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Phenotype: increased kidney weight

Definition
greater weight of the organs responsible for urine secretion
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased kidney weight

Total number of significant genotype-phenotype associations: 51

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Hmx2
Hmx2tm1.1(KOMP)Vlcg 		HOM   Early adult increased kidney weight Left kidney
Organ Weight		 UC Davis
IMPC		 5.85×10-41
Slc3a1
Slc3a1tm1.1(KOMP)Vlcg 		HOM   Early adult increased kidney weight Right kidney
Organ Weight		 UC Davis
IMPC		 3.16×10-20
Col4a3
Col4a3tm1b(EUCOMM)Wtsi 		HOM Early adult increased kidney weight Left kidney
Organ Weight		 MRC Harwell
IMPC		 1.46×10-18
Gcgr
Gcgrtm1.1(KOMP)Vlcg 		HOM   Early adult increased kidney weight Right kidney
Organ Weight		 UC Davis
IMPC		 1.78×10-15
Gja8
Gja8tm1b(EUCOMM)Hmgu 		HOM Early adult increased kidney weight Left kidney
Organ Weight		 MRC Harwell
IMPC		 1.05×10-13
Coa6
Coa6em1(IMPC)Ccpcz 		HET Early adult increased kidney weight Left kidney weight
Organ Weight		 CCP-IMG
IMPC		 3.47×10-13
Fam120c
Fam120cem1(IMPC)Ccpcz 		HEM   Early adult increased kidney weight Right kidney weight
Organ Weight		 CCP-IMG
IMPC		 3.93×10-13
Abcc2
Abcc2tm2b(KOMP)Wtsi 		HOM Early adult increased kidney weight Left kidney
Organ Weight		 MRC Harwell
IMPC		 3.18×10-12
Sik1
Sik1tm1.1(KOMP)Vlcg 		HOM   Early adult increased kidney weight Right kidney
Organ Weight		 UC Davis
IMPC		 7.94×10-12
Krtap9-5
Krtap9-5em1(IMPC)Ccpcz 		HOM Early adult increased kidney weight Right kidney weight
Organ Weight		 CCP-IMG
IMPC		 6.24×10-11
Grm6
Grm6tm1b(EUCOMM)Wtsi 		HOM Early adult increased kidney weight Left kidney
Organ Weight		 MRC Harwell
IMPC		 2.75×10-10
Agl
Agltm1b(EUCOMM)Wtsi 		HOM   Early adult increased kidney weight Left kidney
Organ Weight		 MRC Harwell
IMPC		 1.94×10-09
Ap4e1
Ap4e1tm1b(KOMP)Wtsi 		HOM   Early adult increased kidney weight Left kidney
Organ Weight		 UC Davis
IMPC		 3.38×10-09
Fads1
Fads1tm1.1(KOMP)Vlcg 		HOM   Early adult increased kidney weight Left kidney
Organ Weight		 UC Davis
IMPC		 9.42×10-09
Wdhd1
Wdhd1em1(IMPC)Rbrc 		HET Late adult increased kidney weight Right kidney weight
Organ Weight		 RBRC
IMPC		 1.60×10-08
Myo1g
Myo1gem1(IMPC)Ccpcz 		HOM Early adult increased kidney weight Left kidney weight
Organ Weight		 CCP-IMG
IMPC		 1.76×10-08
Lor
Lortm1.1(KOMP)Vlcg 		HOM   Early adult increased kidney weight Right kidney
Organ Weight		 UC Davis
IMPC		 4.19×10-08
Krtap17-1
Krtap17-1tm1.1(KOMP)Vlcg 		HOM   Early adult increased kidney weight Right kidney
Organ Weight		 UC Davis
IMPC		 8.15×10-08
Clstn3
Clstn3tm1b(EUCOMM)Hmgu 		HOM Early adult increased kidney weight Left kidney
Organ Weight		 MRC Harwell
IMPC		 8.59×10-08
Mbd6
Mbd6tm1.1(KOMP)Vlcg 		HET   Early adult increased kidney weight Right kidney
Organ Weight		 UC Davis
IMPC		 2.60×10-07
Siglec1
Siglec1tm1.1(KOMP)Vlcg 		HOM   Early adult increased kidney weight Right kidney
Organ Weight		 UC Davis
IMPC		 5.73×10-07
Lor
Lortm1.1(KOMP)Vlcg 		HET   Early adult increased kidney weight Right kidney
Organ Weight		 UC Davis
IMPC		 7.08×10-07
Pstpip1
Pstpip1em1(IMPC)Ccpcz 		HOM Early adult increased kidney weight Right kidney weight
Organ Weight		 CCP-IMG
IMPC		 1.84×10-06
Gpld1
Gpld1tm1.1(KOMP)Vlcg 		HOM   Early adult increased kidney weight Right kidney
Organ Weight		 UC Davis
IMPC		 2.87×10-06
Plppr5
Plppr5em1(IMPC)Ccpcz 		HOM Early adult increased kidney weight Right kidney weight
Organ Weight		 CCP-IMG
IMPC		 2.87×10-06
Spink13
Spink13em1(IMPC)Ccpcz 		HOM Early adult increased kidney weight Left kidney weight
Organ Weight		 CCP-IMG
IMPC		 3.15×10-06
Tmem115
Tmem115tm1(KOMP)Vlcg 		HET   Early adult increased kidney weight Right kidney
Organ Weight		 UC Davis
IMPC		 3.75×10-06
Caskin2
Caskin2tm1.1(KOMP)Vlcg 		HOM   Early adult increased kidney weight Left kidney
Organ Weight		 UC Davis
IMPC		 4.07×10-06
Zzef1
Zzef1tm2.1(KOMP)Vlcg 		HOM   Early adult increased kidney weight Right kidney
Organ Weight		 UC Davis
IMPC		 5.67×10-06
Elmod1
Elmod1tm1b(EUCOMM)Hmgu 		HOM Early adult increased kidney weight Right kidney
Organ Weight		 MRC Harwell
IMPC		 7.22×10-06
Fdx2
Fdx2em1(IMPC)Rbrc 		HOM Late adult increased kidney weight Right kidney weight
Organ Weight		 RBRC
IMPC		 1.04×10-05
Marveld3
Marveld3em1(IMPC)Ccpcz 		HOM Early adult increased kidney weight Left kidney weight
Organ Weight		 CCP-IMG
IMPC		 1.08×10-05
Lrig3
Lrig3em1(IMPC)Ccpcz 		HOM Early adult increased kidney weight Right kidney weight
Organ Weight		 CCP-IMG
IMPC		 1.09×10-05
Etv6
Etv6em1(IMPC)Rbrc 		HET Late adult increased kidney weight Left kidney weight
Organ Weight		 RBRC
IMPC		 1.26×10-05
Rab32
Rab32tm1b(KOMP)Wtsi 		HOM   Early adult increased kidney weight Right kidney
Organ Weight		 UC Davis
IMPC		 1.36×10-05
Fkbp5
Fkbp5tm1b(KOMP)Wtsi 		HOM   Early adult increased kidney weight Right kidney
Organ Weight		 UC Davis
IMPC		 1.50×10-05
Fbxo41
Fbxo41tm1.1(KOMP)Vlcg 		HOM   Early adult increased kidney weight Left kidney
Organ Weight		 UC Davis
IMPC		 1.76×10-05
Rbmx
Rbmxtm2b(KOMP)Wtsi 		HEM   Early adult increased kidney weight Right kidney
Organ Weight		 UC Davis
IMPC		 1.84×10-05
Hipk2
Hipk2tm2b(EUCOMM)Hmgu 		HET Early adult increased kidney weight Left kidney
Organ Weight		 MRC Harwell
IMPC		 1.85×10-05
Asb7
Asb7em1(IMPC)Ccpcz 		HOM Early adult increased kidney weight Right kidney weight
Organ Weight		 CCP-IMG
IMPC		 2.11×10-05
Psmb11
Psmb11em1(IMPC)Ccpcz 		HOM Early adult increased kidney weight Right kidney weight
Organ Weight		 CCP-IMG
IMPC		 2.16×10-05
Mapkbp1
Mapkbp1tm1b(EUCOMM)Hmgu 		HOM Early adult increased kidney weight Right kidney
Organ Weight		 MRC Harwell
IMPC		 3.64×10-05
Mid1ip1
Mid1ip1tm1.1(KOMP)Vlcg 		HEM   Early adult increased kidney weight Left kidney
Organ Weight		 UC Davis
IMPC		 4.22×10-05
Rnft1
Rnft1em1(IMPC)Ccpcz 		HOM Early adult increased kidney weight Left kidney weight
Organ Weight		 CCP-IMG
IMPC		 4.26×10-05
Apbb1ip
Apbb1ipem1(IMPC)Ccpcz 		HOM Early adult increased kidney weight Right kidney weight
Organ Weight		 CCP-IMG
IMPC		 4.50×10-05
Fkbp5
Fkbp5tm1b(KOMP)Wtsi 		HET   Early adult increased kidney weight Right kidney
Organ Weight		 UC Davis
IMPC		 7.39×10-05
F10
F10tm1b(EUCOMM)Hmgu 		HET Early adult increased kidney weight Right kidney
Organ Weight		 MRC Harwell
IMPC		 7.47×10-05
Dock11
Dock11tm2b(KOMP)Wtsi 		HEM   Early adult increased kidney weight Left kidney
Organ Weight		 UC Davis
IMPC		 7.91×10-05
Lipe
Lipetm1b(KOMP)Wtsi 		HOM   Early adult increased kidney weight Left kidney
Organ Weight		 UC Davis
IMPC		 8.19×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Organ Weight

 Phenotype associations stats

2.66% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased kidney weight (47/1765)

1.35% females (7/520) 1.69% males (19/1126)

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