How We Generate Our Data

  • Targeting genes that haven’t been studied yet
  • Standardised production methods to knock out genes
  • Mutants and wildtype mice tested under the same phenotyping protocols

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Understanding Our Data

  • We generate our own data, it is not aggregated from publications
  • A constantly growing dataset; mice continually tested
  • Data from 19 IMPC phenotyping centres, in 11 countries

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About the IMPC Project

The International Mouse Phenotyping Consortium (IMPC) is a global effort to identify the function of every protein-coding gene in the mouse genome. Our growing catalogue of mammalian gene function is freely available for researchers.

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Latest Data Release

Data release 10 has now been published. The number of phenotyped mutant lines has reached 6,255, bringing the total number of phenotyped genes to 5,861.

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Animal Welfare

The IMPC collects data from member institutes who collect phenotyping data guided by their own ethical review panels, licenses, and accrediting bodies that reflect the national and/or geo-political constructs in which they operate.

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We’re systematically phenotyping new knockout mice every day

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Horizon 2020 - Opportunities to Partner With The IMPC

Horizon 2020 is the biggest EU Research and Innovation programme ever. Funding opportunities under Horizon 2020 are set out in multi-annual work programmes – and the IMPC is currently looking for partners with which to submit funding applications under Societal Challenge 1 – Health, demographic change and wellbeing.

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Large-Scale Study Uncovers 198 Genes Associated With Brain Morphogenesis in Mice

With a contribution from the IMPC, recent research, published in Nature Communications, has identified 198 genes associated with brain morphogenesis in mice – 83% of these constitute genes newly implicated in brain architecture.

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Our Collaborations

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Maintaining and expanding a world-wide consortium of institutions

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