Welcome to our Help Pages!
The International Mouse Phenotyping Consortium (IMPC) is an international research infrastructure aiming to identify the function of every gene in the mouse genome by creating and phenotyping mouse knockout lines for each of the 20,000 or so protein-coding genes. Our database is continuously growing as data is being generated. All data and images are available to use, free of charge! The IMPC dataset is publicly available under the Creative Commons Attribution 4.0 International license (CC-BY 4.0).
What information can I find here?
Briefly, the data the IMPC is collecting allows to identify the physiological systems that are disrupted when a gene is disabled and thus generate gene-phenotype associations. For this purpose, the IMPC has developed specific in-house protocols for high-throughput mice production and tracking, phenotyping and data analysis. A brief description of the project can be found here, and consortium publications are listed here. The IMPC blog provides information on recent relevant publications, interviews and news.
How can I access the data?
This website captures, stores and disseminates the IMPC processes, data and annotations to the scientific community and the public. Users are able to search this data in several ways. You can specify a gene or phenotype of interest in the website search bar, which is available on all pages. For specific or bulk downloads, both Programmatic and Non Programmatic Data Access are supported.
How can I learn more?
We invite you to learn more about the IMPC through these pages, our webinar and our online training course. You may want to visit our Getting Started with IMPC data section. Our webinar provides an overview on IMPC findings as described in papers, including the description of the phenotyping pipelines, statistical analyses, and engagement with clinical and external consortia. Our online training course exemplifies IMPC website navigation and data accessing, with numerous website screenshots, videos, interactive content and a “try it yourself” activity.