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Phenotype: abnormal heart looping

Definition
any anomaly in the characteristic morphogenetic movements where the primitive heart tube loops asymmetrically during early development; this looping brings the primitive heart chambers into alignment preceding their future integration
Synonyms
abnormal cardiac looping
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with abnormal heart looping

Total number of significant genotype-phenotype associations: 32

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Bicc1
Bicc1em1(IMPC)Mbp 		HOM E9.5 abnormal heart looping Heart looping
Gross Morphology Embryo E9.5		 UC Davis
IMPC		 0.00
Flnc
Flncem1(IMPC)Bay 		HOM E9.5 abnormal heart looping Heart looping
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Fuz
Fuzem1(IMPC)Mbp 		HOM E9.5 abnormal heart looping Heart looping
Gross Morphology Embryo E9.5		 UC Davis
IMPC		 0.00
Glmn
Glmnem1(IMPC)Bay 		HOM E9.5 abnormal heart looping Heart looping
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Hyls1
Hyls1em1(IMPC)Tcp 		HOM E9.5 abnormal heart looping Heart looping
Gross Morphology Embryo E9.5		 TCP
IMPC		 0.00
Ift43
Ift43tm1b(EUCOMM)Hmgu 		HOM E9.5 abnormal heart looping Heart looping
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Ift52
Ift52em1(IMPC)Bay 		HOM E9.5 abnormal heart looping Heart looping
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Isyna1
Isyna1em1(IMPC)Bay 		HOM E9.5 abnormal heart looping Heart looping
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Krit1
Krit1tm1.1(KOMP)Vlcg 		HOM E9.5 abnormal heart looping Heart looping
Gross Morphology Embryo E9.5		 UC Davis
IMPC		 0.00
Ndufb5
Ndufb5em1(IMPC)Bay 		HOM E9.5 abnormal heart looping Heart looping
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Nr6a1
Nr6a1tm1b(EUCOMM)Wtsi 		HOM E9.5 abnormal heart looping Heart looping
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Pcgf1
Pcgf1tm1.1(KOMP)Vlcg 		HOM E9.5 abnormal heart looping Heart looping
Gross Morphology Embryo E9.5		 JAX
IMPC		 0.00
Pibf1
Pibf1tm1.1(KOMP)Vlcg 		HOM E9.5 abnormal heart looping Heart looping
Gross Morphology Embryo E9.5		 JAX
IMPC		 0.00
Pigq
Pigqtm2b(EUCOMM)Wtsi 		HOM E9.5 abnormal heart looping Heart looping
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Slc30a9
Slc30a9em1(IMPC)Bay 		HOM E9.5 abnormal heart looping Heart looping
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Tbx20
Tbx20em1(IMPC)Mbp 		HOM E9.5 abnormal heart looping Heart looping
Gross Morphology Embryo E9.5		 UC Davis
IMPC		 0.00
Tedc1
Tedc1em1(IMPC)Tcp 		HOM E9.5 abnormal heart looping Heart looping
Gross Morphology Embryo E9.5		 TCP
IMPC		 0.00
Tgds
Tgdsem1(IMPC)Mbp 		HOM E9.5 abnormal heart looping Heart looping
Gross Morphology Embryo E9.5		 UC Davis
IMPC		 0.00
Vcan
Vcanem2(IMPC)Mbp 		HOM E9.5 abnormal heart looping Heart looping
Gross Morphology Embryo E9.5		 UC Davis
IMPC		 0.00

Download data as:   TSV   XLS

 The way we measure

Procedure
Gross Morphology Embryo E12.5
Gross Morphology Embryo E9.5

 Phenotype associations stats

2.03% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal heart looping (19/936)

2.40% females (16/666) 2.41% males (16/664)

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