology Hematocrit homozygote Female increased hematocrit 1.5862279277079928E-14
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Lean mass homozygote Female decreased lean body mass 1.713320478058996E-14
Rbm11
Rbm11em1(IMPC)Marc
Hematology Basophil differential count homozygote Female increased basophil cell number 1.7734388108969594E-14
Prdm2
Prdm2em1(IMPC)Marc
Hematology Mean corpuscular hemoglobin homozygote Female increased mean corpuscular hemoglobin 1.7740205531251337E-14
Prmt6
Prmt6em1(IMPC)Marc
Hematology Basophil differential count homozygote Male increased basophil cell number 1.7749856624652352E-14
Zswim1
Zswim1tm1b(KOMP)Mbp
Hematology Monocyte cell count homozygote Female increased monocyte cell number 2.016808317302065E-14
Adarb1
Adarb1em1(IMPC)Marc
Hematology Mean cell volume heterozygote Male increased mean corpuscular volume 2.4023634847387086E-14
Zswim1
Zswim1tm1b(KOMP)Mbp
Hematology Red blood cell distribution width homozygote Male increased red blood cell distribution width 2.53143097710953E-14
Aars2
Aars2tm1(KOMP)Wtsi
Hematology Eosinophil cell count heterozygote Male increased eosinophil cell number 2.535852319687608E-14
Otud6a
Otud6atm1(KOMP)Vlcg
Hematology Basophil cell count homozygote increased basophil cell number 2.925550155862683E-14
Prdm2
Prdm2em1(IMPC)Marc
Hematology Eosinophil differential count homozygote Male increased eosinophil cell number 3.057097760703065E-14
Ube2e1
Ube2e1em1(IMPC)Marc
Hematology Hematocrit homozygote Male increased hematocrit 3.065170662316756E-14
Atg4a
Atg4aem2(IMPC)Marc
Hematology Eosinophil differential count homozygote Female increased eosinophil cell number 3.6909121863427236E-14
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Combined SHIRPA and Dysmorphology Genitalia - size homozygote abnormal female genitalia morphology 6.671726837442424E-14
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Combined SHIRPA and Dysmorphology Genitalia - presence homozygote absent external male genitalia 6.671726837442424E-14
Fbxo36
Fbxo36tm1b(KOMP)Wtsi
Hematology Mean cell hemoglobin concentration homozygote Female increased mean corpuscular hemoglobin concentration 7.556420224784366E-14
Ash1l
Ash1ltm2b(EUCOMM)Hmgu
Hematology Basophil differential count heterozygote Male increased basophil cell number 8.666847892569579E-14
Hnrnpr
Hnrnprem1(IMPC)Marc
Hematology Eosinophil differential count homozygote Male increased eosinophil cell number 8.985728014530153E-14
Kdm1a
Kdm1atm1(NCOM)Mfgc
Hematology Basophil cell count heterozygote Female increased basophil cell number 9.69976391416473E-14
Ufc1
Ufc1em1(IMPC)Marc
Hematology Basophil differential count heterozygote Female increased basophil cell number 1.0708081421345259E-13
Ctsm
Ctsmtm1(KOMP)Wtsi
Hematology Mean cell volume homozygote Female decreased mean corpuscular volume 1.0743963769870024E-13
Trim37
Trim37em1(IMPC)Marc
Intraperitoneal glucose tolerance test (IPGTT) Area under glucose response curve homozygote Male improved glucose tolerance 1.0865806410013945E-13
Zswim1
Zswim1tm1b(KOMP)Mbp
Hematology Neutrophil differential count homozygote Male increased neutrophil cell number 1.162917147561754E-13
Trim37
Trim37em1(IMPC)Marc
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) homozygote Female decreased bone mineral density 1.2822459294434957E-13
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Combined SHIRPA and Dysmorphology Genitalia - morphology homozygote abnormal male genitalia morphology 1.3745441959124582E-13
Fbxo15
Fbxo15em1(IMPC)Marc
Hematology Lymphocyte differential count homozygote Male decreased lymphocyte cell number 1.411058905354326E-13
Phf5a
Phf5aem2(IMPC)Marc
Hematology Mean cell volume heterozygote Male increased mean corpuscular volume 1.562074308878586E-13
Psmd14
Psmd14tm1b(NCOM)Cmhd
Hematology Basophil cell count heterozygote Male increased basophil cell number 1.6311313465276062E-13
Ufm1
Ufm1em1(IMPC)Marc
Body Composition (DEXA lean/fat) Fat mass heterozygote Male increased total body fat amount 1.7501424571728097E-13
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Fat/Body weight homozygote Male increased total body fat amount 1.8057000935722128E-13
Aars2
Aars2tm1(KOMP)Wtsi
Hematology Eosinophil differential count heterozygote Male increased eosinophil cell number 2.050715825450966E-13
Fbxl2
Fbxl2em2(IMPC)Marc
Hematology Mean cell hemoglobin concentration homozygote Male decreased mean corpuscular hemoglobin concentration 2.392306188217508E-13
Fbxo15
Fbxo15em1(IMPC)Marc
Hematology Neutrophil differential count homozygote Male increased neutrophil cell number 3.5841259972933803E-13
Fam166b
Fam166btm1(KOMP)Wtsi
Hematology Basophil differential count homozygote Male increased basophil cell number 3.6635397406697967E-13
Usp47
Usp47tm1b(EUCOMM)Wtsi
Clinical Chemistry HDL-cholesterol homozygote Male increased circulating HDL cholesterol level 3.821924330835169E-13
Ube2z
Ube2zem1(IMPC)Marc
Hematology Eosinophil differential count heterozygote Female increased eosinophil cell number 3.839037106875137E-13
Ezh1
Ezh1tm1b(EUCOMM)Wtsi
Clinical Chemistry Glucose homozygote Male increased circulating glucose level 4.335936449294253E-13
Fbxo10
Fbxo10tm1b(KOMP)Wtsi
Hematology Mean corpuscular hemoglobin homozygote Male decreased mean corpuscular hemoglobin 5.201075572829061E-13
Brcc3
Brcc3em1(IMPC)Marc
Hematology Eosinophil differential count homozygote Male increased eosinophil cell number 5.218828841302425E-13
Rbm11
Rbm11em1(IMPC)Marc
Hematology Eosinophil differential count homozygote Female increased eosinophil cell number 5.546127793132349E-13
Ube2w
Ube2wtm1b(EUCOMM)Wtsi
Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration homozygote Male increased fasting circulating glucose level 6.787734979120386E-13
Fbxo10
Fbxo10tm1b(KOMP)Wtsi
Clinical Chemistry Triglycerides homozygote Male decreased circulating triglyceride level 6.865202850647734E-13
Brcc3
Brcc3em1(IMPC)Marc
Hematology Mean cell volume homozygote Female increased mean corpuscular volume 7.19683427435891E-13
Hnrnpdl
Hnrnpdlem1(IMPC)Marc
Hematology Basophil differential count homozygote Male increased basophil cell number 7.767296463130624E-13
Usp31
Usp31em1(IMPC)Marc
Hematology Hematocrit homozygote Female decreased hematocrit 8.996123616010487E-13
Pfkfb2
Pfkfb2tm1b(KOMP)Wtsi
Hematology Basophil differential count homozygote Male increased basophil cell number 1.1277167350984274E-12
Prmt6
Prmt6em1(IMPC)Marc
Hematology Basophil cell count homozygote Male increased basophil cell number 1.1605593873073583E-12
Cyld
Cyldem2(IMPC)Marc
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 1.3487884854140875E-12
Hectd3
Hectd3tm1(NCOM)Cmhd
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) homozygote Female decreased bone mineral content 1.3566803930276095E-12
Gsdma3
Gsdma3tm1(KOMP)Vlcg
Hematology Mean corpuscular hemoglobin homozygote Male increased mean corpuscular hemoglobin 1.367690574509417E-12
Etaa1
Etaa1em1(IMPC)Marc
Hematology Eosinophil differential count homozygote Female increased eosinophil cell number 1.4979156153296924E-12
Adarb1
Adarb1em1(IMPC)Marc
Hematology Mean cell hemoglobin concentration heterozygote Male decreased mean corpuscular hemoglobin concentration 1.5250929859267348E-12
Fbxo10
Fbxo10tm1b(KOMP)Wtsi
Hematology Mean cell volume homozygote Female decreased mean corpuscular volume 1.7588839456086913E-12
Gsdma3
Gsdma3tm1(KOMP)Vlcg
Hematology Mean cell hemoglobin concentration homozygote Male increased mean corpuscular hemoglobin concentration 1.911127289408454E-12
Fbxo15
Fbxo15em1(IMPC)Marc
Hematology Eosinophil differential count homozygote Female increased eosinophil cell number 2.0338594090146822E-12
Usp47
Usp47tm1b(EUCOMM)Wtsi
Clinical Chemistry Total cholesterol homozygote Male increased circulating cholesterol level 2.108181684778998E-12
Usp46
Usp46em1(IMPC)Marc
Hematology Eosinophil cell count homozygote Female increased eosinophil cell number 2.1634380484997218E-12
Hectd4
Hectd4em1(IMPC)Marc
Hematology Eosinophil cell count heterozygote Male increased eosinophil cell number 2.19517589869489E-12
Hnrnpr
Hnrnprem1(IMPC)Marc
Hematology Lymphocyte cell count homozygote Female increased lymphocyte cell number 2.2055844563911853E-12
Cyld
Cyldem2(IMPC)Marc
Hematology Basophil differential count homozygote Male increased basophil cell number 2.6170903551919755E-12
Trim37
Trim37em1(IMPC)Marc
Body Composition (DEXA lean/fat) Fat/Body weight homozygote Female increased total body fat amount 2.7133308620752583E-12
Zswim1
Zswim1tm1b(KOMP)Mbp
Hematology Mean cell volume homozygote Male decreased mean corpuscular volume 3.4115061036538163E-12
Eddm3b
Eddm3btm1b(KOMP)Wtsi
Hematology Basophil cell count homozygote increased basophil cell number 4.013622333792766E-12
Rbm11
Rbm11em1(IMPC)Marc
Hematology Eosinophil differential count homozygote Male increased eosinophil cell number 4.4550847386193304E-12
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Lean mass homozygote Male decreased lean body mass 5.349229739715078E-12
Usp46
Usp46em1(IMPC)Marc
Hematology Eosinophil differential count homozygote Female increased eosinophil cell number 6.415296245620983E-12
Etaa1
Etaa1em1(IMPC)Marc
Hematology Red blood cell distribution width homozygote Male increased red blood cell distribution width 8.146300474465296E-12
Cpa1
Cpa1em1(IMPC)Marc
Hematology Lymphocyte cell count homozygote Male increased lymphocyte cell number 9.415334831230915E-12
Otud6a
Otud6atm1(KOMP)Vlcg
Hematology Eosinophil differential count homozygote Male increased eosinophil cell number 1.045046427866625E-11
Fbxo36
Fbxo36tm1b(KOMP)Wtsi
Hematology Mean cell hemoglobin concentration homozygote Male increased mean corpuscular hemoglobin concentration 1.0580396801740388E-11
Lhcgr
Lhcgrtm1(KOMP)Vlcg
Hematology White blood cell count homozygote Male increased leukocyte cell number 1.0758796631371581E-11
Fbxo10
Fbxo10tm1b(KOMP)Wtsi
Clinical Chemistry Urea (Blood Urea Nitrogen - BUN) homozygote Male decreased blood urea nitrogen level 1.204197418863684E-11
Esr2
Esr2em1(IMPC)Marc
Body Composition (DEXA lean/fat) Fat/Body weight homozygote Male increased total body fat amount 1.327294784497779E-11
Fancl
Fancltm1b(EUCOMM)Hmgu
Hematology Eosinophil differential count homozygote Female increased eosinophil cell number 1.3856750816221286E-11
Cyld
Cyldem2(IMPC)Marc
Open Field Periphery resting time homozygote Female decreased locomotor activity 1.4298748816921059E-11
Ankle1
Ankle1tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Coat - color - head homozygote Female abnormal coat/hair pigmentation 1.6593728127678453E-11
Cox8a
Cox8aem1(IMPC)Marc
Clinical Chemistry Triglycerides homozygote Male increased circulating triglyceride level 1.688901102303575E-11
Cyld
Cyldem2(IMPC)Marc
Open Field Periphery average speed homozygote Female decreased locomotor activity 1.7281925890344496E-11
Phf5a
Phf5aem2(IMPC)Marc
Body Composition (DEXA lean/fat) BMC/Body weight heterozygote Female increased bone mineral content 1.7606459692953713E-11
Rbm11
Rbm11em1(IMPC)Marc
Hematology Eosinophil cell count homozygote Female increased eosinophil cell number 1.7739870336597185E-11
Dlgap2
Dlgap2em1(IMPC)Mhzh
Hematology Neutrophil differential count homozygote Male increased neutrophil cell number 1.8359227332842565E-11
Zdhhc2
Zdhhc2tm1b(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Lower lip morphology homozygote Male abnormal lip morphology 1.9377477053494907E-11
Fshr
Fshrtm1(KOMP)Vlcg
Body Composition (DEXA lean/fat) BMC/Body weight homozygote Female decreased bone mineral content 1.98331177869715E-11
Ankle1
Ankle1tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Coat - color - abdomen homozygote Female abnormal coat/hair pigmentation 2.342643960762114E-11
Fbxo36
Fbxo36tm1b(KOMP)Wtsi
Hematology Mean platelet volume homozygote Male decreased mean platelet volume 2.7548964845469648E-11
Kdm1a
Kdm1atm1(NCOM)Mfgc
Hematology Eosinophil differential count heterozygote Female increased eosinophil cell number 2.7630477766882322E-11
Usp31
Usp31em1(IMPC)Marc
Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI1 homozygote Male increased prepulse inhibition 2.843287584541887E-11
Fbxo43
Fbxo43em1(IMPC)Marc
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 2.9192842587733026E-11
Esr2
Esr2em1(IMPC)Marc
Body Composition (DEXA lean/fat) Lean/Body weight homozygote Male decreased lean body mass 3.3062021870255975E-11
Ash1l
Ash1ltm2b(EUCOMM)Hmgu
Eye Morphology Pupil Light Response heterozygote Female impaired pupillary reflex 3.512077087486354E-11
Zswim1
Zswim1tm1b(KOMP)Mbp
Hematology Lymphocyte differential count homozygote Male decreased lymphocyte cell number 3.702719381104558E-11
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) homozygote Male decreased bone mineral density 3.776940912803006E-11
Fbxo2
Fbxo2tm1b(EUCOMM)Wtsi
Clinical Chemistry Glucose homozygote Female increased circulating glucose level 3.8915305006215206E-11
Rbm11
Rbm11em1(IMPC)Marc
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 4.1465088307379716E-11
Atg4b
Atg4bem1(IMPC)Marc
Clinical Chemistry Urea (Blood Urea Nitrogen - BUN) homozygote Male decreased blood urea nitrogen level 4.202541786790803E-11
Dlgap2
Dlgap2em1(IMPC)Mhzh
Hematology Eosinophil cell count homozygote increased eosinophil cell number 4.46609901838535E-11
Hectd3
Hectd3tm1(NCOM)Cmhd
Grip Strength Forelimb and hindlimb grip strength measurement mean homozygote Male decreased grip strength 4.6738442976979044E-11
Ufc1
Ufc1em1(IMPC)Marc
Hematology Basophil cell count heterozygote increased basophil cell number 4.780797979719864E-11
Fancl
Fancltm1b(EUCOMM)Hmgu
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) homozygote Female decreased bone mineral content 4.9669799523366365E-11
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Bone Area homozygote Female abnormal bone structure 5.219737836403837E-11
Vav2
Vav2em1(IMPC)Marc
Hematology Basophil cell count homozygote Male increased basophil cell number 5.66362338971782E-11
Atg4c
Atg4cem2(IMPC)Marc
Hematology Neutrophil cell count homozygote Male increased neutrophil cell number 6.261693247244793E-11
Dlgap2
Dlgap2em1(IMPC)Mhzh
Hematology Lymphocyte differential count homozygote Male decreased lymphocyte cell number 6.541472225007894E-11
Usp15
Usp15em1(IMPC)Marc
Hematology Basophil differential count homozygote Male increased basophil cell number 6.607826785742787E-11
Dlgap2
Dlgap2em1(IMPC)Mhzh
Hematology Neutrophil cell count homozygote Male increased neutrophil cell number 6.677599445614746E-11
Ufm1
Ufm1em1(IMPC)Marc
Body Composition (DEXA lean/fat) Fat/Body weight heterozygote Male increased total body fat amount 7.345675456793543E-11
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Open Field Periphery resting time homozygote Female decreased locomotor activity 7.495190579298594E-11
Bap1
Bap1em2(IMPC)Marc
Hematology Basophil differential count heterozygote Female increased basophil cell number 8.351216246316184E-11
Hectd4
Hectd4em1(IMPC)Marc
Hematology Eosinophil differential count heterozygote Male increased eosinophil cell number 8.911409110634594E-11
Cyld
Cyldem2(IMPC)Marc
Open Field Whole arena resting time homozygote Female decreased locomotor activity 9.13792097545496E-11
Emc4
Emc4tm1(KOMP)Wtsi
Hematology Basophil cell count heterozygote increased basophil cell number 9.939920414536729E-11
Trim37
Trim37em1(IMPC)Marc
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) homozygote Female decreased bone mineral content 9.946409668115663E-11
Prdm2
Prdm2em1(IMPC)Marc
Hematology Mean corpuscular hemoglobin homozygote Male increased mean corpuscular hemoglobin 1.0705081959772045E-10
Ctsm
Ctsmtm1(KOMP)Wtsi
Hematology Monocyte differential count homozygote Male increased monocyte cell number 1.1216463868812809E-10
Cdc42ep5
Cdc42ep5tm1(KOMP)Wtsi
Hematology Eosinophil differential count homozygote Male increased eosinophil cell number 1.1777662178857895E-10
Ankrd65
Ankrd65tm1(KOMP)Wtsi
Open Field Latency to center entry homozygote Male decreased exploration in new environment 1.2999898379995045E-10
Ppp2r2a
Ppp2r2atm1b(KOMP)Wtsi
Body Composition (DEXA lean/fat) Lean mass heterozygote Male decreased lean body mass 1.329385490578261E-10
Ankle1
Ankle1tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Coat - color - back homozygote Female abnormal coat/hair pigmentation 1.3779541396807815E-10
Hnrnpr
Hnrnprem1(IMPC)Marc
Hematology Hematocrit homozygote Female increased hematocrit 1.3795437014962886E-10
Bbc3
Bbc3em1(IMPC)Marc
Hematology Mean cell hemoglobin concentration homozygote Male increased mean corpuscular hemoglobin concentration 1.4424290928349848E-10
Ces2e
Ces2eem1(IMPC)Marc
Hematology Mean corpuscular hemoglobin homozygote Female decreased mean corpuscular hemoglobin 1.4879224241592937E-10
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Fat mass homozygote Male increased total body fat amount 1.489402212673241E-10
Zswim1
Zswim1tm1b(KOMP)Mbp
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 1.5396355024233088E-10
Fancl
Fancltm1b(EUCOMM)Hmgu
Hematology Basophil cell count homozygote Female increased basophil cell number 1.5781256856861603E-10
Cdc42ep5
Cdc42ep5tm1(KOMP)Wtsi
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 1.6263806967842243E-10
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Open Field Whole arena resting time homozygote Female decreased locomotor activity 1.8973708715286364E-10
Hectd4
Hectd4em1(IMPC)Marc
Hematology Eosinophil cell count heterozygote Female increased eosinophil cell number 1.936969612481576E-10
Prdm2
Prdm2em1(IMPC)Marc
Hematology Basophil differential count homozygote Male increased basophil cell number 1.9681571650220775E-10
Cpa1
Cpa1em1(IMPC)Marc
Hematology Mean corpuscular hemoglobin homozygote Female increased mean corpuscular hemoglobin 1.971008495305071E-10
Fbxl2
Fbxl2em2(IMPC)Marc
Hematology Mean corpuscular hemoglobin homozygote Female increased mean corpuscular hemoglobin 2.0295559677308006E-10
Apbb3
Apbb3em1(IMPC)Marc
Hematology Basophil differential count homozygote Female increased basophil cell number 2.259569059637201E-10
Bbc3
Bbc3em1(IMPC)Marc
Hematology Mean corpuscular hemoglobin homozygote Female increased mean corpuscular hemoglobin 2.411409405489451E-10
Fbxw13
Fbxw13em2(IMPC)Marc
Hematology Mean cell volume homozygote Female increased mean corpuscular volume 2.4206611715094084E-10
Ufc1
Ufc1em1(IMPC)Marc
Hematology Eosinophil differential count heterozygote Female increased eosinophil cell number 2.422804179502691E-10
Apbb3
Apbb3em1(IMPC)Marc
Hematology Basophil cell count homozygote Female increased basophil cell number 2.8735722135131425E-10
Fancl
Fancltm1b(EUCOMM)Hmgu
Body Composition (DEXA lean/fat) BMC/Body weight homozygote Female decreased bone mineral content 2.9872540552311477E-10
Cyld
Cyldem2(IMPC)Marc
Open Field Distance travelled - total homozygote Female decreased locomotor activity 3.108718282796019E-10
Zswim1
Zswim1tm1b(KOMP)Mbp
Hematology Mean platelet volume homozygote Male increased mean platelet volume 3.1381247600492657E-10
Bod1
Bod1tm1b(KOMP)Wtsi
Hematology Eosinophil cell count heterozygote Female increased eosinophil cell number 3.155044558944553E-10
Fbxl19
Fbxl19tm1b(EUCOMM)Wtsi
Hematology Lymphocyte differential count heterozygote Male decreased lymphocyte cell number 3.447233054565402E-10
Eddm3b
Eddm3btm1b(KOMP)Wtsi
Eye Morphology Iris Pigmentation homozygote Male abnormal iris pigmentation 3.5388308949890757E-10
Usp15
Usp15em1(IMPC)Marc
Hematology Eosinophil differential count homozygote Female increased eosinophil cell number 3.573746021334756E-10
Ash1l
Ash1ltm2b(EUCOMM)Hmgu
Hematology Basophil cell count heterozygote Female increased basophil cell number 3.818070581917965E-10
Zswim1
Zswim1tm1b(KOMP)Mbp
Hematology White blood cell count homozygote Female increased leukocyte cell number 3.9608599733398364E-10
Esr2
Esr2em1(IMPC)Marc
Body Composition (DEXA lean/fat) Fat mass homozygote Male increased total body fat amount 4.200962910871908E-10
Fam166b
Fam166btm1(KOMP)Wtsi
Hematology Basophil cell count homozygote increased basophil cell number 4.64419863677179E-10
AW112010
AW112010em1(IMPC)Marc
Hematology Mean corpuscular hemoglobin homozygote Male decreased mean corpuscular hemoglobin 4.75263550736571E-10
Alg1
Alg1tm1b(KOMP)Wtsi
Hematology Eosinophil differential count heterozygote Female increased eosinophil cell number 4.812816256638541E-10
Hnrnpr
Hnrnprem1(IMPC)Marc
Hematology White blood cell count homozygote Female increased leukocyte cell number 4.946920650894526E-10
Hectd1
Hectd1tm1b(EUCOMM)Hmgu
Clinical Chemistry Calcium heterozygote Female increased circulating calcium level 5.151917226164926E-10
Fancl
Fancltm1b(EUCOMM)Hmgu
Hematology Eosinophil cell count homozygote Female increased eosinophil cell number 5.231832744811982E-10
Fbxo43
Fbxo43em1(IMPC)Marc
Hematology Basophil cell count homozygote Male increased basophil cell number 5.298748662063701E-10
Fbxo22
Fbxo22tm1b(EUCOMM)Wtsi
Combined SHIRPA and Dysmorphology Tail - morphology homozygote Female abnormal tail morphology 5.340325959224401E-10
Zfp36
Zfp36tm1(KOMP)Vlcg
Hematology Mean cell volume heterozygote Male decreased mean corpuscular volume 5.640804490170126E-10
Atp13a5
Atp13a5em1(IMPC)Marc
Hematology Basophil differential count homozygote Female increased basophil cell number 5.780683709488699E-10
Suv39h2
Suv39h2em1(IMPC)Marc
Hematology Eosinophil cell count homozygote Female increased eosinophil cell number 6.026235066514118E-10
Erich2
Erich2em1(IMPC)Marc
Hematology Eosinophil cell count homozygote Female increased eosinophil cell number 6.152171549977936E-10
Ccdc83
Ccdc83em1(IMPC)Marc
Hematology Lymphocyte cell count homozygote Female decreased lymphocyte cell number 6.570474164746543E-10
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Grip Strength Forelimb and hindlimb grip strength normalised against body weight homozygote Female decreased grip strength 7.879936148036393E-10
Ash1l
Ash1ltm2b(EUCOMM)Hmgu
Heart Weight Heart weight heterozygote Male increased heart weight 9.528856592666557E-10
Vav2
Vav2em1(IMPC)Marc
Hematology Eosinophil differential count homozygote Male increased eosinophil cell number 1.0167769959323891E-9
Ccdc124
Ccdc124tm1b(KOMP)Wtsi
Open Field Latency to center entry homozygote Female decreased exploration in new environment 1.042132380391081E-9
Atp13a5
Atp13a5em1(IMPC)Marc
Hematology Basophil cell count homozygote increased basophil cell number 1.1246419351351733E-9
Trim37
Trim37em1(IMPC)Marc
Body Composition (DEXA lean/fat) Lean/Body weight homozygote Female decreased lean body mass 1.2798783144418735E-9
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Open Field Periphery resting time heterozygote Female decreased locomotor activity 1.2800535076351593E-9
Fbxo36
Fbxo36tm1b(KOMP)Wtsi
Hematology Hematocrit homozygote Male decreased hematocrit 1.2821612660474102E-9
Cyld
Cyldem2(IMPC)Marc
Hematology Eosinophil differential count homozygote Male increased eosinophil cell number 1.3019286759785587E-9
Fancl
Fancltm1b(EUCOMM)Hmgu
Hematology Basophil differential count homozygote Female increased basophil cell number 1.3090530881498808E-9
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Open Field Whole arena resting time heterozygote Male decreased locomotor activity 1.4854438790123936E-9
Rbm11
Rbm11em1(IMPC)Marc
Hematology Basophil differential count homozygote Male increased basophil cell number 1.6899114330115594E-9
Fbxo28
Fbxo28em1(IMPC)Mhzh
Hematology Basophil differential count heterozygote Male increased basophil cell number 1.7720341860538724E-9
Ufm1
Ufm1em1(IMPC)Marc
Body Composition (DEXA lean/fat) BMC/Body weight heterozygote Male decreased bone mineral content 2.4165951462151725E-9
Ufm1
Ufm1em1(IMPC)Marc
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) heterozygote Male decreased bone mineral density 2.563832479651751E-9
B3galt1
B3galt1em1(IMPC)Marc
Hematology Mean platelet volume homozygote Female increased mean platelet volume 2.5985613660850504E-9
Ufm1
Ufm1em1(IMPC)Marc
Body Composition (DEXA lean/fat) Lean/Body weight heterozygote Male decreased lean body mass 2.754716676989233E-9
Hnrnpd
Hnrnpdtm1b(KOMP)Wtsi
Hematology Lymphocyte cell count heterozygote Female decreased lymphocyte cell number 3.2092137836059464E-9
Usp31
Usp31em1(IMPC)Marc
Clinical Chemistry Glucose homozygote Female increased circulating glucose level 3.2136975303131976E-9
Dlgap2
Dlgap2em1(IMPC)Mhzh
Hematology Eosinophil differential count homozygote Male increased eosinophil cell number 3.5158256306289104E-9
Usp45
Usp45em1(IMPC)Marc
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 3.5645739693279666E-9
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Open Field Periphery resting time heterozygote Male decreased locomotor activity 3.964859995875258E-9
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Open Field Whole arena resting time heterozygote Female decreased locomotor activity 4.015604293527986E-9
Usp15
Usp15em1(IMPC)Marc
Hematology Eosinophil differential count homozygote Male increased eosinophil cell number 4.120611407643082E-9
Hectd3
Hectd3tm1(NCOM)Cmhd
Body Composition (DEXA lean/fat) Bone Area homozygote Female abnormal bone structure 4.258501995479946E-9
Fbxo36
Fbxo36tm1b(KOMP)Wtsi
Hematology Hematocrit homozygote Female decreased hematocrit 4.346282889144959E-9
Usp32
Usp32em1(IMPC)Mhzh
Hematology Platelet count heterozygote Male thrombocytosis 4.6050030455546676E-9
Cyld
Cyldem2(IMPC)Marc
Open Field Whole arena average speed homozygote Female decreased locomotor activity 4.745963178010015E-9
Zswim1
Zswim1tm1b(KOMP)Mbp
Hematology White blood cell count homozygote Male increased leukocyte cell number 4.7888470966483965E-9
Fbxo38
Fbxo38em2(IMPC)Marc
Clinical Chemistry Aspartate aminotransferase homozygote Female increased circulating aspartate transaminase level 4.84226925223652E-9
Ces2f
Ces2ftm1b(KOMP)Wtsi
Hematology Red blood cell distribution width homozygote Male increased red blood cell distribution width 4.975945433471907E-9
Usp32
Usp32em1(IMPC)Mhzh
Hematology Lymphocyte cell count heterozygote Male increased lymphocyte cell number 5.040092787567119E-9
Adarb1
Adarb1em1(IMPC)Marc
Hematology Hematocrit heterozygote Female increased hematocrit 5.064535013588056E-9
Fancl
Fancltm1b(EUCOMM)Hmgu
Body Composition (DEXA lean/fat) Bone Area homozygote Female abnormal bone structure 5.108797385133812E-9
Ash1l
Ash1ltm2b(EUCOMM)Hmgu
Hematology Eosinophil differential count heterozygote Male increased eosinophil cell number 5.423667737147753E-9
Fbxo10
Fbxo10tm1b(KOMP)Wtsi
Echo Fractional Shortening homozygote Female decreased cardiac muscle contractility 5.486392673503815E-9
Ppp2r2a
Ppp2r2atm1b(KOMP)Wtsi
Body Composition (DEXA lean/fat) Body length heterozygote Female decreased body length 5.514311229859459E-9
Phf5a
Phf5aem2(IMPC)Marc
Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration heterozygote Female increased fasting circulating glucose level 5.803105995738633E-9
Fbxo15
Fbxo15em1(IMPC)Marc
Hematology White blood cell count homozygote Male increased leukocyte cell number 5.941455771818482E-9
Cyld
Cyldem2(IMPC)Marc
Grip Strength Forelimb and hindlimb grip strength normalised against body weight homozygote Female increased grip strength 5.970625327478274E-9
Zswim1
Zswim1tm1b(KOMP)Mbp
Hematology Lymphocyte cell count homozygote Female increased lymphocyte cell number 6.135889574210296E-9
Fancl
Fancltm1b(EUCOMM)Hmgu
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) homozygote Female decreased bone mineral density 6.624129245125232E-9
Zswim1
Zswim1tm1b(KOMP)Mbp
Hematology Mean corpuscular hemoglobin homozygote Female decreased mean corpuscular hemoglobin 6.746980751870524E-9
Dusp7
Dusp7tm1(KOMP)Wtsi
Clinical Chemistry HDL-cholesterol homozygote Male decreased circulating HDL cholesterol level 7.136004231966808E-9
Fbxo36
Fbxo36tm1b(KOMP)Wtsi
Hematology Mean platelet volume homozygote Female decreased mean platelet volume 7.158761139436365E-9
Hnrnpdl
Hnrnpdlem1(IMPC)Marc
Hematology Eosinophil differential count homozygote Male increased eosinophil cell number 7.204330465526709E-9
Ints6l
Ints6lem1(IMPC)Marc
Echo LVIDs hemizygote dilated heart left ventricle 7.558722536771256E-9
Alg1
Alg1tm1b(KOMP)Wtsi
Hematology Eosinophil cell count heterozygote Female increased eosinophil cell number 7.648031541407363E-9
Esr2
Esr2em1(IMPC)Marc
Body Composition (DEXA lean/fat) Lean mass homozygote Male decreased lean body mass 7.894535691832516E-9
Phf5a
Phf5aem2(IMPC)Marc
Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration heterozygote Male increased fasting circulating glucose level 8.869127654520526E-9
Ash1l
Ash1ltm2b(EUCOMM)Hmgu
Hematology Eosinophil differential count heterozygote Female increased eosinophil cell number 8.980912902245564E-9
Brcc3
Brcc3em1(IMPC)Marc
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 9.913390996985072E-9
Usp45
Usp45em1(IMPC)Marc
Hematology Eosinophil differential count homozygote Male increased eosinophil cell number 9.95139792792088E-9
Ppp2r5e
Ppp2r5eem1(IMPC)Marc
Combined SHIRPA and Dysmorphology Locomotor activity homozygote Male decreased exploration in new environment 1.0062457533877023E-8
Fbxo27
Fbxo27em2(IMPC)Marc
Hematology Basophil cell count homozygote increased basophil cell number 1.0614478185289045E-8
Cyld
Cyldem2(IMPC)Marc
Open Field Periphery distance travelled homozygote Female decreased locomotor activity 1.1384132747593867E-8
Ube2d3
Ube2d3tm1b(EUCOMM)Hmgu
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) heterozygote Male decreased bone mineral content 1.1579621705948284E-8
Ctu2
Ctu2tm1(KOMP)Wtsi
Hematology Eosinophil differential count heterozygote Female increased eosinophil cell number 1.2052303155485333E-8
Bbof1
Bbof1em1(IMPC)Marc
Hematology Mean cell hemoglobin concentration homozygote Female increased mean corpuscular hemoglobin concentration 1.2401885740587204E-8
Usp47
Usp47tm1b(EUCOMM)Wtsi
Clinical Chemistry Alkaline phosphatase homozygote Female increased circulating alkaline phosphatase level 1.2974878060845185E-8
Hectd3
Hectd3tm1(NCOM)Cmhd
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) homozygote Male decreased bone mineral density 1.368046120830968E-8
Cox8a
Cox8aem1(IMPC)Marc
Grip Strength Forelimb grip strength measurement mean homozygote Male decreased grip strength 1.4696404981862088E-8
Ctsm
Ctsmtm1(KOMP)Wtsi
Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration homozygote Female increased fasting circulating glucose level 1.5690677201973813E-8
Usp32
Usp32em1(IMPC)Mhzh
Hematology Mean cell hemoglobin concentration heterozygote Male decreased mean corpuscular hemoglobin concentration 1.615726752390856E-8
Trim37
Trim37em1(IMPC)Marc
Body Composition (DEXA lean/fat) Fat mass homozygote Female increased total body fat amount 1.6499100752298546E-8
Otud3
Otud3em1(IMPC)Marc
Body Composition (DEXA lean/fat) Lean mass homozygote Male increased lean body mass 1.7468568813683305E-8
Ctu2
Ctu2tm1(KOMP)Wtsi
Hematology Eosinophil differential count heterozygote Male increased eosinophil cell number 1.7773221117067806E-8
Atg4a
Atg4aem2(IMPC)Marc
Body Composition (DEXA lean/fat) BMC/Body weight homozygote Male decreased bone mineral content 1.8028059045605005E-8
Ash1l
Ash1ltm2b(EUCOMM)Hmgu
Hematology Eosinophil cell count heterozygote Female increased eosinophil cell number 1.8318846883857987E-8
Ces1f
Ces1ftm1b(KOMP)Wtsi
Hematology Mean cell volume homozygote Male increased mean corpuscular volume 1.839845076290203E-8
Ints6l
Ints6lem1(IMPC)Marc
Echo LVPWd hemizygote thin ventricular wall 1.902434298983735E-8
Zswim1
Zswim1tm1b(KOMP)Mbp
Hematology Monocyte differential count homozygote Male decreased monocyte cell number 1.917098479964352E-8
Ube2z
Ube2zem1(IMPC)Marc
Hematology Eosinophil cell count heterozygote Female increased eosinophil cell number 2.02684002914566E-8
Dlgap2
Dlgap2em1(IMPC)Mhzh
Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration homozygote Female increased fasting circulating glucose level 2.096318496569438E-8
Kics2
Kics2tm1b(KOMP)Wtsi
Clinical Chemistry HDL-cholesterol homozygote Female decreased circulating HDL cholesterol level 2.0969784131352753E-8
Ufm1
Ufm1em1(IMPC)Marc
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) heterozygote Male decreased bone mineral content 2.0979562975753652E-8
Atp13a5
Atp13a5em1(IMPC)Marc
Hematology Eosinophil cell count homozygote Female increased eosinophil cell number 2.1104753500367224E-8
Cpa1
Cpa1em1(IMPC)Marc
Hematology Mean corpuscular hemoglobin homozygote Male increased mean corpuscular hemoglobin 2.1926947368910987E-8
Prpf31
Prpf31tm1a(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Fat/Body weight heterozygote Male increased total body fat amount 2.279264954552218E-8
Usp32
Usp32em1(IMPC)Mhzh
Hematology Mean platelet volume heterozygote Male increased mean platelet volume 2.2882559846948425E-8
Brcc3
Brcc3em1(IMPC)Marc
Hematology Mean cell volume homozygote Male increased mean corpuscular volume 2.6561844279626712E-8
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) BMC/Body weight homozygote Male decreased bone mineral content 2.7975492145060343E-8
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Open Field Number of center entries heterozygote Female decreased locomotor activity 2.897897033449226E-8
Atg4c
Atg4cem2(IMPC)Marc
Hematology Lymphocyte differential count homozygote Male decreased lymphocyte cell number 2.913873586862792E-8
Brcc3
Brcc3em1(IMPC)Marc
Hematology Mean corpuscular hemoglobin homozygote Female increased mean corpuscular hemoglobin 2.9154023195587797E-8
Hnrnpd
Hnrnpdtm1b(KOMP)Wtsi
Hematology Eosinophil differential count heterozygote Male increased eosinophil cell number 3.1510786868693685E-8
Atg4a
Atg4aem2(IMPC)Marc
Body Composition (DEXA lean/fat) Fat/Body weight homozygote Male increased total body fat amount 3.2263510973962184E-8
Otud3
Otud3em1(IMPC)Marc
Open Field Latency to center entry homozygote Male decreased exploration in new environment 3.252362645866924E-8
Fbxo10
Fbxo10tm1b(KOMP)Wtsi
Clinical Chemistry Calcium homozygote Female decreased circulating calcium level 3.2687228923578004E-8
Etaa1
Etaa1em1(IMPC)Marc
Hematology Mean corpuscular hemoglobin homozygote Male decreased mean corpuscular hemoglobin 3.333725118181974E-8
Ces1f
Ces1ftm1b(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Skin color - whole body homozygote Female abnormal skin coloration 3.38484582584897E-8
Esr2
Esr2em1(IMPC)Marc
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) homozygote Male decreased bone mineral content 3.408863591403133E-8
Prickle4
Prickle4em1(IMPC)Marc
Clinical Chemistry Alanine aminotransferase homozygote Female increased circulating alanine transaminase level 3.453489227922546E-8
Ube2h
Ube2htm1b(EUCOMM)Hmgu
Acoustic Startle and Pre-pulse Inhibition (PPI) Response amplitude - S heterozygote Male increased startle reflex 3.5534704068140854E-8
Fbxl18
Fbxl18tm1b(EUCOMM)Hmgu
Hematology Basophil differential count homozygote Female increased basophil cell number 3.652850111279804E-8
Etaa1
Etaa1em1(IMPC)Marc
Hematology Hemoglobin homozygote Male decreased hemoglobin content 4.0568011172581464E-8
Ints6l
Ints6lem1(IMPC)Marc
Echo LVIDd hemizygote dilated heart left ventricle 4.059633340602886E-8
Ints6l
Ints6lem1(IMPC)Marc
Echo LVPWs hemizygote decreased heart left ventricle size 4.42286598456576E-8
Fbxo36
Fbxo36tm1b(KOMP)Wtsi
Hematology Platelet count homozygote Male thrombocytopenia 4.544811105233748E-8
Phf5a
Phf5aem2(IMPC)Marc
Hematology Mean corpuscular hemoglobin heterozygote Female increased mean corpuscular hemoglobin 4.550572541006659E-8
Cyp3a59
Cyp3a59em1(IMPC)Marc
Hematology Platelet count heterozygote Male thrombocytopenia 4.620488525119981E-8
Ppp2r2a
Ppp2r2atm1b(KOMP)Wtsi
Body Composition (DEXA lean/fat) Bone Area heterozygote Female abnormal bone structure 4.940050502000304E-8
Usp16
Usp16tm1b(EUCOMM)Hmgu
Hematology Basophil cell count heterozygote increased basophil cell number 4.980431000944918E-8
Fbxo27
Fbxo27em2(IMPC)Marc
Clinical Chemistry Triglycerides homozygote Male increased circulating triglyceride level 5.1214577467817435E-8
Ccdc83
Ccdc83em1(IMPC)Marc
Hematology White blood cell count homozygote Female decreased leukocyte cell number 5.2914604253828657E-8
Fbxo10
Fbxo10tm1b(KOMP)Wtsi
Echo Ejection Fraction homozygote Female decreased cardiac muscle contractility 5.302877426061059E-8
Ube2e1
Ube2e1em1(IMPC)Marc
Hematology Monocyte differential count homozygote Male increased monocyte cell number 5.418711523930142E-8
Usp32
Usp32em1(IMPC)Mhzh
Clinical Chemistry Glucose heterozygote Male decreased circulating glucose level 5.4728495513245434E-8
Usp40
Usp40em1(IMPC)Marc
Grip Strength Forelimb grip strength measurement mean homozygote Male decreased grip strength 5.5936624221430975E-8
Hnrnpd
Hnrnpdtm1b(KOMP)Wtsi
Hematology Lymphocyte cell count heterozygote Male decreased lymphocyte cell number 5.5939143095429245E-8
Ctu2
Ctu2tm1(KOMP)Wtsi
Hematology Eosinophil cell count heterozygote Male increased eosinophil cell number 5.932002622444088E-8
Ufc1
Ufc1em1(IMPC)Marc
Hematology Eosinophil cell count heterozygote Female increased eosinophil cell number 5.99173120008345E-8
Psmd14
Psmd14tm1b(NCOM)Cmhd
Hematology Basophil differential count heterozygote Male increased basophil cell number 6.211405434441986E-8
Phf5a
Phf5aem2(IMPC)Marc
Body Composition (DEXA lean/fat) Fat/Body weight heterozygote Male decreased total body fat amount 6.230742854995697E-8
Usp15
Usp15em1(IMPC)Marc
Hematology Basophil cell count homozygote Male increased basophil cell number 6.278119712987973E-8
B3galt1
B3galt1em1(IMPC)Marc
Clinical Chemistry Creatinine homozygote Female decreased circulating creatinine level 6.383312012303577E-8
Lypd2
Lypd2em1(IMPC)Marc
Hematology Lymphocyte differential count homozygote Male increased lymphocyte cell number 6.491370641015237E-8
Kics2
Kics2tm1b(KOMP)Wtsi
Clinical Chemistry Phosphorus homozygote Female decreased circulating phosphate level 6.55799681226199E-8
Otud6a
Otud6atm1(KOMP)Vlcg
Open Field Center average speed homozygote Female hyperactivity 6.561285204043088E-8
Prpf31
Prpf31tm1a(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Lean mass heterozygote Male decreased lean body mass 6.764510374068777E-8
Usp31
Usp31em1(IMPC)Marc
Clinical Chemistry Creatinine homozygote Female increased circulating creatinine level 6.85463703575806E-8
Atg4b
Atg4bem1(IMPC)Marc
Clinical Chemistry Alkaline phosphatase homozygote Female increased circulating alkaline phosphatase level 7.075994545857611E-8
Apbb3
Apbb3em1(IMPC)Marc
Hematology Eosinophil differential count homozygote Female increased eosinophil cell number 7.225502685059837E-8
Trim37
Trim37em1(IMPC)Marc
Grip Strength Forelimb grip strength measurement mean homozygote Male increased grip strength 7.611351549030587E-8
Adarb1
Adarb1em1(IMPC)Marc
Hematology Hematocrit heterozygote Male increased hematocrit 7.922461975340411E-8
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Eye Morphology Retinal Blood Vessels Pattern heterozygote Female abnormal retina blood vessel morphology 8.163083009549155E-8
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Eye Morphology Persistence of hyaloid vascular system heterozygote Female persistence of hyaloid vascular system 8.163083009549155E-8
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Eye Morphology Retinal Blood Vessels Structure heterozygote Female abnormal retina blood vessel morphology 8.163083009549155E-8
Gsdma3
Gsdma3tm1(KOMP)Vlcg
Hematology Lymphocyte cell count homozygote Female increased lymphocyte cell number 8.311740629096676E-8
Fbxl8
Fbxl8em2(IMPC)Marc
Hematology Monocyte differential count homozygote Male increased monocyte cell number 8.400895978866174E-8
Fshr
Fshrtm1(KOMP)Vlcg
Body Composition (DEXA lean/fat) Lean/Body weight homozygote Female decreased lean body mass 8.462875911163792E-8
Kdm1a
Kdm1atm1(NCOM)Mfgc
Hematology Eosinophil cell count heterozygote Male increased eosinophil cell number 8.933325545967818E-8
Kdm1a
Kdm1atm1(NCOM)Mfgc
Grip Strength Forelimb and hindlimb grip strength measurement mean heterozygote Male decreased grip strength 9.24734564478058E-8
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Clinical Chemistry Creatinine homozygote Male increased circulating creatinine level 9.642599252401851E-8
Ppp2r2a
Ppp2r2atm1b(KOMP)Wtsi
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) heterozygote Male decreased bone mineral content 9.935833134022687E-8
Trim37
Trim37em1(IMPC)Marc
Hematology Lymphocyte cell count homozygote Male decreased lymphocyte cell number 1.07501456625414E-7
Ppp1r14a
Ppp1r14aem1(IMPC)Marc
Hematology Basophil cell count homozygote increased basophil cell number 1.1342416428306024E-7
Usp16
Usp16tm1b(EUCOMM)Hmgu
Hematology Eosinophil cell count heterozygote Male increased eosinophil cell number 1.1449358794379805E-7
BC049715
BC049715tm1b(KOMP)Mbp
Hematology Red blood cell count homozygote Female decreased erythrocyte cell number 1.1666918453556718E-7
Usp32
Usp32em1(IMPC)Mhzh
Clinical Chemistry Glucose heterozygote Female decreased circulating glucose level 1.170250811810547E-7
Ppp2r2a
Ppp2r2atm1b(KOMP)Wtsi
Body Composition (DEXA lean/fat) Body length heterozygote Male decreased body length 1.17693325307755E-7
Gsdma3
Gsdma3tm1(KOMP)Vlcg
Hematology Red blood cell count homozygote Male decreased erythrocyte cell number 1.198652910261444E-7
Ccdc124
Ccdc124tm1b(KOMP)Wtsi
Open Field Whole arena resting time homozygote Female hyperactivity 1.2153412853876944E-7
Ppp2r2a
Ppp2r2atm1b(KOMP)Wtsi
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) heterozygote Female decreased bone mineral content 1.23036230093021E-7
Atg4c
Atg4cem2(IMPC)Marc
Hematology Neutrophil differential count homozygote Male increased neutrophil cell number 1.2396255044677673E-7
Hectd3
Hectd3tm1(NCOM)Cmhd
Body Composition (DEXA lean/fat) Body length homozygote Female decreased body length 1.244714269432734E-7
Fshr
Fshrtm1(KOMP)Vlcg
Body Composition (DEXA lean/fat) Fat/Body weight homozygote Female increased total body fat amount 1.2537437044102262E-7
Bnip1
Bnip1tm2b(KOMP)Wtsi
Open Field Latency to center entry heterozygote Male decreased exploration in new environment 1.3902877071814146E-7
Phf5a
Phf5aem2(IMPC)Marc
Hematology Mean platelet volume heterozygote Male increased mean platelet volume 1.4092790934228105E-7
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Eye Morphology Retinal Blood Vessels heterozygote Female abnormal retina vasculature morphology 1.6222274723531882E-7
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Eye Morphology Optic Disc heterozygote Female abnormal optic disk morphology 1.6222274723531882E-7
Eddm3b
Eddm3btm1b(KOMP)Wtsi
Hematology Basophil differential count homozygote Male increased basophil cell number 1.635779085518152E-7
Zdhhc2
Zdhhc2tm1b(KOMP)Wtsi
Echo LVIDd homozygote Male dilated heart left ventricle 1.6428371907295514E-7
Zswim1
Zswim1tm1b(KOMP)Mbp
Hematology Red blood cell count homozygote Female increased erythrocyte cell number 1.706667944745277E-7
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Clinical Chemistry Total cholesterol homozygote Male increased circulating cholesterol level 1.7741845681484847E-7
Kdm2b
Kdm2bem1(IMPC)Marc
Hematology Neutrophil cell count heterozygote Male increased neutrophil cell number 1.808108720524615E-7
Ppp1cb
Ppp1cbem2(IMPC)Marc
Open Field Latency to center entry heterozygote Male decreased exploration in new environment 1.8210069185897737E-7
Brcc3
Brcc3em1(IMPC)Marc
Hematology Mean corpuscular hemoglobin homozygote Male increased mean corpuscular hemoglobin 1.826171853736014E-7
Herc6
Herc6tm1b(EUCOMM)Hmgu
Hematology Basophil cell count homozygote Male increased basophil cell number 1.8915805810593156E-7
Bbc3
Bbc3em1(IMPC)Marc
Hematology Mean corpuscular hemoglobin homozygote Male increased mean corpuscular hemoglobin 1.9286390795514308E-7
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Clinical Chemistry Urea (Blood Urea Nitrogen - BUN) heterozygote Male decreased blood urea nitrogen level 1.9567080755678035E-7
Cdc42ep5
Cdc42ep5tm1(KOMP)Wtsi
Hematology Basophil cell count homozygote Male increased basophil cell number 2.007166273187977E-7
Lypd2
Lypd2em1(IMPC)Marc
Hematology Neutrophil cell count homozygote Male decreased neutrophil cell number 2.0486896801230614E-7
Aars2
Aars2tm1(KOMP)Wtsi
Hematology Basophil cell count heterozygote Male increased basophil cell number 2.0546876555727067E-7
Mir203
Mir203tm1(mirKO)Wtsi
Open Field Latency to center entry heterozygote Female decreased exploration in new environment 2.17482295283844E-7
Zfp36
Zfp36tm1(KOMP)Vlcg
Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration heterozygote Male increased fasting circulating glucose level 2.209490190807628E-7
Bola2
Bola2tm1(KOMP)Wtsi
Hematology Mean cell volume homozygote Female decreased mean corpuscular volume 2.2254185694237094E-7
Fbxw13
Fbxw13em2(IMPC)Marc
Hematology Mean corpuscular hemoglobin homozygote Female increased mean corpuscular hemoglobin 2.2457886927895743E-7
Aars2
Aars2tm1(KOMP)Wtsi
Hematology Basophil differential count heterozygote Male increased basophil cell number 2.2560415402494982E-7
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Open Field Whole arena average speed heterozygote Female decreased locomotor activity 2.2993103243607038E-7
Cyp3a59
Cyp3a59em1(IMPC)Marc
Hematology Mean platelet volume heterozygote Female decreased mean platelet volume 2.3427840289969026E-7
Fshr
Fshrtm1(KOMP)Vlcg
Body Composition (DEXA lean/fat) Fat mass homozygote Female increased total body fat amount 2.3717244346244115E-7
Ces2e
Ces2eem1(IMPC)Marc
Clinical Chemistry Creatinine homozygote Female increased circulating creatinine level 2.3928021164465463E-7
Hnrnph1
Hnrnph1tm1b(KOMP)Wtsi
Hematology Lymphocyte cell count heterozygote Female increased lymphocyte cell number 2.602583606403641E-7
Ppp2r5e
Ppp2r5eem1(IMPC)Marc
Hematology Mean cell hemoglobin concentration homozygote Female decreased mean corpuscular hemoglobin concentration 2.6049460188914964E-7
Atp13a5
Atp13a5em1(IMPC)Marc
Grip Strength Forelimb and hindlimb grip strength normalised against body weight homozygote Female increased grip strength 2.6225410465485766E-7
Otud6a
Otud6atm1(KOMP)Vlcg
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 2.7425292614680075E-7
Fbxo10
Fbxo10tm1b(KOMP)Wtsi
Hematology Mean corpuscular hemoglobin homozygote Female decreased mean corpuscular hemoglobin 2.778558041427459E-7
Atg4a
Atg4aem2(IMPC)Marc
Body Composition (DEXA lean/fat) Lean/Body weight homozygote Male decreased lean body mass 2.8449855449252937E-7
Bod1
Bod1tm1b(KOMP)Wtsi
Hematology Basophil cell count heterozygote Female increased basophil cell number 2.8656452855102543E-7
Bend3
Bend3tm1b(KOMP)Mbp
Combined SHIRPA and Dysmorphology Coat - color - head heterozygote Male abnormal coat/hair pigmentation 2.89185891233501E-7
Dusp7
Dusp7tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Coat - color pattern - head homozygote Male abnormal coat/hair pigmentation 2.954453748316155E-7
Ube2d3
Ube2d3tm1b(EUCOMM)Hmgu
Body Composition (DEXA lean/fat) BMC/Body weight heterozygote Male decreased bone mineral content 2.9842510684829904E-7
Atg4a
Atg4aem2(IMPC)Marc
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) homozygote Male decreased bone mineral content 2.9869909212720813E-7
Fbxo24
Fbxo24em2(IMPC)Marc
Hematology Eosinophil differential count homozygote Female increased eosinophil cell number 3.076948473790253E-7
Cdc42ep5
Cdc42ep5tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Coat - color - head homozygote Female abnormal coat/hair pigmentation 3.130067796064395E-7
Bnip1
Bnip1tm2b(KOMP)Wtsi
Hematology Eosinophil differential count heterozygote increased eosinophil cell number 3.1318126048063277E-7
Kics2
Kics2tm1b(KOMP)Wtsi
Clinical Chemistry Urea (Blood Urea Nitrogen - BUN) homozygote Female increased blood urea nitrogen level 3.150096574700001E-7
Fbxo36
Fbxo36tm1b(KOMP)Wtsi
Hematology Monocyte differential count homozygote Male decreased monocyte cell number 3.3992449743891484E-7
Esr2
Esr2em1(IMPC)Marc
Body Composition (DEXA lean/fat) BMC/Body weight homozygote Male decreased bone mineral content 3.6189757679494505E-7
Pfkfb2
Pfkfb2tm1b(KOMP)Wtsi
Echo LVAWs homozygote Male thin ventricular wall 3.694491397254751E-7
Herc6
Herc6tm1b(EUCOMM)Hmgu
Hematology Basophil differential count homozygote Male increased basophil cell number 3.756085504846851E-7
Esr2
Esr2em1(IMPC)Marc
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) homozygote Male decreased bone mineral density 3.784584521326906E-7
Bend3
Bend3tm1b(KOMP)Mbp
Combined SHIRPA and Dysmorphology Coat - color - abdomen heterozygote Male abnormal coat/hair pigmentation 3.785830813285429E-7
Aars2
Aars2tm1(KOMP)Wtsi
Echo LVIDd heterozygote Female abnormal heart left ventricle morphology 3.786310571740614E-7
Ints6l
Ints6lem1(IMPC)Marc
Echo Fractional Shortening hemizygote decreased cardiac muscle contractility 3.9675407492723025E-7
Cdc42ep5
Cdc42ep5tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Coat - color - abdomen homozygote Female abnormal coat/hair pigmentation 4.040675207761524E-7
Phf5a
Phf5aem2(IMPC)Marc
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) heterozygote Male increased bone mineral content 4.1605250089560286E-7
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Open Field Periphery average speed heterozygote Female decreased locomotor activity 4.2798774302355014E-7
Uchl5
Uchl5tm1(NCOM)Mfgc
Open Field Whole arena average speed heterozygote decreased locomotor activity 4.2851752368733287E-7
Fbxo15
Fbxo15em1(IMPC)Marc
Hematology Basophil differential count homozygote Female increased basophil cell number 4.338470489528845E-7
Fbxw8
Fbxw8tm1b(EUCOMM)Hmgu
Hematology Lymphocyte differential count heterozygote Male decreased lymphocyte cell number 4.610863300058554E-7
Cntn3
Cntn3em1(IMPC)Marc
Echo LVPWs homozygote thick ventricular wall 4.6905486783543893E-7
Fbxo36
Fbxo36tm1b(KOMP)Wtsi
Echo LVPWd homozygote Female thick ventricular wall 4.847676677854906E-7
Atg4a
Atg4aem2(IMPC)Marc
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 4.855453425989253E-7
Fbxo38
Fbxo38em2(IMPC)Marc
Body Composition (DEXA lean/fat) Body length homozygote Female decreased body length 5.025020186621987E-7
Trim37
Trim37em1(IMPC)Marc
Hematology White blood cell count homozygote Male decreased leukocyte cell number 5.516156988960574E-7
Phf5a
Phf5aem2(IMPC)Marc
Body Composition (DEXA lean/fat) Lean/Body weight heterozygote Male increased lean body mass 5.550033392864862E-7
Ppp2r5e
Ppp2r5eem1(IMPC)Marc
Hematology Mean platelet volume homozygote Male decreased mean platelet volume 5.578144737228286E-7
Atg4c
Atg4cem2(IMPC)Marc
Hematology Basophil cell count homozygote Male increased basophil cell number 5.797951985186955E-7
Brcc3
Brcc3em1(IMPC)Marc
Hematology Mean platelet volume homozygote Female increased mean platelet volume 5.920801413594745E-7
Cyld
Cyldem2(IMPC)Marc
Open Field Number of center entries homozygote Female decreased locomotor activity 6.053981564946298E-7
Hectd3
Hectd3tm1(NCOM)Cmhd
Grip Strength Forelimb grip strength measurement mean homozygote Male decreased grip strength 6.065786806175311E-7
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) homozygote Male decreased bone mineral content 6.766269962099614E-7
Fbxo15
Fbxo15em1(IMPC)Marc
Hematology Basophil cell count homozygote Male increased basophil cell number 7.118576377251884E-7
Fbxo10
Fbxo10tm1b(KOMP)Wtsi
Clinical Chemistry Urea (Blood Urea Nitrogen - BUN) homozygote Female decreased blood urea nitrogen level 7.481643820028694E-7
Dbil5
Dbil5tm1(KOMP)Wtsi
Clinical Chemistry Alkaline phosphatase homozygote Female increased circulating alkaline phosphatase level 7.570858429062355E-7
Fbxl19
Fbxl19tm1b(EUCOMM)Wtsi
Hematology Basophil cell count heterozygote Male increased basophil cell number 7.58289559144032E-7
Brcc3
Brcc3em1(IMPC)Marc
Hematology Platelet count homozygote Female thrombocytosis 7.707414511060051E-7
Itprid1
Itprid1em1(IMPC)Marc
Hematology Neutrophil cell count homozygote Male increased neutrophil cell number 7.763305234220752E-7
Dtl
Dtltm1b(EUCOMM)Wtsi
Grip Strength Forelimb and hindlimb grip strength measurement mean heterozygote Male decreased grip strength 8.056293836489203E-7
Senp7
Senp7tm1b(EUCOMM)Hmgu
Combined SHIRPA and Dysmorphology Coat - color - head homozygote Female abnormal coat/hair pigmentation 8.126598913804628E-7
Uchl5
Uchl5tm1(NCOM)Mfgc
Open Field Periphery average speed heterozygote decreased locomotor activity 8.213556270675326E-7
Fbxo43
Fbxo43em1(IMPC)Marc
Hematology Red blood cell count homozygote increased erythrocyte cell number 8.298895863845246E-7
Acsm1
Acsm1em1(IMPC)Mhzh
Open Field Latency to center entry homozygote Male decreased exploration in new environment 8.360973993148946E-7
Phf5a
Phf5aem2(IMPC)Marc
Hematology Mean corpuscular hemoglobin heterozygote Male increased mean corpuscular hemoglobin 8.376457572012441E-7
Lsm14a
Lsm14atm1b(KOMP)Wtsi
Hematology Hemoglobin heterozygote Male decreased hemoglobin content 8.428598334830895E-7
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Open Field Center distance travelled heterozygote Female decreased locomotor activity 8.779321660767891E-7
Mir350
Mir350tm1(mirKO)Wtsi
Echo LVIDd homozygote abnormal heart left ventricle morphology 8.785536351751944E-7
Alg1
Alg1tm1b(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Coat - color pattern - back heterozygote Male abnormal coat/hair pigmentation 8.798989483693731E-7
Dusp7
Dusp7tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Coat - color pattern - back homozygote Male abnormal coat/hair pigmentation 8.798989483693731E-7
Atg4a
Atg4aem2(IMPC)Marc
Hematology Eosinophil differential count homozygote Male increased eosinophil cell number 8.904926289687864E-7
Ube2z
Ube2zem1(IMPC)Marc
Hematology Eosinophil cell count heterozygote Male increased eosinophil cell number 9.010527719510719E-7
Ppp2r2a
Ppp2r2atm1b(KOMP)Wtsi
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) heterozygote Male decreased bone mineral density 9.548019761496107E-7
Lsm14a
Lsm14atm1b(KOMP)Wtsi
Hematology Hematocrit heterozygote Male decreased hematocrit 9.755062819749583E-7
Ins1
Ins1em1(IMPC)Marc
Open Field Latency to center entry homozygote Male decreased exploration in new environment 9.842467534326715E-7
Etaa1
Etaa1em1(IMPC)Marc
Hematology Mean platelet volume homozygote Male increased mean platelet volume 9.896072015180835E-7
Phf5a
Phf5aem2(IMPC)Marc
Hematology Red blood cell count heterozygote decreased erythrocyte cell number 9.921664059220348E-7
Kmt2c
Kmt2cem2(IMPC)Marc
Eye Morphology Retina (combined) heterozygote abnormal retina morphology 9.942283440977917E-7
Ppp1r1a
Ppp1r1aem2(IMPC)Marc
Body Composition (DEXA lean/fat) Body length homozygote Male increased body length 1.0187977750319988E-6
Zswim1
Zswim1tm1b(KOMP)Mbp
Hematology Hematocrit homozygote Male decreased hematocrit 1.0401563486084342E-6
Senp7
Senp7tm1b(EUCOMM)Hmgu
Combined SHIRPA and Dysmorphology Coat - color - abdomen homozygote Female abnormal coat/hair pigmentation 1.0477907608219539E-6
Atg4a
Atg4aem2(IMPC)Marc
Body Composition (DEXA lean/fat) Fat mass homozygote Male increased total body fat amount 1.0484210406502825E-6
Hnrnpd
Hnrnpdtm1b(KOMP)Wtsi
Hematology Basophil differential count heterozygote Female increased basophil cell number 1.0664517731129308E-6
Usp15
Usp15em1(IMPC)Marc
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 1.080178208212601E-6
Cpa1
Cpa1em1(IMPC)Marc
Hematology Mean cell volume homozygote Male increased mean corpuscular volume 1.0856920198420994E-6
Pfkfb2
Pfkfb2tm1b(KOMP)Wtsi
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 1.0872247457882622E-6
Fbxo36
Fbxo36tm1b(KOMP)Wtsi
Hematology Monocyte differential count homozygote Female decreased monocyte cell number 1.0956119922411744E-6
Usp30
Usp30em1(IMPC)Marc
Auditory Brain Stem Response Click-evoked ABR threshold homozygote abnormal auditory brainstem response 1.1298487834210391E-6
Senp7
Senp7tm1b(EUCOMM)Hmgu
Acoustic Startle and Pre-pulse Inhibition (PPI) Response amplitude - S homozygote Female increased startle reflex 1.1305482985335402E-6
Itprid1
Itprid1em1(IMPC)Marc
Hematology Lymphocyte differential count homozygote Male decreased lymphocyte cell number 1.1322904356347863E-6
Fbxo43
Fbxo43em1(IMPC)Marc
Hematology Mean platelet volume homozygote Female increased mean platelet volume 1.1345323400746565E-6
Lsm14a
Lsm14atm1b(KOMP)Wtsi
Hematology Red blood cell count heterozygote Male decreased erythrocyte cell number 1.186922190754558E-6
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Intraperitoneal glucose tolerance test (IPGTT) Area under glucose response curve homozygote Male improved glucose tolerance 1.2127381978643825E-6
Fancl
Fancltm1b(EUCOMM)Hmgu
Body Composition (DEXA lean/fat) Fat/Body weight homozygote Female increased total body fat amount 1.212831534758152E-6
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Combined SHIRPA and Dysmorphology Vocalization homozygote Male abnormal vocalization 1.238866275343753E-6
Itprid1
Itprid1em1(IMPC)Marc
Hematology Mean platelet volume homozygote increased mean platelet volume 1.2523955774668138E-6
Ints6l
Ints6lem1(IMPC)Marc
Echo LVAWs hemizygote thin ventricular wall 1.2641114608413773E-6
Lypd2
Lypd2em1(IMPC)Marc
Hematology Monocyte cell count homozygote Male decreased monocyte cell number 1.313927555202099E-6
Trim37
Trim37em1(IMPC)Marc
Body Composition (DEXA lean/fat) Bone Area homozygote Female abnormal bone structure 1.3152117617210024E-6
Kics2
Kics2tm1b(KOMP)Wtsi
Clinical Chemistry Total cholesterol homozygote Female decreased circulating cholesterol level 1.3201232604842517E-6
Ube2z
Ube2zem1(IMPC)Marc
Hematology Basophil differential count heterozygote Female increased basophil cell number 1.3450916185320239E-6
Hectd4
Hectd4em1(IMPC)Marc
Clinical Chemistry Glucose heterozygote Female decreased circulating glucose level 1.350991851722938E-6
Alg1
Alg1tm1b(KOMP)Wtsi
Clinical Chemistry Cholesterol ratio heterozygote Female abnormal cholesterol homeostasis 1.3704883485843311E-6
Ppp2r3a
Ppp2r3atm1(KOMP)Mbp
Clinical Chemistry Alkaline phosphatase homozygote Female increased circulating alkaline phosphatase level 1.390053967043059E-6
Bap1
Bap1em2(IMPC)Marc
Hematology Eosinophil cell count heterozygote Female increased eosinophil cell number 1.3917631349613657E-6
Etaa1
Etaa1em1(IMPC)Marc
Hematology Basophil cell count homozygote Female increased basophil cell number 1.3988760656502564E-6
Prickle4
Prickle4em1(IMPC)Marc
Clinical Chemistry Glucose homozygote Male decreased circulating glucose level 1.419308318872936E-6
Hnrnpd
Hnrnpdtm1b(KOMP)Wtsi
Hematology White blood cell count heterozygote Male decreased leukocyte cell number 1.440633241145406E-6
Cdc42ep5
Cdc42ep5tm1(KOMP)Wtsi
Hematology Basophil differential count homozygote Male increased basophil cell number 1.4779263892705785E-6
Usp31
Usp31em1(IMPC)Marc
Open Field Whole arena resting time homozygote Male decreased locomotor activity 1.4845367104499019E-6
Cdc42ep5
Cdc42ep5tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Coat - color - back homozygote Female abnormal coat/hair pigmentation 1.4857088217468117E-6
Fbxo22
Fbxo22tm1b(EUCOMM)Wtsi
Grip Strength Forelimb and hindlimb grip strength measurement mean homozygote decreased grip strength 1.5057413520480623E-6
Hnrnpr
Hnrnprem1(IMPC)Marc
Hematology Red blood cell distribution width homozygote Male decreased red blood cell distribution width 1.5950035958667286E-6
Ash1l
Ash1ltm2b(EUCOMM)Hmgu
Combined SHIRPA and Dysmorphology Coat - hair texture / appearance - back heterozygote Male abnormal coat appearance 1.6908385305214324E-6
Itprid1
Itprid1em1(IMPC)Marc
Hematology Monocyte cell count homozygote Male increased monocyte cell number 1.7201508626385476E-6
Ccdc83
Ccdc83em1(IMPC)Marc
Echo LVPWd homozygote Male thin ventricular wall 1.7648841321715736E-6
Pfkfb2
Pfkfb2tm1b(KOMP)Wtsi
Echo LVAWs homozygote Female thin ventricular wall 1.8126954728359124E-6
Zfp36
Zfp36tm1(KOMP)Vlcg
Hematology Mean cell volume heterozygote Female decreased mean corpuscular volume 1.8369937606621534E-6
Kdm2b
Kdm2bem1(IMPC)Marc
Clinical Chemistry Albumin heterozygote Male decreased circulating serum albumin level 1.8460766568750842E-6
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Grip Strength Forelimb and hindlimb grip strength normalised against body weight heterozygote Female increased grip strength 1.890629505396646E-6
Kmt2c
Kmt2cem2(IMPC)Marc
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) heterozygote Female increased bone mineral content 1.8981487528435537E-6
Ppp2r3a
Ppp2r3atm1(KOMP)Mbp
Grip Strength Forelimb grip strength measurement mean homozygote Male decreased grip strength 1.9269882614025846E-6
Fbxo38
Fbxo38em2(IMPC)Marc
Hematology Mean platelet volume homozygote Male increased mean platelet volume 1.951347258000169E-6
Esr2
Esr2em1(IMPC)Marc
Hematology Lymphocyte cell count homozygote Female decreased lymphocyte cell number 2.011701553783496E-6
Lsm14a
Lsm14atm1b(KOMP)Wtsi
Hematology Basophil cell count heterozygote Male increased basophil cell number 2.0406882867973763E-6
Fbxw2
Fbxw2tm1b(EUCOMM)Hmgu
Hematology Basophil differential count homozygote Female increased basophil cell number 2.0890176983812125E-6
Kmt2c
Kmt2cem2(IMPC)Marc
Body Composition (DEXA lean/fat) Bone Area heterozygote Female abnormal bone structure 2.111625917677884E-6
Fbxo38
Fbxo38em2(IMPC)Marc
Open Field Periphery distance travelled homozygote Male decreased locomotor activity 2.1428570562420646E-6
Bend3
Bend3tm1b(KOMP)Mbp
Combined SHIRPA and Dysmorphology Coat - color - back heterozygote Male abnormal coat/hair pigmentation 2.1642019873979734E-6
Ppp2r5e
Ppp2r5eem1(IMPC)Marc
Open Field Center average speed homozygote Male decreased locomotor activity 2.2044721390557243E-6
Usp16
Usp16tm1b(EUCOMM)Hmgu
Hematology Basophil differential count heterozygote Male increased basophil cell number 2.2225842712941812E-6
Slco6c1
Slco6c1em1(IMPC)Marc
Clinical Chemistry Phosphorus homozygote Female decreased circulating phosphate level 2.25385042540438E-6
Dusp7
Dusp7tm1(KOMP)Wtsi
Clinical Chemistry Total cholesterol homozygote Male decreased circulating cholesterol level 2.2697861368214944E-6
Fbxw13
Fbxw13em2(IMPC)Marc
Hematology Red blood cell distribution width homozygote decreased red blood cell distribution width 2.278341526107397E-6
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Open Field Number of center entries heterozygote Male decreased locomotor activity 2.323189164599171E-6
Usp31
Usp31em1(IMPC)Marc
Open Field Periphery resting time homozygote Male decreased locomotor activity 2.3349948605755344E-6
Fbxl2
Fbxl2em2(IMPC)Marc
Hematology Red blood cell distribution width homozygote Male decreased red blood cell distribution width 2.3439820324711036E-6
Fbxo22
Fbxo22tm1b(EUCOMM)Wtsi
Echo LVPWd heterozygote thin ventricular wall 2.3733307443762897E-6
Gsdma3
Gsdma3tm1(KOMP)Vlcg
Hematology Hematocrit homozygote Male decreased hematocrit 2.3967813831404783E-6
Arel1
Arel1tm1b(EUCOMM)Hmgu
Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration homozygote Female increased fasting circulating glucose level 2.4530725113436347E-6
Crisp3
Crisp3em1(IMPC)Mhzh
Eye Morphology Retina (combined) homozygote abnormal retina morphology 2.4655632842041086E-6
Hectd4
Hectd4em1(IMPC)Marc
Eye Morphology Retina (combined) heterozygote abnormal retina morphology 2.4655632842041086E-6
Trim37
Trim37em1(IMPC)Marc
Eye Morphology Retina (combined) homozygote abnormal retina morphology 2.4655632842041086E-6
Ube2e1
Ube2e1em1(IMPC)Marc
Eye Morphology Retina (combined) homozygote abnormal retina morphology 2.4655632842041086E-6
Atg4d
Atg4dem1(IMPC)Marc
Eye Morphology Retina (combined) homozygote abnormal retina morphology 2.4655632842041086E-6
Atg4b
Atg4bem1(IMPC)Marc
Eye Morphology Retina (combined) homozygote abnormal retina morphology 2.4655632842041086E-6
Kmt2a
Kmt2aem1(IMPC)Marc
Eye Morphology Retina (combined) heterozygote abnormal retina morphology 2.4655632842041086E-6
Wfdc11
Wfdc11em1(IMPC)Marc
Eye Morphology Retina (combined) homozygote abnormal retina morphology 2.4655632842041086E-6
Pfkfb2
Pfkfb2tm1b(KOMP)Wtsi
Eye Morphology Retina (combined) homozygote abnormal retina morphology 2.4655632842041086E-6
Pfkfb2
Pfkfb2tm1b(KOMP)Wtsi
Hematology Neutrophil differential count homozygote Male decreased neutrophil cell number 2.494431555533083E-6
Fbxl19
Fbxl19tm1b(EUCOMM)Wtsi
Clinical Chemistry Total protein heterozygote Male decreased circulating total protein level 2.4944795313786017E-6
Htr2b
Htr2btm1b(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Fat/Body weight heterozygote increased total body fat amount 2.5483152512606466E-6
Prickle4
Prickle4em1(IMPC)Marc
Open Field Periphery resting time homozygote Female decreased locomotor activity 2.5555764295859262E-6
Ube2z
Ube2zem1(IMPC)Marc
Hematology Basophil differential count heterozygote Male increased basophil cell number 2.567055389590678E-6
Fancl
Fancltm1b(EUCOMM)Hmgu
Combined SHIRPA and Dysmorphology Coat - color - head homozygote abnormal coat/hair pigmentation 2.627422190926154E-6
Fbxo36
Fbxo36tm1b(KOMP)Wtsi
Hematology Basophil differential count homozygote Female increased basophil cell number 2.7303888145979727E-6
Fam166b
Fam166btm1(KOMP)Wtsi
Hematology Eosinophil cell count homozygote increased eosinophil cell number 2.759690460152342E-6
Ints6l
Ints6lem1(IMPC)Marc
Echo Ejection Fraction hemizygote decreased cardiac muscle contractility 2.8151553124189377E-6
Vav2
Vav2em1(IMPC)Marc
Open Field Number of center entries homozygote Female hyperactivity 2.822590204232256E-6
Ufm1
Ufm1em1(IMPC)Marc
Echo Ejection Fraction heterozygote Female decreased cardiac muscle contractility 2.831342271747417E-6
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Hematology Mean platelet volume heterozygote Male increased mean platelet volume 2.8425308755686274E-6
Phf5a
Phf5aem2(IMPC)Marc
Body Composition (DEXA lean/fat) Bone Area heterozygote Female abnormal bone structure 2.853973001037957E-6
Ppp2r3a
Ppp2r3atm1(KOMP)Mbp
Grip Strength Forelimb grip strength measurement mean homozygote Female decreased grip strength 2.8621554974961327E-6
Fbxw8
Fbxw8tm1b(EUCOMM)Hmgu
Hematology Neutrophil differential count heterozygote Male increased neutrophil cell number 2.932275720013422E-6
Kmt2a
Kmt2aem1(IMPC)Marc
Echo HR heterozygote Female increased heart rate 2.9512648325180635E-6
Rabggta
Rabggtatm1.1(KOMP)Vlcg
Hematology Hemoglobin heterozygote Male increased hemoglobin content 2.958835239041946E-6
Ufm1
Ufm1em1(IMPC)Marc
Body Composition (DEXA lean/fat) Lean mass heterozygote Male decreased lean body mass 3.0074086225795327E-6
Acsm1
Acsm1em1(IMPC)Mhzh
Hematology Basophil cell count homozygote increased basophil cell number 3.1252598091668915E-6
Herc4
Herc4tm1b(KOMP)Wtsi
Hematology Basophil cell count homozygote Female increased basophil cell number 3.15673355544277E-6
Prdm2
Prdm2em1(IMPC)Marc
Clinical Chemistry Creatinine homozygote Female increased circulating creatinine level 3.179797658958705E-6
Fbxo36
Fbxo36tm1b(KOMP)Wtsi
Echo LVIDd homozygote Female abnormal heart left ventricle morphology 3.1944125566951698E-6
Erich2
Erich2em1(IMPC)Marc
Hematology Basophil cell count homozygote Female increased basophil cell number 3.2848090540937847E-6
Etaa1
Etaa1em1(IMPC)Marc
Hematology Red blood cell distribution width homozygote Female increased red blood cell distribution width 3.3581000025151297E-6
Ube2w
Ube2wtm1b(EUCOMM)Wtsi
Auditory Brain Stem Response Click-evoked ABR threshold homozygote abnormal auditory brainstem response 3.3635128602327313E-6
Bbc3
Bbc3em1(IMPC)Marc
Open Field Center distance travelled homozygote Male hyperactivity 3.455286105236155E-6
Tmem63a
Tmem63atm1(KOMP)Vlcg
Combined SHIRPA and Dysmorphology Gait homozygote abnormal gait 3.459442268649582E-6
Apbb3
Apbb3em1(IMPC)Marc
Hematology Eosinophil cell count homozygote Female increased eosinophil cell number 3.5145881156495307E-6
Fbxl5
Fbxl5em1(IMPC)Marc
Clinical Chemistry Triglycerides heterozygote Male increased circulating triglyceride level 3.526190539560048E-6
Bap1
Bap1em2(IMPC)Marc
Combined SHIRPA and Dysmorphology Vocalization heterozygote Female abnormal vocalization 3.5507457596395398E-6
Phf5a
Phf5aem2(IMPC)Marc
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) heterozygote Female increased bone mineral content 3.5795919757219963E-6
Fancl
Fancltm1b(EUCOMM)Hmgu
Combined SHIRPA and Dysmorphology Coat - color - abdomen homozygote abnormal coat/hair pigmentation 3.635483153630048E-6
Fbxl19
Fbxl19tm1b(EUCOMM)Wtsi
Clinical Chemistry Glucose heterozygote Male decreased circulating glucose level 3.654288320831256E-6
Ints6l
Ints6lem1(IMPC)Marc
Echo LVAWd hemizygote decreased heart left ventricle size 3.6880196603306103E-6
Fshr
Fshrtm1(KOMP)Vlcg
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) homozygote Female decreased bone mineral content 3.7589304611174157E-6
Atg4a
Atg4aem2(IMPC)Marc
Hematology Basophil cell count homozygote Male increased basophil cell number 3.8094374303909717E-6
Zdhhc2
Zdhhc2tm1b(KOMP)Wtsi
Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration homozygote Male increased fasting circulating glucose level 3.8142691209941404E-6
Senp7
Senp7tm1b(EUCOMM)Hmgu
Combined SHIRPA and Dysmorphology Coat - color - back homozygote Female abnormal coat/hair pigmentation 3.824154646281386E-6
Kdm1a
Kdm1atm1(NCOM)Mfgc
Hematology Mean platelet volume heterozygote Male increased mean platelet volume 3.9592709981661756E-6
Ppp2r2a
Ppp2r2atm1b(KOMP)Wtsi
Body Composition (DEXA lean/fat) BMC/Body weight heterozygote Female decreased bone mineral content 3.9893229768495075E-6
Chst12
Chst12em1(IMPC)Marc
Hematology Lymphocyte cell count homozygote decreased lymphocyte cell number 4.105274001631187E-6
Lypd2
Lypd2em1(IMPC)Marc
Hematology Neutrophil differential count homozygote Male decreased neutrophil cell number 4.134524260734906E-6
Erich2
Erich2em1(IMPC)Marc
Grip Strength Forelimb grip strength measurement mean homozygote Male decreased grip strength 4.144332251598826E-6
Lypd2
Lypd2em1(IMPC)Marc
Hematology Platelet count homozygote Male thrombocytopenia 4.202847776468843E-6
Usp31
Usp31em1(IMPC)Marc
Grip Strength Forelimb grip strength measurement mean homozygote Male decreased grip strength 4.356355930212885E-6
Hnrnpr
Hnrnprem1(IMPC)Marc
Combined SHIRPA and Dysmorphology Locomotor activity homozygote Female decreased exploration in new environment 4.369263024273096E-6
B3galt1
B3galt1em1(IMPC)Marc
Combined SHIRPA and Dysmorphology Activity (body position) homozygote Female abnormal locomotor behavior 4.408454969961895E-6
Nxn
Nxntm1b(EUCOMM)Wtsi
Eye Morphology Optic Disc heterozygote abnormal optic disk morphology 4.450045253179269E-6
Kdm1a
Kdm1atm1(NCOM)Mfgc
Open Field Periphery resting time heterozygote Female decreased locomotor activity 4.4920147956872825E-6
Etaa1
Etaa1em1(IMPC)Marc
Hematology Lymphocyte cell count homozygote increased lymphocyte cell number 4.603292836691253E-6
Ctu2
Ctu2tm1(KOMP)Wtsi
Hematology Basophil differential count heterozygote Female increased basophil cell number 4.674932370107854E-6
Fbxl19
Fbxl19tm1b(EUCOMM)Wtsi
Hematology Eosinophil cell count heterozygote Male increased eosinophil cell number 4.759564490086632E-6
Abhd3
Abhd3em1(IMPC)Marc
Echo LVPWs homozygote Male decreased heart left ventricle size 4.89812737214379E-6
Trim37
Trim37em1(IMPC)Marc
Hematology Basophil differential count homozygote Female increased basophil cell number 4.990130491933087E-6
Fbxo43
Fbxo43em1(IMPC)Marc
Heart Weight Heart weight homozygote Male increased heart weight 5.047370905231219E-6
Ces2e
Ces2eem1(IMPC)Marc
Hematology Red blood cell count homozygote Male decreased erythrocyte cell number 5.048211278335657E-6
Mir203
Mir203tm1(mirKO)Wtsi
Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration heterozygote Male increased fasting circulating glucose level 5.2000746109115425E-6
Fbxo10
Fbxo10tm1b(KOMP)Wtsi
Hematology Hematocrit homozygote Female decreased hematocrit 5.206452897255076E-6
Dagla
Daglatm1a(EUCOMM)Wtsi
Acoustic Startle and Pre-pulse Inhibition (PPI) Response amplitude - S homozygote increased startle reflex 5.265132585918764E-6
Ints6l
Ints6lem1(IMPC)Marc
Clinical Chemistry Triglycerides homozygote increased circulating triglyceride level 5.311852874001488E-6
Ppp2r5e
Ppp2r5eem1(IMPC)Marc
Hematology Hematocrit homozygote Female increased hematocrit 5.3904236665403005E-6
Alg1
Alg1tm1b(KOMP)Wtsi
Hematology Basophil cell count heterozygote Female increased basophil cell number 5.444424914458068E-6
Fbxo28
Fbxo28em1(IMPC)Mhzh
Grip Strength Forelimb grip strength measurement mean heterozygote Female increased grip strength 5.464228706841823E-6
Phf21b
Phf21bem1(IMPC)Marc
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 5.51503899259842E-6
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Body Composition (DEXA lean/fat) Lean/Body weight heterozygote Male increased lean body mass 5.7512229432177264E-6
Usp47
Usp47tm1b(EUCOMM)Wtsi
Clinical Chemistry Glucose homozygote increased circulating glucose level 5.854339178767987E-6
Ufm1
Ufm1em1(IMPC)Marc
Clinical Chemistry Triglycerides heterozygote Male increased circulating triglyceride level 5.939935817877995E-6
Dusp7
Dusp7tm1(KOMP)Wtsi
Clinical Chemistry Cholesterol ratio homozygote abnormal cholesterol homeostasis 5.9817848523380235E-6
Cyp3a59
Cyp3a59em1(IMPC)Marc
Hematology Mean platelet volume heterozygote Male decreased mean platelet volume 6.044693691364955E-6
Ces2e
Ces2eem1(IMPC)Marc
Hematology Platelet count homozygote thrombocytopenia 6.075641067582183E-6
Usp15
Usp15em1(IMPC)Marc
Hematology White blood cell count homozygote Female increased leukocyte cell number 6.135553576314123E-6
Cpa1
Cpa1em1(IMPC)Marc
Hematology Mean cell volume homozygote Female increased mean corpuscular volume 6.17778141531744E-6
Suv39h2
Suv39h2em1(IMPC)Marc
Clinical Chemistry Alkaline phosphatase homozygote Female increased circulating alkaline phosphatase level 6.188343377289129E-6
Blvrb
Blvrbtm1(KOMP)Wtsi
Echo LVAWs homozygote thin ventricular wall 6.2696308305021375E-6
Phf21b
Phf21bem1(IMPC)Marc
Hematology Eosinophil differential count homozygote Male increased eosinophil cell number 6.3450870584347285E-6
Lhcgr
Lhcgrtm1(KOMP)Vlcg
Hematology Platelet count homozygote Male thrombocytopenia 6.480393494712189E-6
Usp26
Usp26em1(IMPC)Marc
Open Field Whole arena average speed hemizygote decreased locomotor activity 6.559599114552839E-6
Usp26
Usp26em1(IMPC)Marc
Open Field Distance travelled - total hemizygote decreased locomotor activity 6.567509444721509E-6
Ints6l
Ints6lem1(IMPC)Marc
Clinical Chemistry Phosphorus homozygote decreased circulating phosphate level 6.801918516430305E-6
Fbxl19
Fbxl19tm1b(EUCOMM)Wtsi
Hematology Neutrophil cell count heterozygote Male increased neutrophil cell number 6.806672899983823E-6
Trim37
Trim37em1(IMPC)Marc
Grip Strength Forelimb grip strength measurement mean homozygote Female increased grip strength 6.811790171923349E-6
Blvrb
Blvrbtm1(KOMP)Wtsi
Auditory Brain Stem Response 30kHz-evoked ABR Threshold homozygote abnormal auditory brainstem response 7.111427294148598E-6
Kdm2b
Kdm2bem1(IMPC)Marc
Hematology Neutrophil differential count heterozygote Male increased neutrophil cell number 7.184144124039449E-6
Fbxw8
Fbxw8tm1b(EUCOMM)Hmgu
Clinical Chemistry Urea (Blood Urea Nitrogen - BUN) heterozygote Male increased blood urea nitrogen level 7.20838852430461E-6
Fbxo28
Fbxo28em1(IMPC)Mhzh
Grip Strength Forelimb grip strength normalised against body weight heterozygote Female increased grip strength 7.300703146029264E-6
Kdm1a
Kdm1atm1(NCOM)Mfgc
Open Field Whole arena resting time heterozygote Female decreased locomotor activity 7.383223874057876E-6
Usp15
Usp15em1(IMPC)Marc
Intraperitoneal glucose tolerance test (IPGTT) Area under glucose response curve homozygote Male improved glucose tolerance 7.384734999504872E-6
Ube2w
Ube2wtm1b(EUCOMM)Wtsi
Grip Strength Forelimb grip strength normalised against body weight homozygote Male increased grip strength 7.610381544509437E-6
Ube2d3
Ube2d3tm1b(EUCOMM)Hmgu
Open Field Periphery resting time heterozygote Male decreased locomotor activity 7.612704393977765E-6
Ppp2r5e
Ppp2r5eem1(IMPC)Marc
Open Field Periphery distance travelled homozygote Female decreased locomotor activity 7.73109513829695E-6
BC049715
BC049715tm1b(KOMP)Mbp
Hematology Hemoglobin homozygote Female decreased hemoglobin content 7.81190101406537E-6
Usp45
Usp45em1(IMPC)Marc
Hematology Mean cell hemoglobin concentration homozygote Female increased mean corpuscular hemoglobin concentration 7.861338417569641E-6
Fbxo10
Fbxo10tm1b(KOMP)Wtsi
Clinical Chemistry Phosphorus homozygote Female decreased circulating phosphate level 7.921938049548771E-6
Lhcgr
Lhcgrtm1(KOMP)Vlcg
Hematology Lymphocyte cell count homozygote increased lymphocyte cell number 7.998222827154677E-6
Hnrnph1
Hnrnph1tm1b(KOMP)Wtsi
Hematology Neutrophil differential count heterozygote Male decreased neutrophil cell number 8.035204700718168E-6
Chst12
Chst12em1(IMPC)Marc
Hematology White blood cell count homozygote decreased leukocyte cell number 8.0445061030332E-6
Slco6c1
Slco6c1em1(IMPC)Marc
Open Field Latency to center entry homozygote decreased exploration in new environment 8.053317287703976E-6
Dusp7
Dusp7tm1(KOMP)Wtsi
Acoustic Startle and Pre-pulse Inhibition (PPI) Response amplitude - S homozygote Male increased startle reflex 8.116619937936775E-6
Fbxo38
Fbxo38em2(IMPC)Marc
Hematology Mean platelet volume homozygote Female increased mean platelet volume 8.140509635268245E-6
Fbxw13
Fbxw13em2(IMPC)Marc
Hematology Mean corpuscular hemoglobin homozygote Male increased mean corpuscular hemoglobin 8.222695214499254E-6
Phf11a
Phf11atm1b(NCOM)Mfgc
Clinical Chemistry Triglycerides heterozygote Male increased circulating triglyceride level 8.244453056249768E-6
Usp31
Usp31em1(IMPC)Marc
Grip Strength Forelimb and hindlimb grip strength measurement mean homozygote Male decreased grip strength 8.281349437311292E-6
Cyld
Cyldem2(IMPC)Marc
Open Field Latency to center entry homozygote Female decreased exploration in new environment 8.317890205944423E-6
Etaa1
Etaa1em1(IMPC)Marc
Hematology Mean cell hemoglobin concentration homozygote Male decreased mean corpuscular hemoglobin concentration 8.385663932131138E-6
Ppp2r5e
Ppp2r5eem1(IMPC)Marc
Open Field Whole arena average speed homozygote decreased locomotor activity 8.397842975682579E-6
Prickle4
Prickle4em1(IMPC)Marc
Open Field Whole arena resting time homozygote Female decreased locomotor activity 8.409304427914321E-6
Fbxl19
Fbxl19tm1b(EUCOMM)Wtsi
Hematology Mean platelet volume heterozygote Male increased mean platelet volume 8.433871698798612E-6
Prmt6
Prmt6em1(IMPC)Marc
Clinical Chemistry Alanine aminotransferase homozygote Male increased circulating alanine transaminase level 8.528615580871701E-6
Ints6l
Ints6lem1(IMPC)Marc
Echo LVAWd homozygote decreased heart left ventricle size 8.581863767176401E-6
Brix1
Brix1tm1b(KOMP)Mbp
Acoustic Startle and Pre-pulse Inhibition (PPI) Response amplitude - S heterozygote Male increased startle reflex 8.592131052864715E-6
Zswim1
Zswim1tm1b(KOMP)Mbp
Hematology Basophil cell count homozygote Male increased basophil cell number 8.720015102881007E-6
Ppp2r5e
Ppp2r5eem1(IMPC)Marc
Hematology Hematocrit homozygote Male increased hematocrit 8.745103514229413E-6
Suv39h2
Suv39h2em1(IMPC)Marc
Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration homozygote Male increased fasting circulating glucose level 9.143344868789427E-6
Fbxo43
Fbxo43em1(IMPC)Marc
Hematology Hematocrit homozygote increased hematocrit 9.235328434442636E-6
Cpa1
Cpa1em1(IMPC)Marc
Hematology White blood cell count homozygote Male increased leukocyte cell number 9.34602849156363E-6
Aars2
Aars2tm1(KOMP)Wtsi
Hematology Red blood cell distribution width heterozygote Male decreased red blood cell distribution width 9.37703407544177E-6
Ankle1
Ankle1tm1(KOMP)Wtsi
Open Field Whole arena resting time homozygote Female decreased locomotor activity 9.570847396389581E-6
Fbxo38
Fbxo38em2(IMPC)Marc
Hematology Basophil cell count homozygote Male increased basophil cell number 9.672585292719305E-6
Slco6c1
Slco6c1em1(IMPC)Marc
Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration homozygote Female increased fasting circulating glucose level 9.682844392955303E-6
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Clinical Chemistry Albumin heterozygote Male decreased circulating serum albumin level 9.747305739438161E-6
Phf3
Phf3em2(IMPC)Marc
Auditory Brain Stem Response 24kHz-evoked ABR Threshold homozygote abnormal auditory brainstem response 9.78074149315944E-6
Usp31
Usp31em1(IMPC)Marc
Clinical Chemistry Phosphorus homozygote Male increased circulating phosphate level 9.833633157541044E-6
Hnrnpd
Hnrnpdtm1b(KOMP)Wtsi
Hematology White blood cell count heterozygote Female decreased leukocyte cell number 9.887345186143648E-6
Gsdmd
Gsdmdem1(IMPC)Marc
Echo LVIDs homozygote dilated heart left ventricle 9.900231816573068E-6
Bola2
Bola2tm1(KOMP)Wtsi
Hematology Hemoglobin homozygote Female decreased hemoglobin content 9.923070138029289E-6
Gsdmd
Gsdmdem1(IMPC)Marc
Echo LVPWs homozygote decreased heart left ventricle size 9.93573121377267E-6
Fancl
Fancltm1b(EUCOMM)Hmgu
Combined SHIRPA and Dysmorphology Coat - color pattern - back homozygote Female abnormal coat/hair pigmentation 9.986470104195178E-6
Fancl
Fancltm1b(EUCOMM)Hmgu
Combined SHIRPA and Dysmorphology Coat - color pattern - head homozygote Female abnormal coat/hair pigmentation 9.986470104195178E-6
Hectd3
Hectd3tm1(NCOM)Cmhd
Grip Strength Forelimb and hindlimb grip strength measurement mean homozygote Female decreased grip strength 1.0010584446717985E-5
Htr2b
Htr2btm1b(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Fat mass heterozygote Male increased total body fat amount 1.0058513908006717E-5
Eddm3b
Eddm3btm1b(KOMP)Wtsi
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 1.0060050954052713E-5
Fancl
Fancltm1b(EUCOMM)Hmgu
Body Composition (DEXA lean/fat) Lean/Body weight homozygote Female decreased lean body mass 1.0193345588049851E-5
Acsm1
Acsm1em1(IMPC)Mhzh
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 1.0251559615426231E-5
Ppp2r2a
Ppp2r2atm1b(KOMP)Wtsi
Body Composition (DEXA lean/fat) Lean mass heterozygote Female decreased lean body mass 1.0306624062650371E-5
Fbxo38
Fbxo38em2(IMPC)Marc
Hematology Lymphocyte cell count homozygote Male increased lymphocyte cell number 1.0381369065726176E-5
Dbil5
Dbil5tm1(KOMP)Wtsi
Clinical Chemistry Total protein homozygote increased circulating total protein level 1.0673926226445474E-5
Fbxo38
Fbxo38em2(IMPC)Marc
Hematology White blood cell count homozygote increased leukocyte cell number 1.0869692232517991E-5
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Eye Morphology Corneal opacity heterozygote Female corneal opacity 1.092221191356657E-5
Itprid1
Itprid1em1(IMPC)Marc
Hematology Neutrophil differential count homozygote Male increased neutrophil cell number 1.12532597995596E-5
Ezh1
Ezh1tm1b(EUCOMM)Wtsi
Hematology Red blood cell count homozygote Female decreased erythrocyte cell number 1.1353967238392215E-5
Phf21b
Phf21bem1(IMPC)Marc
Echo LVAWs homozygote Female thin ventricular wall 1.1522873137437273E-5
Tsg101
Tsg101tm1b(EUCOMM)Hmgu
Open Field Whole arena resting time heterozygote Male decreased locomotor activity 1.1652972716547083E-5
Zswim1
Zswim1tm1b(KOMP)Mbp
Hematology Mean platelet volume homozygote Female increased mean platelet volume 1.1686312063829973E-5
Kdm1a
Kdm1atm1(NCOM)Mfgc
Open Field Whole arena resting time heterozygote Male decreased locomotor activity 1.1910716239071917E-5
Fbxo38
Fbxo38em2(IMPC)Marc
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) homozygote Female decreased bone mineral density 1.192250147141749E-5
Ppp2r5d
Ppp2r5dem2(IMPC)Marc
Combined SHIRPA and Dysmorphology Vocalization homozygote abnormal vocalization 1.1955808076891117E-5
Aars2
Aars2tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Vocalization heterozygote abnormal vocalization 1.1955808076891117E-5
Fbxo38
Fbxo38em2(IMPC)Marc
Hematology Lymphocyte cell count homozygote Female increased lymphocyte cell number 1.2098003935534507E-5
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Clinical Chemistry Urea (Blood Urea Nitrogen - BUN) homozygote Female increased blood urea nitrogen level 1.2098894330847543E-5
Erich2
Erich2em1(IMPC)Marc
Hematology Basophil differential count homozygote Female increased basophil cell number 1.22241444842075E-5
Emc4
Emc4tm1(KOMP)Wtsi
Hematology Eosinophil cell count heterozygote Male increased eosinophil cell number 1.2237772352818865E-5
Fbxl2
Fbxl2em2(IMPC)Marc
Hematology Basophil differential count homozygote Female increased basophil cell number 1.2479657925723586E-5
Trim37
Trim37em1(IMPC)Marc
Hematology Red blood cell distribution width homozygote Female decreased red blood cell distribution width 1.2496116141846869E-5
Atg4a
Atg4aem2(IMPC)Marc
Hematology Basophil differential count homozygote Male increased basophil cell number 1.2560487448354252E-5
Hilpda
Hilpdaem1(IMPC)Mhzh
Echo Ejection Fraction homozygote Female decreased cardiac muscle contractility 1.262663136003539E-5
Ppp2r1b
Ppp2r1btm1b(EUCOMM)Wtsi
Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration homozygote Female increased fasting circulating glucose level 1.2770943612849806E-5
Cpa1
Cpa1em1(IMPC)Marc
Hematology Red blood cell distribution width homozygote Female decreased red blood cell distribution width 1.3135027984390035E-5
Ints6l
Ints6lem1(IMPC)Marc
Hematology Red blood cell distribution width hemizygote decreased red blood cell distribution width 1.330380382569274E-5
Hnrnpd
Hnrnpdtm1b(KOMP)Wtsi
Open Field Center distance travelled heterozygote decreased locomotor activity 1.338689344265731E-5
Kdm2b
Kdm2bem1(IMPC)Marc
Hematology Lymphocyte differential count heterozygote Male decreased lymphocyte cell number 1.3622884580399841E-5
Ces1f
Ces1ftm1b(KOMP)Wtsi
Auditory Brain Stem Response 30kHz-evoked ABR Threshold homozygote abnormal auditory brainstem response 1.3701953321287874E-5
Lsm14a
Lsm14atm1b(KOMP)Wtsi
Auditory Brain Stem Response 30kHz-evoked ABR Threshold heterozygote abnormal auditory brainstem response 1.3701953321287874E-5
Otud6a
Otud6atm1(KOMP)Vlcg
Clinical Chemistry Total cholesterol homozygote increased circulating cholesterol level 1.374715066049248E-5
Fbxo36
Fbxo36tm1b(KOMP)Wtsi
Grip Strength Forelimb and hindlimb grip strength normalised against body weight homozygote Female decreased grip strength 1.3914501323597506E-5
Lypd2
Lypd2em1(IMPC)Marc
Hematology Mean platelet volume homozygote Male decreased mean platelet volume 1.412885103491135E-5
Prickle4
Prickle4em1(IMPC)Marc
Open Field Latency to center entry homozygote Male decreased exploration in new environment 1.416444774804404E-5
Ppp1r14d
Ppp1r14dtm1b(KOMP)Wtsi
Hematology Red blood cell distribution width homozygote Female decreased red blood cell distribution width 1.4236026800062973E-5
Otud6a
Otud6atm1(KOMP)Vlcg
Open Field Periphery distance travelled homozygote Female hyperactivity 1.4246262253436726E-5
Ins1
Ins1em1(IMPC)Marc
Echo LVAWs homozygote thin ventricular wall 1.4416070371225942E-5
Ppp1r14d
Ppp1r14dtm1b(KOMP)Wtsi
Echo LVIDs homozygote Male dilated heart left ventricle 1.4674061276309658E-5
Fbxo2
Fbxo2tm1b(EUCOMM)Wtsi
Open Field Whole arena resting time homozygote Female decreased locomotor activity 1.477940531913191E-5
Atg4b
Atg4bem1(IMPC)Marc
Hematology Basophil differential count homozygote Female increased basophil cell number 1.4790307432122063E-5
Atg4d
Atg4dem1(IMPC)Marc
Echo LVIDs homozygote dilated heart left ventricle 1.5067368622112554E-5
Hectd3
Hectd3tm1(NCOM)Cmhd
Body Composition (DEXA lean/fat) Fat/Body weight homozygote Female increased total body fat amount 1.5248348972818349E-5
Psmd14
Psmd14tm1b(NCOM)Cmhd
Heart Weight Heart weight heterozygote Male increased heart weight 1.543665894132573E-5
Dusp7
Dusp7tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Coat - color - head homozygote Male abnormal coat/hair pigmentation 1.5713178072473966E-5
Ankle1
Ankle1tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Coat - color - head homozygote Male abnormal coat/hair pigmentation 1.5713178072473966E-5
Ppp2r2a
Ppp2r2atm1b(KOMP)Wtsi
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) heterozygote Female decreased bone mineral density 1.580177377036307E-5
Phf21b
Phf21bem1(IMPC)Marc
Hematology Basophil cell count homozygote increased basophil cell number 1.5996651200111955E-5
Usp39
Usp39tm1b(EUCOMM)Hmgu
Combined SHIRPA and Dysmorphology Coat - color - back heterozygote Female abnormal coat/hair pigmentation 1.6036899978644215E-5
Emc4
Emc4tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Coat - color - back heterozygote Female abnormal coat/hair pigmentation 1.6036899978644215E-5
Ankle1
Ankle1tm1(KOMP)Wtsi
Open Field Periphery resting time homozygote Female decreased locomotor activity 1.6113237506942824E-5
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Eye Morphology Pupil Shape heterozygote Female irregularly shaped pupil 1.6151851014001295E-5
Vav2
Vav2em1(IMPC)Marc
Echo LVPWd homozygote thin ventricular wall 1.6176383724086918E-5
Ctsm
Ctsmtm1(KOMP)Wtsi
Hematology Monocyte cell count homozygote Male increased monocyte cell number 1.634360341995489E-5
Ppp2r5e
Ppp2r5eem1(IMPC)Marc
Combined SHIRPA and Dysmorphology Activity (body position) homozygote Male abnormal locomotor behavior 1.6887257515918463E-5
Usp50
Usp50tm1(KOMP)Vlcg
Eye Morphology Pupil Shape heterozygote Male irregularly shaped pupil 1.701610381132923E-5
Otud6a
Otud6atm1(KOMP)Vlcg
Clinical Chemistry HDL-cholesterol homozygote increased circulating HDL cholesterol level 1.7451453459216282E-5
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Hematology Neutrophil cell count heterozygote Male increased neutrophil cell number 1.749792863847688E-5
Bap1
Bap1em2(IMPC)Marc
Body Composition (DEXA lean/fat) Bone Area heterozygote abnormal bone structure 1.7514628780190833E-5
Ces2e
Ces2eem1(IMPC)Marc
Hematology Hematocrit homozygote Female decreased hematocrit 1.7564401787240058E-5
Bbof1
Bbof1em1(IMPC)Marc
Hematology Basophil cell count homozygote increased basophil cell number 1.7572765500517562E-5
Ube2d3
Ube2d3tm1b(EUCOMM)Hmgu
Open Field Whole arena resting time heterozygote Male decreased locomotor activity 1.7584939996595494E-5
Kdm1a
Kdm1atm1(NCOM)Mfgc
Open Field Periphery average speed heterozygote decreased locomotor activity 1.7686326827970333E-5
Fbxl2
Fbxl2em2(IMPC)Marc
Hematology Hematocrit homozygote Male increased hematocrit 1.8007423932431266E-5
Fancl
Fancltm1b(EUCOMM)Hmgu
Body Composition (DEXA lean/fat) Lean mass homozygote Female decreased lean body mass 1.80368879227899E-5
Ints6l
Ints6lem1(IMPC)Marc
Open Field Latency to center entry hemizygote decreased exploration in new environment 1.804816201911308E-5
Ctu2
Ctu2tm1(KOMP)Wtsi
Hematology Basophil cell count heterozygote Male increased basophil cell number 1.8269442080054432E-5
Fbxl15
Fbxl15em1(IMPC)Marc
Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration homozygote increased fasting circulating glucose level 1.8316854038857855E-5
Lmo7
Lmo7em1(IMPC)Marc
Clinical Chemistry Creatinine homozygote Female increased circulating creatinine level 1.850862281571608E-5
Esr2
Esr2em1(IMPC)Marc
Echo LVPWd homozygote Female thin ventricular wall 1.8653272491064854E-5
Aars2
Aars2tm1(KOMP)Wtsi
Hematology Neutrophil cell count heterozygote increased neutrophil cell number 1.8738792277872562E-5
Uchl5
Uchl5tm1(NCOM)Mfgc
Open Field Periphery distance travelled heterozygote decreased locomotor activity 1.8741713574854657E-5
Htr4
Htr4em2(IMPC)Marc
Hematology Mean cell volume homozygote increased mean corpuscular volume 1.9005019566975534E-5
Kdm2b
Kdm2bem1(IMPC)Marc
Echo LVAWd heterozygote decreased heart left ventricle size 1.9308001355966553E-5
Ces2f
Ces2ftm1b(KOMP)Wtsi
Hematology Platelet count homozygote Male thrombocytosis 1.935009640874341E-5
Fbxo36
Fbxo36tm1b(KOMP)Wtsi
Hematology Neutrophil differential count homozygote Female increased neutrophil cell number 1.9366565538803115E-5
Dusp7
Dusp7tm1(KOMP)Wtsi
Echo LVIDd homozygote Male dilated heart left ventricle 1.947710188687779E-5
Trim37
Trim37em1(IMPC)Marc
Echo LVPWs homozygote decreased heart left ventricle size 1.9553090169210918E-5
Dusp7
Dusp7tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Coat - color - abdomen homozygote Male abnormal coat/hair pigmentation 1.9569177311495878E-5
Alg1
Alg1tm1b(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Coat - color - abdomen heterozygote Male abnormal coat/hair pigmentation 1.9569177311495878E-5
Ankle1
Ankle1tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Coat - color - abdomen homozygote Male abnormal coat/hair pigmentation 1.9569177311495878E-5
Fbxo22
Fbxo22tm1b(EUCOMM)Wtsi
Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI2 homozygote decreased prepulse inhibition 1.9631779650808312E-5
Prxl2a
Prxl2aem1(IMPC)Marc
Echo LVPWd homozygote thin ventricular wall 1.9652214177767746E-5
Fbxo36
Fbxo36tm1b(KOMP)Wtsi
Hematology Red blood cell distribution width homozygote Female increased red blood cell distribution width 1.967729622265324E-5
Hilpda
Hilpdaem1(IMPC)Mhzh
Echo LVPWd homozygote Male thin ventricular wall 1.9962362785008736E-5
Snx25
Snx25tm1b(KOMP)Wtsi
Echo LVIDs heterozygote Male dilated heart left ventricle 2.0057168512721546E-5
Rbm11
Rbm11em1(IMPC)Marc
Echo LVPWd homozygote Male thin ventricular wall 2.0121649868087843E-5
Abhd3
Abhd3em1(IMPC)Marc
Open Field Latency to center entry homozygote Male decreased exploration in new environment 2.0245652194716968E-5
Ins1
Ins1em1(IMPC)Marc
Grip Strength Forelimb and hindlimb grip strength measurement mean homozygote Male decreased grip strength 2.059483631455805E-5
Atg4c
Atg4cem2(IMPC)Marc
Hematology Basophil differential count homozygote Male increased basophil cell number 2.0628664060495794E-5
Fbxo24
Fbxo24em2(IMPC)Marc
Hematology Eosinophil cell count homozygote increased eosinophil cell number 2.0705761926365085E-5
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Open Field Percentage center movement time heterozygote Female increased anxiety-related response 2.0732288248836994E-5
Ppp1cc
Ppp1cctm1b(EUCOMM)Wtsi
Open Field Periphery resting time homozygote Female decreased locomotor activity 2.1171306798350997E-5
Hnrnpr
Hnrnprem1(IMPC)Marc
Hematology Basophil cell count homozygote Male increased basophil cell number 2.1191608539083973E-5
Kmt2a
Kmt2aem1(IMPC)Marc
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) heterozygote Female decreased bone mineral density 2.131239671143703E-5
Fbxl2
Fbxl2em2(IMPC)Marc
Hematology Hemoglobin homozygote Female increased hemoglobin content 2.13465464184992E-5
Acsm1
Acsm1em1(IMPC)Mhzh
Open Field Latency to center entry homozygote Female decreased exploration in new environment 2.138186027877964E-5
Esr2
Esr2em1(IMPC)Marc
Hematology White blood cell count homozygote Female decreased leukocyte cell number 2.140650940418709E-5
Cntn3
Cntn3em1(IMPC)Marc
Clinical Chemistry Urea (Blood Urea Nitrogen - BUN) homozygote Male increased blood urea nitrogen level 2.1442405341076665E-5
Ube2z
Ube2zem1(IMPC)Marc
Echo LVAWd heterozygote decreased heart left ventricle size 2.180420960939955E-5
Ufm1
Ufm1em1(IMPC)Marc
Hematology Red blood cell distribution width heterozygote Male decreased red blood cell distribution width 2.207359102612827E-5
Acsm1
Acsm1em1(IMPC)Mhzh
Echo LVAWs homozygote thin ventricular wall 2.2139534848975018E-5
Ube2e1
Ube2e1em1(IMPC)Marc
Hematology Mean platelet volume homozygote Male increased mean platelet volume 2.2274551156442612E-5
B3galt1
B3galt1em1(IMPC)Marc
Open Field Number of center entries homozygote decreased locomotor activity 2.2338717826642096E-5
Cnpy1
Cnpy1tm1(KOMP)Wtsi
Clinical Chemistry Albumin homozygote Male decreased circulating serum albumin level 2.2363565221894532E-5
Fshr
Fshrtm1(KOMP)Vlcg
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) homozygote Female decreased bone mineral density 2.3048176444717683E-5
Fancl
Fancltm1b(EUCOMM)Hmgu
Combined SHIRPA and Dysmorphology Coat - color - back homozygote abnormal coat/hair pigmentation 2.3157106625149027E-5
Prmt6
Prmt6em1(IMPC)Marc
Echo LVAWd homozygote decreased heart left ventricle size 2.3283546397578903E-5
Ube2w
Ube2wtm1b(EUCOMM)Wtsi
Grip Strength Forelimb grip strength normalised against body weight homozygote Female increased grip strength 2.390448389633093E-5
Abhd3
Abhd3em1(IMPC)Marc
Echo Ejection Fraction homozygote decreased cardiac muscle contractility 2.402983227511868E-5
Fbxo2
Fbxo2tm1b(EUCOMM)Wtsi
Acoustic Startle and Pre-pulse Inhibition (PPI) Response amplitude - S homozygote decreased startle reflex 2.4071880034171045E-5
Hnrnpd
Hnrnpdtm1b(KOMP)Wtsi
Hematology Basophil cell count heterozygote Female increased basophil cell number 2.4164952264982276E-5
Bola2
Bola2tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Coat - color - head homozygote abnormal coat/hair pigmentation 2.4177479645004496E-5
Ube2d3
Ube2d3tm1b(EUCOMM)Hmgu
Body Composition (DEXA lean/fat) Lean/Body weight heterozygote Male decreased lean body mass 2.4268687411677092E-5
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Eye Morphology Pupil Light Response heterozygote Female impaired pupillary reflex 2.462906195432879E-5
Usp46
Usp46em1(IMPC)Marc
Clinical Chemistry Triglycerides homozygote Male increased circulating triglyceride level 2.4725593902985565E-5
Bod1
Bod1tm1b(KOMP)Wtsi
Heart Weight Heart weight heterozygote Male increased heart weight 2.4974906409624964E-5
Usp46
Usp46em1(IMPC)Marc
Clinical Chemistry Total cholesterol homozygote Female increased circulating cholesterol level 2.52102327067405E-5
Trim37
Trim37em1(IMPC)Marc
Echo LVPWd homozygote thin ventricular wall 2.526803655200638E-5
Suv39h2
Suv39h2em1(IMPC)Marc
Grip Strength Forelimb and hindlimb grip strength normalised against body weight homozygote Female increased grip strength 2.5350676878588274E-5
Uchl5
Uchl5tm1(NCOM)Mfgc
Open Field Periphery resting time heterozygote Male decreased locomotor activity 2.5356879632454365E-5
Kdm1a
Kdm1atm1(NCOM)Mfgc
Open Field Whole arena average speed heterozygote decreased locomotor activity 2.558185406087432E-5
Ufm1
Ufm1em1(IMPC)Marc
Echo LVIDs heterozygote Female dilated heart left ventricle 2.5583394744899124E-5
Blvrb
Blvrbtm1(KOMP)Wtsi
Auditory Brain Stem Response 24kHz-evoked ABR Threshold homozygote abnormal auditory brainstem response 2.5789206119952723E-5
Zswim1
Zswim1tm1b(KOMP)Mbp
Body Composition (DEXA lean/fat) Lean/Body weight homozygote Male increased lean body mass 2.6291238100384362E-5
Kdm1a
Kdm1atm1(NCOM)Mfgc
Grip Strength Forelimb and hindlimb grip strength measurement mean heterozygote Female decreased grip strength 2.6301057005184703E-5
Ces2e
Ces2eem1(IMPC)Marc
Hematology Hemoglobin homozygote Male decreased hemoglobin content 2.6855261239688843E-5
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Combined SHIRPA and Dysmorphology Locomotor activity heterozygote Female decreased exploration in new environment 2.700801269384101E-5
Fancl
Fancltm1b(EUCOMM)Hmgu
Body Composition (DEXA lean/fat) Body length homozygote Female decreased body length 2.7030213459511288E-5
Sorcs2
Sorcs2em1(IMPC)Marc
Open Field Center resting time homozygote Female decreased locomotor activity 2.7037158361054026E-5
Atg4c
Atg4cem2(IMPC)Marc
Heart Weight Heart weight homozygote Male increased heart weight 2.7385945941205136E-5
Hnrnph1
Hnrnph1tm1b(KOMP)Wtsi
Hematology Mean platelet volume heterozygote Female increased mean platelet volume 2.7426471206126735E-5
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Clinical Chemistry HDL-cholesterol homozygote increased circulating HDL cholesterol level 2.765271347016096E-5
Usp45
Usp45em1(IMPC)Marc
Hematology Monocyte cell count homozygote Male increased monocyte cell number 2.78704465017654E-5
Dagla
Daglatm1a(EUCOMM)Wtsi
Open Field Periphery permanence time homozygote decreased thigmotaxis 2.7998767109238543E-5
Hnrnpd
Hnrnpdtm1b(KOMP)Wtsi
Hematology Eosinophil cell count heterozygote Male increased eosinophil cell number 2.8702776035061106E-5
Fbxo10
Fbxo10tm1b(KOMP)Wtsi
Hematology Neutrophil differential count homozygote Female decreased neutrophil cell number 2.8924339858349413E-5
Dagla
Daglatm1a(EUCOMM)Wtsi
Open Field Center permanence time homozygote decreased thigmotaxis 2.894242606998887E-5
Dagla
Daglatm1a(EUCOMM)Wtsi
Open Field Percentage center time homozygote abnormal behavior 2.8972111977054738E-5
Fshr
Fshrtm1(KOMP)Vlcg
Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration homozygote Female increased fasting circulating glucose level 2.8973669031984173E-5
Carm1
Carm1tm1b(EUCOMM)Hmgu
Hematology Lymphocyte cell count heterozygote decreased lymphocyte cell number 2.9056529456283897E-5
Kmt2a
Kmt2aem1(IMPC)Marc
Body Composition (DEXA lean/fat) Lean/Body weight heterozygote Male increased lean body mass 2.925129228970036E-5
Esr2
Esr2em1(IMPC)Marc
Clinical Chemistry Albumin homozygote increased circulating serum albumin level 2.985830360557884E-5
Phf5a
Phf5aem2(IMPC)Marc
Body Composition (DEXA lean/fat) Fat/Body weight heterozygote Female decreased total body fat amount 3.015388938365504E-5
Mir204
Mir204tm1(mirKO)Wtsi
Eye Morphology Lens Opacity homozygote cataract 3.0354507543961518E-5
Ppp2r5e
Ppp2r5eem1(IMPC)Marc
Open Field Periphery average speed homozygote decreased locomotor activity 3.042813295905944E-5
Fbxo27
Fbxo27em2(IMPC)Marc
Hematology Basophil differential count homozygote Male increased basophil cell number 3.060934250243008E-5
Vav2
Vav2em1(IMPC)Marc
Echo LVAWd homozygote decreased heart left ventricle size 3.066917270189151E-5
Fbxo38
Fbxo38em2(IMPC)Marc
Echo HR homozygote Female increased heart rate 3.083041883655824E-5
Fam166b
Fam166btm1(KOMP)Wtsi
Clinical Chemistry Urea (Blood Urea Nitrogen - BUN) homozygote increased blood urea nitrogen level 3.087299410253763E-5
Phf21b
Phf21bem1(IMPC)Marc
Echo LVAWd homozygote Female decreased heart left ventricle size 3.093278064625338E-5
Atg4b
Atg4bem1(IMPC)Marc
Clinical Chemistry Total protein homozygote Female decreased circulating total protein level 3.104930874542333E-5
Bola2
Bola2tm1(KOMP)Wtsi
Clinical Chemistry Iron homozygote decreased circulating iron level 3.106024814769626E-5
Tmigd1
Tmigd1em1(IMPC)Marc
Clinical Chemistry Urea (Blood Urea Nitrogen - BUN) homozygote increased blood urea nitrogen level 3.111377009190619E-5
Cox8a
Cox8aem1(IMPC)Marc
Open Field Center distance travelled homozygote decreased locomotor activity 3.127333548036404E-5
Hnrnpr
Hnrnprem1(IMPC)Marc
Hematology Eosinophil cell count homozygote Female increased eosinophil cell number 3.128179014311172E-5
Htr2b
Htr2btm1b(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Lean/Body weight heterozygote decreased lean body mass 3.133670907118358E-5
Emc4
Emc4tm1(KOMP)Wtsi
Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration heterozygote Female increased fasting circulating glucose level 3.178541737725027E-5
Bola2
Bola2tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Coat - color - abdomen homozygote abnormal coat/hair pigmentation 3.179077248205431E-5
Ezh1
Ezh1tm1b(EUCOMM)Wtsi
Hematology Hematocrit homozygote Female decreased hematocrit 3.1949279218679294E-5
Ppp1r14a
Ppp1r14aem1(IMPC)Marc
Hematology Monocyte cell count homozygote Male increased monocyte cell number 3.233133247704245E-5
Atp13a5
Atp13a5em1(IMPC)Marc
Grip Strength Forelimb and hindlimb grip strength measurement mean homozygote Female increased grip strength 3.286396895418875E-5
Phf5a
Phf5aem2(IMPC)Marc
Hematology Red blood cell distribution width heterozygote Male increased red blood cell distribution width 3.3102660381700844E-5
Fbxl19
Fbxl19tm1b(EUCOMM)Wtsi
Hematology White blood cell count heterozygote Male increased leukocyte cell number 3.323330747662112E-5
Ints6l
Ints6lem1(IMPC)Marc
Hematology Red blood cell distribution width homozygote decreased red blood cell distribution width 3.351651321281679E-5
Usp16
Usp16tm1b(EUCOMM)Hmgu
Hematology Eosinophil differential count heterozygote Male increased eosinophil cell number 3.403360824449919E-5
Alg1
Alg1tm1b(KOMP)Wtsi
Hematology Lymphocyte cell count heterozygote Female increased lymphocyte cell number 3.414096136111766E-5
Suv39h2
Suv39h2em1(IMPC)Marc
Hematology Mean cell hemoglobin concentration homozygote decreased mean corpuscular hemoglobin concentration 3.441489388933405E-5
Usp26
Usp26em1(IMPC)Marc
Clinical Chemistry Triglycerides homozygote increased circulating triglyceride level 3.485351408016868E-5
Cntn3
Cntn3em1(IMPC)Marc
Clinical Chemistry Triglycerides homozygote Male increased circulating triglyceride level 3.5147932067047805E-5
Ppp2r5e
Ppp2r5eem1(IMPC)Marc
Body Composition (DEXA lean/fat) Bone Area homozygote Female abnormal bone structure 3.532788105076179E-5
Chst12
Chst12em1(IMPC)Marc
Acoustic Startle and Pre-pulse Inhibition (PPI) Response amplitude - S homozygote Male increased startle reflex 3.597177055780776E-5
Fbxo2
Fbxo2tm1b(EUCOMM)Wtsi
Clinical Chemistry Glucose homozygote Male increased circulating glucose level 3.637306144810282E-5
Kdm2b
Kdm2bem1(IMPC)Marc
Clinical Chemistry Phosphorus heterozygote Male decreased circulating phosphate level 3.686350828502327E-5
Arel1
Arel1tm1b(EUCOMM)Hmgu
Open Field Periphery average speed homozygote Female hyperactivity 3.745317007997073E-5
Trim37
Trim37em1(IMPC)Marc
Hematology Mean platelet volume homozygote decreased mean platelet volume 3.800898412009701E-5
B3galt1
B3galt1em1(IMPC)Marc
Open Field Periphery resting time homozygote Male decreased locomotor activity 3.8018511986592785E-5
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Eye Morphology Iris/Pupil heterozygote Female abnormal iris morphology 3.804771404247731E-5
Cyld
Cyldem2(IMPC)Marc
Open Field Center distance travelled homozygote Female decreased locomotor activity 3.827538603218272E-5
Fbxl18
Fbxl18tm1b(EUCOMM)Hmgu
Hematology Eosinophil cell count homozygote Female increased eosinophil cell number 3.840684803435579E-5
Fbxo36
Fbxo36tm1b(KOMP)Wtsi
Hematology Monocyte cell count homozygote decreased monocyte cell number 3.845714309136383E-5
Ube2d3
Ube2d3tm1b(EUCOMM)Hmgu
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) heterozygote Male decreased bone mineral density 3.846599065582268E-5
Ppp1r14a
Ppp1r14aem1(IMPC)Marc
Hematology Lymphocyte cell count homozygote Male increased lymphocyte cell number 3.846761319437064E-5
Hnrnph1
Hnrnph1tm1b(KOMP)Wtsi
Hematology Lymphocyte differential count heterozygote Male increased lymphocyte cell number 3.8876827602507547E-5
Fbxo36
Fbxo36tm1b(KOMP)Wtsi
Hematology Platelet count homozygote Female thrombocytopenia 3.9332997403107584E-5
Prmt6
Prmt6em1(IMPC)Marc
Clinical Chemistry Creatinine homozygote increased circulating creatinine level 3.937279689125717E-5
Usp26
Usp26em1(IMPC)Marc
Hematology Basophil cell count homozygote increased basophil cell number 3.982709677075036E-5
Phf11a
Phf11atm1b(NCOM)Mfgc
Hematology Basophil cell count heterozygote increased basophil cell number 3.9831942558521405E-5
Dlgap2
Dlgap2em1(IMPC)Mhzh
Open Field Distance travelled - total homozygote decreased locomotor activity 4.002971400041133E-5
Chchd5
Chchd5em1(IMPC)Marc
Body Composition (DEXA lean/fat) Lean mass heterozygote Male increased lean body mass 4.0058166632661596E-5
Ppp2r5e
Ppp2r5eem1(IMPC)Marc
Body Composition (DEXA lean/fat) BMC/Body weight homozygote Female decreased bone mineral content 4.010664270026609E-5
Herc4
Herc4tm1b(KOMP)Wtsi
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 4.019907282781787E-5
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Clinical Chemistry Creatinine heterozygote Male decreased circulating creatinine level 4.091069058631547E-5
Htr4
Htr4em2(IMPC)Marc
Eye Morphology Pupil Light Response homozygote Male impaired pupillary reflex 4.09969907195773E-5
Ppp1r14a
Ppp1r14aem1(IMPC)Marc
Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration homozygote Male increased fasting circulating glucose level 4.103274113731459E-5
Hectd4
Hectd4em1(IMPC)Marc
Clinical Chemistry Alanine aminotransferase heterozygote Female increased circulating alanine transaminase level 4.104883555555716E-5
Fbxl18
Fbxl18tm1b(EUCOMM)Hmgu
Eye Morphology Cornea homozygote abnormal cornea morphology 4.193471613689326E-5
Bola2
Bola2tm1(KOMP)Wtsi
Intraperitoneal glucose tolerance test (IPGTT) Initial response to glucose challenge homozygote Female improved glucose tolerance 4.2634135752450675E-5
Blvrb
Blvrbtm1(KOMP)Wtsi
Clinical Chemistry Creatinine homozygote Female increased circulating creatinine level 4.3148931581526995E-5
Usp45
Usp45em1(IMPC)Marc
Hematology Mean corpuscular hemoglobin homozygote increased mean corpuscular hemoglobin 4.327127680880949E-5
Atg4d
Atg4dem1(IMPC)Marc
Open Field Percentage center movement time homozygote Female increased anxiety-related response 4.399787212605588E-5
Bbc3
Bbc3em1(IMPC)Marc
Open Field Whole arena average speed homozygote Female hyperactivity 4.407595406519249E-5
Usp16
Usp16tm1b(EUCOMM)Hmgu
Hematology Mean platelet volume heterozygote decreased mean platelet volume 4.427748717716895E-5
Hnrnpd
Hnrnpdtm1b(KOMP)Wtsi
Open Field Percentage center time heterozygote Female abnormal behavior 4.475734749576077E-5
Hnrnpd
Hnrnpdtm1b(KOMP)Wtsi
Open Field Center permanence time heterozygote Female increased thigmotaxis 4.4762480683857575E-5
Alg1
Alg1tm1b(KOMP)Wtsi
Hematology Basophil differential count heterozygote Female increased basophil cell number 4.4972617615712807E-5
Hnrnpd
Hnrnpdtm1b(KOMP)Wtsi
Open Field Periphery permanence time heterozygote Female increased thigmotaxis 4.498858834267594E-5
Cox8a
Cox8aem1(IMPC)Marc
Clinical Chemistry Phosphorus homozygote Male decreased circulating phosphate level 4.504831667873077E-5
Ash1l
Ash1ltm2b(EUCOMM)Hmgu
Grip Strength Forelimb grip strength normalised against body weight heterozygote increased grip strength 4.510891085374169E-5
Hnrnpm
Hnrnpmem1(IMPC)Marc
Echo HR heterozygote increased heart rate 4.53756692877505E-5
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Open Field Periphery average speed homozygote Female decreased locomotor activity 4.564999107969925E-5
Vav2
Vav2em1(IMPC)Marc
Open Field Center distance travelled homozygote Male hyperactivity 4.594353595166467E-5
BC049715
BC049715tm1b(KOMP)Mbp
Hematology Hematocrit homozygote Female decreased hematocrit 4.706866093329154E-5
Speg
Spegtm1b(KOMP)Wtsi
Hematology Basophil differential count heterozygote Male increased basophil cell number 4.7114575863815844E-5
Prmt6
Prmt6em1(IMPC)Marc
Clinical Chemistry Aspartate aminotransferase homozygote Male increased circulating aspartate transaminase level 4.72136125608813E-5
Usp31
Usp31em1(IMPC)Marc
Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI2 homozygote Male increased prepulse inhibition 4.724495011032559E-5
Pfkfb2
Pfkfb2tm1b(KOMP)Wtsi
Hematology Lymphocyte differential count homozygote Male increased lymphocyte cell number 4.727742270915769E-5
Bbc3
Bbc3em1(IMPC)Marc
Open Field Number of center entries homozygote Male hyperactivity 4.7288798668887466E-5
Usp32
Usp32em1(IMPC)Mhzh
Hematology Neutrophil differential count heterozygote decreased neutrophil cell number 4.806851939065382E-5
Fbxo38
Fbxo38em2(IMPC)Marc
Clinical Chemistry Alanine aminotransferase homozygote increased circulating alanine transaminase level 4.8221398174064234E-5
Apbb3
Apbb3em1(IMPC)Marc
Body Composition (DEXA lean/fat) Lean/Body weight homozygote Female increased lean body mass 4.82648829347454E-5
Ppp2r5e
Ppp2r5eem1(IMPC)Marc
Auditory Brain Stem Response 30kHz-evoked ABR Threshold homozygote abnormal auditory brainstem response 4.977999196853489E-5
Dbil5
Dbil5tm1(KOMP)Wtsi
Clinical Chemistry Glucose homozygote Male increased circulating glucose level 4.978841752745211E-5
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Heart Weight Heart weight homozygote Female decreased heart weight 4.98083682032302E-5
Herc4
Herc4tm1b(KOMP)Wtsi
Hematology Eosinophil differential count homozygote Male increased eosinophil cell number 4.9907237553270534E-5
Otud3
Otud3em1(IMPC)Marc
Hematology Monocyte differential count homozygote Male increased monocyte cell number 5.0055507017532364E-5
Ufm1
Ufm1em1(IMPC)Marc
Clinical Chemistry Total protein heterozygote decreased circulating total protein level 5.041808253736235E-5
Dlgap2
Dlgap2em1(IMPC)Mhzh
Open Field Whole arena average speed homozygote decreased locomotor activity 5.0727412599371746E-5
Ces2e
Ces2eem1(IMPC)Marc
Hematology Hemoglobin homozygote Female decreased hemoglobin content 5.1877716032322496E-5
Uchl5
Uchl5tm1(NCOM)Mfgc
Open Field Whole arena resting time heterozygote Male decreased locomotor activity 5.212371252127923E-5
Abhd3
Abhd3em1(IMPC)Marc
Echo Fractional Shortening homozygote decreased cardiac muscle contractility 5.248005618341267E-5
Trim37
Trim37em1(IMPC)Marc
Auditory Brain Stem Response 24kHz-evoked ABR Threshold homozygote abnormal auditory brainstem response 5.293107096804306E-5
Usp30
Usp30em1(IMPC)Marc
Auditory Brain Stem Response 24kHz-evoked ABR Threshold homozygote abnormal auditory brainstem response 5.293107096804306E-5
Prdm2
Prdm2em1(IMPC)Marc
Grip Strength Forelimb and hindlimb grip strength normalised against body weight homozygote Female increased grip strength 5.305982267600484E-5
Fbxo15
Fbxo15em1(IMPC)Marc
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 5.310939741320908E-5
Trim37
Trim37em1(IMPC)Marc
Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration homozygote Female increased fasting circulating glucose level 5.326139580574818E-5
Ppp1cc
Ppp1cctm1b(EUCOMM)Wtsi
Open Field Whole arena resting time homozygote Female decreased locomotor activity 5.341283031157218E-5
Cox8a
Cox8aem1(IMPC)Marc
Eye Morphology Retina (combined) homozygote abnormal retina morphology 5.370640064938925E-5
Ube2d3
Ube2d3tm1b(EUCOMM)Hmgu
Eye Morphology Retina (combined) heterozygote abnormal retina morphology 5.370640064938925E-5
Prmt6
Prmt6em1(IMPC)Marc
Eye Morphology Retina (combined) homozygote abnormal retina morphology 5.370640064938925E-5
Ppp2r5d
Ppp2r5dem2(IMPC)Marc
Eye Morphology Retina (combined) homozygote abnormal retina morphology 5.370640064938925E-5
Ccdc83
Ccdc83em1(IMPC)Marc
Eye Morphology Retina (combined) homozygote abnormal retina morphology 5.370640064938925E-5
Fbxo15
Fbxo15em1(IMPC)Marc
Eye Morphology Retina (combined) homozygote abnormal retina morphology 5.370640064938925E-5
Senp8
Senp8em1(IMPC)Marc
Eye Morphology Retina (combined) heterozygote abnormal retina morphology 5.370640064938925E-5
Hnrnpd
Hnrnpdtm1b(KOMP)Wtsi
Open Field Percentage center movement time heterozygote Female increased anxiety-related response 5.393117680796422E-5
Pan2
Pan2tm1b(KOMP)Wtsi
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 5.4357878980226815E-5
Snx25
Snx25tm1b(KOMP)Wtsi
Open Field Periphery distance travelled heterozygote Female hyperactivity 5.449471063911915E-5
Hilpda
Hilpdaem1(IMPC)Mhzh
Echo LVPWs homozygote decreased heart left ventricle size 5.4612301028100774E-5
Atg4b
Atg4bem1(IMPC)Marc
Clinical Chemistry Alanine aminotransferase homozygote increased circulating alanine transaminase level 5.4760766943218186E-5
Fbxo38
Fbxo38em2(IMPC)Marc
Open Field Whole arena average speed homozygote Male decreased locomotor activity 5.50955519429408E-5
Prpf31
Prpf31tm1a(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Fat mass heterozygote Male increased total body fat amount 5.540761776501313E-5
Ube2z
Ube2zem1(IMPC)Marc
Echo LVPWs heterozygote Female decreased heart left ventricle size 5.562083242693916E-5
Pfkfb2
Pfkfb2tm1b(KOMP)Wtsi
Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration homozygote Female increased fasting circulating glucose level 5.648602018482052E-5
Fntb
Fntbtm1b(EUCOMM)Hmgu
Hematology Platelet count heterozygote Male thrombocytopenia 5.70899028389249E-5
Hectd1
Hectd1tm1b(EUCOMM)Hmgu
Clinical Chemistry Alkaline phosphatase heterozygote Female decreased circulating alkaline phosphatase level 5.750741183874197E-5
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Open Field Center distance travelled heterozygote Male decreased locomotor activity 5.814145697513595E-5
Ezh1
Ezh1tm1b(EUCOMM)Wtsi
Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI1 homozygote Male decreased prepulse inhibition 5.834875628352165E-5
Ctsm
Ctsmtm1(KOMP)Wtsi
Hematology Mean cell hemoglobin concentration homozygote Male increased mean corpuscular hemoglobin concentration 5.861412500962615E-5
Ccdc83
Ccdc83em1(IMPC)Marc
Echo LVAWd homozygote decreased heart left ventricle size 5.908165258006193E-5
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Clinical Chemistry Phosphorus homozygote Female decreased circulating phosphate level 5.9515004977583885E-5
Defb43
Defb43tm1b(KOMP)Wtsi
Echo LVAWs homozygote Female thin ventricular wall 6.119460886111483E-5
Prmt6
Prmt6em1(IMPC)Marc
Hematology Eosinophil differential count homozygote Female increased eosinophil cell number 6.119695899542421E-5
Atg4a
Atg4aem2(IMPC)Marc
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) homozygote Male decreased bone mineral density 6.12266521784477E-5
Pan2
Pan2tm1b(KOMP)Wtsi
Heart Weight Heart weight homozygote Male increased heart weight 6.1304475821089E-5
Eddm3b
Eddm3btm1b(KOMP)Wtsi
Echo LVIDd homozygote Male dilated heart left ventricle 6.147736712591723E-5
Abhd3
Abhd3em1(IMPC)Marc
Echo LVIDs homozygote Male dilated heart left ventricle 6.176074384711683E-5
Dagla
Daglatm1a(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Body length homozygote Female decreased body length 6.205652607604861E-5
Usp39
Usp39tm1b(EUCOMM)Hmgu
Auditory Brain Stem Response Click-evoked ABR threshold heterozygote abnormal auditory brainstem response 6.348630267893896E-5
Abhd3
Abhd3em1(IMPC)Marc
Echo LVPWd homozygote Male thin ventricular wall 6.400913844117895E-5
Usp39
Usp39tm1b(EUCOMM)Hmgu
Combined SHIRPA and Dysmorphology Coat - color - head heterozygote abnormal coat/hair pigmentation 6.443351594498381E-5
Usp50
Usp50tm1(KOMP)Vlcg
Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI1 heterozygote Male decreased prepulse inhibition 6.512385152745992E-5
Fbxo10
Fbxo10tm1b(KOMP)Wtsi
Hematology Neutrophil cell count homozygote Male decreased neutrophil cell number 6.517455040011555E-5
Hectd3
Hectd3tm1(NCOM)Cmhd
Grip Strength Forelimb grip strength measurement mean homozygote Female decreased grip strength 6.529413076350465E-5
Suv39h2
Suv39h2em1(IMPC)Marc
Clinical Chemistry Triglycerides homozygote increased circulating triglyceride level 6.649053102592006E-5
Usp40
Usp40em1(IMPC)Marc
Body Composition (DEXA lean/fat) Fat/Body weight homozygote Male increased total body fat amount 6.662985833827406E-5
Fbxo36
Fbxo36tm1b(KOMP)Wtsi
Grip Strength Forelimb and hindlimb grip strength measurement mean homozygote Female decreased grip strength 6.786271114833653E-5
Fbxo28
Fbxo28em1(IMPC)Mhzh
Open Field Periphery permanence time heterozygote Female decreased thigmotaxis 6.844961899332702E-5
Fbxo28
Fbxo28em1(IMPC)Mhzh
Open Field Center permanence time heterozygote Female decreased thigmotaxis 6.848994235042483E-5
Fbxo28
Fbxo28em1(IMPC)Mhzh
Open Field Percentage center time heterozygote Female abnormal behavior 6.850584759376943E-5
Rabggta
Rabggtatm1.1(KOMP)Vlcg
Hematology Neutrophil differential count heterozygote Female decreased neutrophil cell number 6.855247920611873E-5
Usp15
Usp15em1(IMPC)Marc
Open Field Periphery distance travelled homozygote decreased locomotor activity 6.857412518002093E-5
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Open Field Center permanence time heterozygote Female increased thigmotaxis 6.926050991751254E-5
Ppp2r5e
Ppp2r5eem1(IMPC)Marc
Auditory Brain Stem Response 24kHz-evoked ABR Threshold homozygote abnormal auditory brainstem response 6.931604002602398E-5
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Open Field Percentage center time heterozygote Female abnormal behavior 6.965632201172411E-5
Cdc42ep5
Cdc42ep5tm1(KOMP)Wtsi
Body Composition (DEXA lean/fat) Lean mass homozygote Male decreased lean body mass 7.03242258168757E-5
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
Open Field Periphery permanence time heterozygote Female increased thigmotaxis 7.040241325739771E-5
Bbof1
Bbof1em1(IMPC)Marc
Clinical Chemistry Iron homozygote Female increased circulating iron level 7.050466228974983E-5
Herc6
Herc6tm1b(EUCOMM)Hmgu
Hematology Eosinophil cell count homozygote Male increased eosinophil cell number 7.069652929203585E-5
Ints6l
Ints6lem1(IMPC)Marc
Clinical Chemistry Phosphorus hemizygote decreased circulating phosphate level 7.087488484103233E-5
Bbc3
Bbc3em1(IMPC)Marc
Open Field Periphery average speed homozygote hyperactivity 7.105866097845137E-5
B3galt1
B3galt1em1(IMPC)Marc
Open Field Center distance travelled homozygote decreased locomotor activity 7.15754649718292E-5
Usp32
Usp32em1(IMPC)Mhzh
Hematology Red blood cell distribution width heterozygote Male increased red blood cell distribution width 7.278953125933185E-5
B3galt1
B3galt1em1(IMPC)Marc
Open Field Whole arena resting time homozygote Male decreased locomotor activity 7.45968718547374E-5
Fbxo38
Fbxo38em2(IMPC)Marc
Open Field Center resting time homozygote Male decreased locomotor activity 7.463515066774562E-5
Ctsm
Ctsmtm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Locomotor activity homozygote Male decreased exploration in new environment 7.653204374946654E-5
Ube2d3
Ube2d3tm1b(EUCOMM)Hmgu
Open Field Periphery average speed heterozygote decreased locomotor activity 7.679561531404033E-5
Ppp2r5e
Ppp2r5eem1(IMPC)Marc
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) homozygote Female decreased bone mineral content 7.701354479650036E-5
Ube2d3
Ube2d3tm1b(EUCOMM)Hmgu
Open Field Distance travelled - total heterozygote decreased locomotor activity 7.76115120970644E-5
Fbxw8
Fbxw8tm1b(EUCOMM)Hmgu
Clinical Chemistry Creatinine heterozygote Male increased circulating creatinine level 7.792857650201768E-5
Prdm2
Prdm2em1(IMPC)Marc
Hematology Hematocrit homozygote Male decreased hematocrit 7.883607759140432E-5
Vav2
Vav2em1(IMPC)Marc
Hematology Eosinophil cell count homozygote increased eosinophil cell number 7.900413766037673E-5
Usp46
Usp46em1(IMPC)Marc
Hematology Mean cell volume homozygote increased mean corpuscular volume 7.908334373496473E-5
Ppp2r2a
Ppp2r2atm1b(KOMP)Wtsi
Body Composition (DEXA lean/fat) Lean/Body weight heterozygote Male decreased lean body mass 7.939890929264948E-5
Ppp2r5e
Ppp2r5eem1(IMPC)Marc
Open Field Distance travelled - total homozygote Female decreased locomotor activity 7.982641545822844E-5
Usp43
Usp43em1(IMPC)Marc
Grip Strength Forelimb grip strength measurement mean homozygote Male decreased grip strength 7.994537736522034E-5
Ankle1
Ankle1tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Coat - color - back homozygote Male abnormal coat/hair pigmentation 8.028338197618723E-5
Dusp7
Dusp7tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Coat - color - back homozygote Male abnormal coat/hair pigmentation 8.028338197618723E-5
Alg1
Alg1tm1b(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Coat - color - back heterozygote Male abnormal coat/hair pigmentation 8.028338197618723E-5
Fbxo38
Fbxo38em2(IMPC)Marc
Open Field Periphery average speed homozygote Male decreased locomotor activity 8.0881203757599E-5
Usp15
Usp15em1(IMPC)Marc
Open Field Center average speed homozygote Male decreased locomotor activity 8.124014129862189E-5
Fbxo22
Fbxo22tm1b(EUCOMM)Wtsi
Echo LVAWd heterozygote decreased heart left ventricle size 8.130952483043075E-5
Emc4
Emc4tm1(KOMP)Wtsi
Echo LVPWs heterozygote Female decreased heart left ventricle size 8.240524039138108E-5
Atg4b
Atg4bem1(IMPC)Marc
Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration homozygote increased fasting circulating glucose level 8.244205673690885E-5
Lhcgr
Lhcgrtm1(KOMP)Vlcg
Hematology Mean cell volume homozygote Female decreased mean corpuscular volume 8.270744001492858E-5
Usp32
Usp32em1(IMPC)Mhzh
Clinical Chemistry Albumin heterozygote Male decreased circulating serum albumin level 8.325672388309613E-5
Ash1l
Ash1ltm2b(EUCOMM)Hmgu
Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration heterozygote increased fasting circulating glucose level 8.349513518624008E-5
Atg4d
Atg4dem1(IMPC)Marc
Open Field Percentage center time homozygote Female abnormal behavior 8.364333189092577E-5
Atg4d
Atg4dem1(IMPC)Marc
Open Field Center permanence time homozygote Female increased thigmotaxis 8.364906534552574E-5
Herc6
Herc6tm1b(EUCOMM)Hmgu
Hematology Platelet count homozygote Male thrombocytopenia 8.36835679365322E-5
Atg4d
Atg4dem1(IMPC)Marc
Open Field Periphery permanence time homozygote Female increased thigmotaxis 8.391038863919675E-5
Otud3
Otud3em1(IMPC)Marc
Hematology Monocyte cell count homozygote Male increased monocyte cell number 8.391579467570409E-5
Ezh1
Ezh1tm1b(EUCOMM)Wtsi
Hematology Red blood cell distribution width homozygote Male decreased red blood cell distribution width 8.399007492698729E-5
Ezh1
Ezh1tm1b(EUCOMM)Wtsi
Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI3 homozygote Male decreased prepulse inhibition 8.400752994930372E-5
Hnrnpd
Hnrnpdtm1b(KOMP)Wtsi
Open Field Number of center entries heterozygote decreased locomotor activity 8.423720282735303E-5
Fbxo10
Fbxo10tm1b(KOMP)Wtsi
Clinical Chemistry Glucose homozygote Male decreased circulating glucose level 8.436518692178652E-5
Usp39
Usp39tm1b(EUCOMM)Hmgu
Combined SHIRPA and Dysmorphology Coat - color - abdomen heterozygote abnormal coat/hair pigmentation 8.441014506388456E-5
Hectd3
Hectd3tm1(NCOM)Cmhd
Body Composition (DEXA lean/fat) Fat mass homozygote Female increased total body fat amount 8.47115006763488E-5
Hectd3
Hectd3tm1(NCOM)Cmhd
Echo Fractional Shortening homozygote Female increased cardiac muscle contractility 8.531017374480143E-5
Zswim1
Zswim1tm1b(KOMP)Mbp
Hematology Mean cell hemoglobin concentration homozygote Male increased mean corpuscular hemoglobin concentration 8.538776455679908E-5
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Clinical Chemistry Alkaline phosphatase homozygote Male increased circulating alkaline phosphatase level 8.677248115418479E-5
Oxsm
Oxsmem2(IMPC)Marc
Auditory Brain Stem Response 24kHz-evoked ABR Threshold heterozygote abnormal auditory brainstem response 8.745133527554572E-5
Bod1
Bod1tm1b(KOMP)Wtsi
Auditory Brain Stem Response 24kHz-evoked ABR Threshold heterozygote abnormal auditory brainstem response 8.745133527554572E-5
Defb43
Defb43tm1b(KOMP)Wtsi
Auditory Brain Stem Response 24kHz-evoked ABR Threshold homozygote abnormal auditory brainstem response 8.745133527554572E-5
Fbxo24
Fbxo24em2(IMPC)Marc
Auditory Brain Stem Response 24kHz-evoked ABR Threshold homozygote abnormal auditory brainstem response 8.745133527554572E-5
Dctd
Dctdem1(IMPC)Marc
Auditory Brain Stem Response 24kHz-evoked ABR Threshold homozygote abnormal auditory brainstem response 8.745133527554572E-5
Usp43
Usp43em1(IMPC)Marc
Auditory Brain Stem Response 24kHz-evoked ABR Threshold homozygote abnormal auditory brainstem response 8.745133527554572E-5
Ppp1r14a
Ppp1r14aem1(IMPC)Marc
Auditory Brain Stem Response 24kHz-evoked ABR Threshold homozygote abnormal auditory brainstem response 8.745133527554572E-5
Fbxl15
Fbxl15em1(IMPC)Marc
Auditory Brain Stem Response 24kHz-evoked ABR Threshold homozygote abnormal auditory brainstem response 8.745133527554572E-5
Fbxl8
Fbxl8em2(IMPC)Marc
Auditory Brain Stem Response 24kHz-evoked ABR Threshold homozygote abnormal auditory brainstem response 8.745133527554572E-5
Akr1c12
Akr1c12tm1b(KOMP)Wtsi
Auditory Brain Stem Response 24kHz-evoked ABR Threshold homozygote abnormal auditory brainstem response 8.745133527554572E-5
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Auditory Brain Stem Response 24kHz-evoked ABR Threshold homozygote abnormal auditory brainstem response 8.745133527554572E-5
Fam166b
Fam166btm1(KOMP)Wtsi
Auditory Brain Stem Response 24kHz-evoked ABR Threshold homozygote abnormal auditory brainstem response 8.745133527554572E-5
Bap1
Bap1em2(IMPC)Marc
Auditory Brain Stem Response 24kHz-evoked ABR Threshold heterozygote abnormal auditory brainstem response 8.745133527554572E-5
Ube2w
Ube2wtm1b(EUCOMM)Wtsi
Auditory Brain Stem Response 24kHz-evoked ABR Threshold homozygote abnormal auditory brainstem response 8.745133527554572E-5
Atg4b
Atg4bem1(IMPC)Marc
Auditory Brain Stem Response 24kHz-evoked ABR Threshold homozygote abnormal auditory brainstem response 8.745133527554572E-5
Hectd1
Hectd1tm1b(EUCOMM)Hmgu
Combined SHIRPA and Dysmorphology Coat - color pattern - abdomen heterozygote Female abnormal coat/hair pigmentation 8.758101466810331E-5
Mir320
Mir320tm1(mirKO)Wtsi
Combined SHIRPA and Dysmorphology Tail - thickness heterozygote Female abnormal tail morphology 8.758101466810331E-5
Phf5a
Phf5aem2(IMPC)Marc
Hematology Red blood cell distribution width heterozygote Female increased red blood cell distribution width 8.85900590219535E-5
Kdm2b
Kdm2bem1(IMPC)Marc
Clinical Chemistry Glucose heterozygote decreased circulating glucose level 8.875932689988986E-5
B3galt1
B3galt1em1(IMPC)Marc
Open Field Latency to center entry homozygote Male decreased exploration in new environment 8.966147288447246E-5
Fbxl5
Fbxl5em1(IMPC)Marc
Clinical Chemistry Aspartate aminotransferase heterozygote decreased circulating aspartate transaminase level 8.983619773061946E-5
Bcl2l13
Bcl2l13em1(IMPC)Marc
Hematology Lymphocyte cell count homozygote Female decreased lymphocyte cell number 9.020359721034765E-5
Ppp2r5e
Ppp2r5eem1(IMPC)Marc
Open Field Center average speed homozygote Female decreased locomotor activity 9.14947668206878E-5
Alg1
Alg1tm1b(KOMP)Wtsi
Hematology White blood cell count heterozygote Female increased leukocyte cell number 9.162191417999566E-5
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Clinical Chemistry Total cholesterol homozygote Female increased circulating cholesterol level 9.172682621283457E-5
Fbxo2
Fbxo2tm1b(EUCOMM)Wtsi
Open Field Periphery resting time homozygote Female decreased locomotor activity 9.182915528072044E-5
Mir320
Mir320tm1(mirKO)Wtsi
Combined SHIRPA and Dysmorphology Tail - length heterozygote Female abnormal tail length 9.197309555020183E-5
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
Open Field Whole arena average speed homozygote Female decreased locomotor activity 9.284444968216121E-5
Usp32
Usp32em1(IMPC)Mhzh
Hematology White blood cell count heterozygote Male increased leukocyte cell number 9.297134238295257E-5
Ube2z
Ube2zem1(IMPC)Marc
Hematology Mean platelet volume heterozygote Male increased mean platelet volume 9.301445970777422E-5
Mast1
Mast1em1(IMPC)Marc
Heart Weight Heart weight homozygote Male decreased heart weight 9.391219646204263E-5
Phf3
Phf3em2(IMPC)Marc
Combined SHIRPA and Dysmorphology Startle response homozygote Male abnormal startle reflex 9.454732207814232E-5
Fshr
Fshrtm1(KOMP)Vlcg
Combined SHIRPA and Dysmorphology Startle response homozygote Male abnormal startle reflex 9.454732207814232E-5
Hilpda
Hilpdaem1(IMPC)Mhzh
Echo Fractional Shortening homozygote Female decreased cardiac muscle contractility 9.529420640319586E-5
Trim37
Trim37em1(IMPC)Marc
Grip Strength Forelimb and hindlimb grip strength measurement mean homozygote increased grip strength 9.538838639855385E-5
Abhd3
Abhd3em1(IMPC)Marc
Open Field Center resting time homozygote decreased locomotor activity 9.600157500244677E-5
Mir350
Mir350tm1(mirKO)Wtsi
Echo LVIDs homozygote abnormal heart left ventricle morphology 9.613747533876449E-5
Ints6l
Ints6lem1(IMPC)Marc
Clinical Chemistry Triglycerides hemizygote increased circulating triglyceride level 9.653640881879255E-5
Zfp36
Zfp36tm1(KOMP)Vlcg
Hematology White blood cell count heterozygote Female increased leukocyte cell number 9.686242265161127E-5
Fbxo2
Fbxo2tm1b(EUCOMM)Wtsi
Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration homozygote Female decreased fasting circulating glucose level 9.773481724550948E-5
Ppp2r5e
Ppp2r5eem1(IMPC)Marc
Hematology Mean platelet volume homozygote Female decreased mean platelet volume 9.783279529074207E-5
Ap5z1
Ap5z1tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Head morphology homozygote abnormal head morphology 9.847206092672423E-5
Ppp2r1b
Ppp2r1btm1b(EUCOMM)Wtsi
Combined SHIRPA and Dysmorphology Lower teeth appearance homozygote abnormal tooth morphology 9.847206092672423E-5
Phf21b
Phf21bem1(IMPC)Marc
Hematology Basophil differential count homozygote increased basophil cell number 9.912026871461421E-5
Ezh1
Ezh1tm1b(EUCOMM)Wtsi
Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI2 homozygote Male decreased prepulse inhibition 9.920941374730319E-5
Atg4c
Atg4cem2(IMPC)Marc
Body Composition (DEXA lean/fat) Bone Area homozygote Female abnormal bone structure 9.93548528640531E-5
Cox8a
Cox8aem1(IMPC)Marc
Grip Strength Forelimb grip strength normalised against body weight homozygote Male decreased grip strength 9.962953481590375E-5

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