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Phenotype: increased hemoglobin content

Definition
increase in the total hemoglobin content in the circulating blood
Synonyms
increased haemoglobin content
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased hemoglobin content

Total number of significant genotype-phenotype associations: 92

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Hmcn2
Hmcn2tm1b(EUCOMM)Wtsi 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 BCM
IMPC		 2.27×10-12
Dll1
Dll1tm1Gos 		HET Early adult increased hemoglobin content Hemoglobin
Haematology (GMC)		 HMGU
EuroPhenome		 1.30×10-11
Lepr
Leprtm1b(EUCOMM)Wtsi 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 MRC Harwell
IMPC		 5.33×10-11
Rnf43
Rnf43em1(IMPC)Tcp 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 TCP
IMPC		 1.45×10-09
Tppp
Tppptm1.1(KOMP)Vlcg 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 3.68×10-09
Stk16
Stk16tm1.1(KOMP)Vlcg 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 8.32×10-09
Cfb
Cfbtm1.1(KOMP)Wtsi 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 1.12×10-08
Fam163a
Fam163atm2b(KOMP)Wtsi 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 WTSI
IMPC		 2.68×10-08
Ubac1
Ubac1em1(IMPC)J 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 3.12×10-08
Phkg2
Phkg2tm1.1(KOMP)Vlcg 		HET Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 3.56×10-08
Nptn
Nptntm1b(EUCOMM)Hmgu 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 MRC Harwell
IMPC		 1.54×10-07
Bmp6
Bmp6em1(IMPC)Ccpcz 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 CCP-IMG
IMPC		 2.69×10-07
Mybbp1a
Mybbp1atm1b(EUCOMM)Hmgu 		HET Early adult increased hemoglobin content Hemoglobin
Hematology		 HMGU
IMPC		 3.66×10-07
Pde4dip
Pde4diptm1b(KOMP)Wtsi 		HET Early adult increased hemoglobin content Hemoglobin
Hematology		 BCM
IMPC		 4.37×10-07
Zfp689
Zfp689tm1.1(KOMP)Vlcg 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 4.90×10-07
Dock6
Dock6em1(IMPC)J 		HET Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 6.20×10-07
Cops4
Cops4tm1a(EUCOMM)Hmgu 		HET Early adult increased hemoglobin content Mean cell haemoglobin concentration
Haematology		 ICS
EuroPhenome		 6.28×10-07
Mysm1
Mysm1tm1a(KOMP)Wtsi 		HOM Early adult increased hemoglobin content Mean cell haemoglobin concentration
Haematology		 WTSI
EuroPhenome		 8.14×10-07
Slc4a10
Slc4a10tm1b(KOMP)Wtsi 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 MRC Harwell
IMPC		 9.98×10-07
Jup
Juptm1.1(KOMP)Vlcg 		HET Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 1.58×10-06
Snx5
Snx5Snx5 		HOM Early adult increased hemoglobin content Mean cell haemoglobin concentration
Haematology		 ICS
EuroPhenome		 2.43×10-06
Cav1
Cav1em2(IMPC)Ics 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 ICS
IMPC		 2.79×10-06
Tcaf2
Tcaf2em1(IMPC)Ccpcz 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 CCP-IMG
IMPC		 2.90×10-06
Rabggta
Rabggtatm1.1(KOMP)Vlcg 		HET Early adult increased hemoglobin content Hemoglobin
Hematology		 MARC
IMPC		 2.96×10-06
Nsf
Nsftm1b(KOMP)Mbp 		HET Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 3.08×10-06
Ubl7
Ubl7em1(IMPC)Tcp 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 TCP
IMPC		 3.26×10-06
Rxfp2
Rxfp2tm1b(EUCOMM)Wtsi 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 HMGU
IMPC		 3.91×10-06
Atl2
Atl2tm2b(EUCOMM)Hmgu 		HET Early adult increased hemoglobin content Hemoglobin
Hematology		 MRC Harwell
IMPC		 3.92×10-06
Clpp
Clpptm1a(EUCOMM)Wtsi 		HOM   Early adult increased hemoglobin content Hemoglobin
Hematology		 WTSI
IMPC		 5.06×10-06
Ydjc
Ydjctm1.1(KOMP)Vlcg 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 5.09×10-06
Lmod3
Lmod3em1(IMPC)Mbp 		HET Late adult increased hemoglobin content Hemoglobin
Hematology		 UC Davis
IMPC		 5.11×10-06
Smarcal1
Smarcal1tm1a(EUCOMM)Wtsi 		HOM   Early adult increased hemoglobin content Haemoglobin
Haematology test		 WTSI
MGP		 5.24×10-06
Ahrr
Ahrrtm1b(KOMP)Wtsi 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 5.84×10-06
Fpr3
Fpr3tm1b(EUCOMM)Hmgu 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 ICS
IMPC		 6.84×10-06
Fahd2a
Fahd2atm1a(EUCOMM)Wtsi 		HOM Early adult increased hemoglobin content Haemoglobin
Haematology test		 WTSI
MGP		 7.02×10-06
Zfp760
Zfp760tm1a(EUCOMM)Hmgu 		HET Early adult increased hemoglobin content Haemoglobin
Haematology		 HMGU
EuroPhenome		 7.37×10-06
Gtpbp10
Gtpbp10tm1b(KOMP)Mbp 		HOM   Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 8.38×10-06
Ucp1
Ucp1m1H 		HOM   Early adult increased hemoglobin content Haemoglobin
Haematology		 MRC Harwell
EuroPhenome		 9.91×10-06
Ptpn2
Ptpn2tm1a(EUCOMM)Wtsi 		HET   Early adult increased hemoglobin content Haemoglobin
Haematology test		 WTSI
MGP		 9.93×10-06
Krt32
Krt32em1(IMPC)Kmpc 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 KMPC
IMPC		 1.07×10-05
Il24
Il24tm1.1(KOMP)Vlcg 		HOM   Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 1.43×10-05
Stau2
Stau2em1(IMPC)Mbp 		HOM   Early adult increased hemoglobin content Hemoglobin
Hematology		 UC Davis
IMPC		 1.44×10-05
Pik3cb
Pik3cbtm1a(EUCOMM)Wtsi 		HET Early adult increased hemoglobin content Haemoglobin
Haematology test		 WTSI
MGP		 1.97×10-05
Keg1
Keg1tm1b(KOMP)Mbp 		HOM   Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 2.10×10-05
Fbxl2
Fbxl2em2(IMPC)Marc 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 MARC
IMPC		 2.13×10-05
Tmem72
Tmem72tm1b(KOMP)Wtsi 		HOM   Early adult increased hemoglobin content Hemoglobin
Hematology		 KMPC
IMPC		 2.20×10-05
Kctd11
Kctd11em1(IMPC)J 		HOM   Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 2.24×10-05
Nr0b1
Nr0b1em2(IMPC)Wtsi 		HEM   Early adult increased hemoglobin content Hemoglobin
Hematology		 WTSI
IMPC		 2.25×10-05
Zfp536
Zfp536tm1.1(KOMP)Wtsi 		HET Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 2.37×10-05
Gpalpp1
Gpalpp1em1(IMPC)Hmgu 		HOM   Early adult increased hemoglobin content Hemoglobin
Hematology		 HMGU
IMPC		 2.44×10-05
Hsf2bp
Hsf2bptm1a(EUCOMM)Hmgu 		HOM Early adult increased hemoglobin content Haemoglobin
Haematology		 HMGU
EuroPhenome		 2.55×10-05
Tfr2
Tfr2em1(IMPC)Rbrc 		HOM   Early adult increased hemoglobin content Hemoglobin
Hematology		 RBRC
IMPC		 2.67×10-05
Svep1
Svep1tm1b(EUCOMM)Hmgu 		HET Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 2.67×10-05
Adcy3
Adcy3tm1a(EUCOMM)Wtsi 		HET Early adult increased hemoglobin content Hemoglobin
Hematology		 WTSI
IMPC		 2.77×10-05
Cyb561
Cyb561tm1a(EUCOMM)Wtsi 		HOM   Early adult increased hemoglobin content Haemoglobin
Haematology test		 WTSI
MGP		 3.17×10-05
Myh1
Myh1tm1b(KOMP)Wtsi 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 3.39×10-05
Idh2
Idh2tm1b(EUCOMM)Hmgu 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 MRC Harwell
IMPC		 3.77×10-05
Bag1
Bag1tm1a(EUCOMM)Hmgu 		HOM   Early adult increased hemoglobin content Mean cell haemoglobin concentration
Haematology		 ICS
EuroPhenome		 3.92×10-05
Prom2
Prom2tm1.1(KOMP)Vlcg 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 3.95×10-05
Vegfb
Vegfbtm1b(EUCOMM)Hmgu 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 4.41×10-05
Zfp641
Zfp641em1(IMPC)J 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 4.61×10-05
Pik3cb
Pik3cbtm1a(EUCOMM)Wtsi 		HOM Early adult increased hemoglobin content Haemoglobin
Haematology test		 WTSI
MGP		 4.73×10-05
Gpnmb
Gpnmbtm1.1(KOMP)Vlcg 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 4.94×10-05
Pkn1
Pkn1tm1b(KOMP)Wtsi 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 MRC Harwell
IMPC		 5.19×10-05
Rft1
Rft1tm1b(KOMP)Wtsi 		HET Early adult increased hemoglobin content Hemoglobin
Hematology		 MRC Harwell
IMPC		 5.27×10-05
Macrod2
Macrod2tm1.1(KOMP)Vlcg 		HOM   Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 5.40×10-05
Ap4e1
Ap4e1tm1b(KOMP)Wtsi 		HOM   Early adult increased hemoglobin content Hemoglobin
Hematology		 CCP-IMG
IMPC		 5.58×10-05
Chn1
Chn1tm1.1(KOMP)Vlcg 		HOM   Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 5.59×10-05
Krt17
Krt17tm1.1(KOMP)Vlcg 		HET   Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 5.68×10-05
Kcnh3
Kcnh3tm1.1(KOMP)Vlcg 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 6.08×10-05
Pdgfrl
Pdgfrlem1(IMPC)J 		HOM   Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 6.37×10-05
Ankrd13a
Ankrd13aGt(RRH308)Byg 		HOM Early adult increased hemoglobin content Mean cell haemoglobin concentration
Haematology		 WTSI
MGP		 6.45×10-05
Cldn13
Cldn13tm1.1(KOMP)Vlcg 		HOM   Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 6.51×10-05
Emp3
Emp3Emp3 		HOM   Early adult increased hemoglobin content Mean cell haemoglobin concentration
Haematology		 HMGU
EuroPhenome		 6.71×10-05
Dhps
Dhpstm2a(EUCOMM)Wtsi 		HET Early adult increased hemoglobin content Hemoglobin
Hematology		 WTSI
IMPC		 6.73×10-05
Arhgef1
Arhgef1tm1a(EUCOMM)Wtsi 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 WTSI
IMPC		 6.83×10-05
Trp53bp2
Trp53bp2tm1b(EUCOMM)Hmgu 		HET Early adult increased hemoglobin content Hemoglobin
Hematology		 MRC Harwell
IMPC		 6.88×10-05
Elmod2
Elmod2tm1b(EUCOMM)Hmgu 		HET Early adult increased hemoglobin content Hemoglobin
Hematology		 MRC Harwell
IMPC		 7.00×10-05
Ccdc183
Ccdc183em1(IMPC)Hmgu 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 HMGU
IMPC		 7.31×10-05
Daam2
Daam2tm1b(KOMP)Wtsi 		HOM   Early adult increased hemoglobin content Hemoglobin
Hematology		 MRC Harwell
IMPC		 7.70×10-05
Hjv
Hjvtm1b(KOMP)Wtsi 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 8.12×10-05
Mrpl3
Mrpl3em1(IMPC)J 		HET   Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 8.25×10-05
Bbs5
Bbs5tm1b(EUCOMM)Wtsi 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 MRC Harwell
IMPC		 8.31×10-05
Gprc6a
Gprc6atm1.1(KOMP)Vlcg 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 UC Davis
IMPC		 8.80×10-05
Asb10
Asb10tm2b(KOMP)Wtsi 		HOM Early adult increased hemoglobin content Hemoglobin
Hematology		 JAX
IMPC		 9.49×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Haematology
Haematology (GMC)
Haematology test
Hematology

 Phenotype associations stats

1.21% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased hemoglobin content (84/6969)

0.47% females (31/6600) 0.54% males (36/6631)

Select a parameter    



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