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Genes Phenotypes

Study Uncovers 198 Genes Associated With Brain Morphogenesis in Mice

With a contribution from the IMPC, recent research, published in Nature Communications, has identified 198 genes associated with brain morphogenesis…

Published: 4 Oct 2019

Knockout Mouse Model Reveals Insight into Traits Associated With PCD

Researchers have used embryonic stem (ES) cells produced as part of the IMPC project, to engineer a Ccdc151 'knockout' mouse…

Published: 16 Aug 2019

MRC: Rodent little brother project poster. Visit bit.ly/secretlivesofmice for more information

Can the Public Revolutionise How Mouse Models Are Studied?

In collaboration with NC3Rs, IMPC member institution MRC Harwell has launched a new citizen science project that aims to advance…

Published: 24 Jul 2019

PIK3CA inhibition with BYL719 - a novel treatment for CLOVES syndrome

CLOVES syndrome is a rare condition that is characterised by tissue overgrowth and vascular abnormalities, caused by mosaic gain-of-function mutations…

Published: 3 Jul 2019

SETD3 – An Actin Methyltransferase That Prevents Primary Dystocia

Research published in Nature identifies SET domain protein 3 (SETD3) as a physiological actin methyltransferase, and uncovers SETD3’s crucial role…

Published: 20 May 2019

Research Reveals Novel Genetic Influences On Osteoporosis

Recent research, published in nature genetics, identifies novel genetic influences on osteoporosis, with the potential to empower future research on…

Published: 19 Mar 2019

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Blog

Study Uncovers 198 Genes Associated With Brain Morphogenesis in Mice

Knockout Mouse Model Reveals Insight into Traits Associated With PCD

Can the Public Revolutionise How Mouse Models Are Studied?

PIK3CA inhibition with BYL719 - a novel treatment for CLOVES syndrome

SETD3 – An Actin Methyltransferase That Prevents Primary Dystocia

Research Reveals Novel Genetic Influences On Osteoporosis

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